{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:53:33Z","timestamp":1791194013233,"version":"4.1.0"},"reference-count":46,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100012519","name":"EHESP","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012519","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020992","name":"French national health insurance fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020992","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"French national research agency","doi-asserted-by":"publisher","award":["ANR-11-INBS-0002"],"award-info":[{"award-number":["ANR-11-INBS-0002"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Severe forms of musculoskeletal pain (MSP) with functional and occupational consequences are of growing concern in the context of an aging workforce and longer working lives. This study aimed to define a classification of MSP severity in the French population and to examine associations between MSP severity and sociodemographic characteristics and lifetime occupational biomechanical exposures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted cross-sectional analyses in the Constances cohort, among participants aged 45 years and older. Symptom duration of MSP in 6 body regions, functional limitations and job loss\/early retirement due to MSP were self-reported. Latent class analysis was performed separately for men and women. The resulting classification was described according to sociodemographic characteristics and 3 lifetime occupational biomechanical exposures, and its association with these variables was estimated using multinomial logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 74,581 participants (35,919 men and 38,662 women) were included. Four classes were identified for men and women: \u201cAbsence of MSP\u201d (men = 51.4%; women = 41.3%), \u201cSubacute MSP without functional limitations\u201d (24.4%; 27.7%), \u201cChronic MSP with moderate functional limitations\u201d (14.2%; 16.8%), and \u201cPermanent MSP with severe functional limitations and occupational consequences\u201d (10.0%; 14.2%). Compared with the \u201cAbsence of MSP\u201d class, the \u201cPermanent MSP with severe functional limitations and occupational consequences\u201d class was associated with lifetime occupational biomechanical exposures: forceful work\/manual handling of loads (men: OR 1.63, 95% CI 1.48 to 1.79; women: 1.31, 95% CI 1.17 to 1.45), strenuous postures (1.67, 1.51 to 1.85; 1.67, 1.56 to 1.79), and mechanical vibrations (1.59, 1.44 to 1.75; 1.61, 1.44 to 1.81). Similar associations were observed for the other MSP severity classes, except for mechanical vibrations, which were not associated with the \u201cChronic MSP with moderate functional limitations\u201d class among women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study defined a classification of MSP severity based on symptom duration, functional limitations, and occupational consequences. Four classes were identified in both men and women, describing a progressive gradient of severity. The most severe class, comprising 10% of men and 14% of women, was associated with each of the 3 lifetime occupational biomechanical exposures. These findings provide quantitative data on the different forms of MSP and on the populations most affected by the severe forms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/annweh\/wxag084","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:20:45Z","timestamp":1789672845000},"source":"Crossref","is-referenced-by-count":0,"title":["Classification of musculoskeletal pain severity in the Constances cohort: a latent class analysis"],"prefix":"10.1093","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7531-5781","authenticated-orcid":false,"given":"Gwladys","family":"Morvan","sequence":"first","affiliation":[{"name":"Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Sant\u00e9, Environnement et Travail)-UMR_S 1085 , Ester Team, SFR ICAT, Angers F-49000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Bodin","sequence":"additional","affiliation":[{"name":"Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Sant\u00e9, Environnement et Travail)-UMR_S 1085 , Ester Team, SFR ICAT, Angers F-49000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0263-8978","authenticated-orcid":false,"given":"Natacha","family":"Fouquet","sequence":"additional","affiliation":[{"name":"Sant\u00e9 publique France, French national public health agency , F-94410 Saint-Maurice ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanifa","family":"Bouziri","sequence":"additional","affiliation":[{"name":"Inserm, Universit\u00e9 Paris Cit\u00e9, Universit\u00e9 Paris Saclay, Universit\u00e9 de Versailles-Saint-Quentin-en-Yvelines (UVSQ) , UMS 11 \u201cPopulation-based Epidemiological Cohorts Unit\u201d, UMS 011, Villejuif 94800 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Gilbert","sequence":"additional","affiliation":[{"name":"Inserm, Universit\u00e9 Paris Cit\u00e9, Universit\u00e9 Paris Saclay, Universit\u00e9 de Versailles-Saint-Quentin-en-Yvelines (UVSQ) , UMS 11 \u201cPopulation-based Epidemiological Cohorts Unit\u201d, UMS 011, Villejuif 94800 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1554-0021","authenticated-orcid":false,"given":"Marc","family":"Fadel","sequence":"additional","affiliation":[{"name":"Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Sant\u00e9, Environnement et Travail)-UMR_S 1085 , Ester Team, SFR ICAT, Angers F-49000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Eve","family":"Major","sequence":"additional","affiliation":[{"name":"Department of Industrial Relations, University of Laval , Quebec City, QC G1V 0A6 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Roquelaure","sequence":"additional","affiliation":[{"name":"Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Sant\u00e9, Environnement et Travail)-UMR_S 1085 , Ester Team, SFR ICAT, Angers F-49000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"2026100505120125500_wxag084-B1","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1093\/workar\/waab014","article-title":"Physical work exposures of older workers: does measurement make a difference?","volume":"9","author":"Andrasfay","year":"2023","journal-title":"Work Aging Retire"},{"key":"2026100505120125500_wxag084-B2","doi-asserted-by":"publisher","first-page":"100990","DOI":"10.1016\/j.ssmph.2021.100990","article-title":"Physical work conditions and disparities in later life functioning: potential pathways","volume":"16","author":"Andrasfay","year":"2021","journal-title":"SSM\u2014Popul Health"},{"key":"2026100505120125500_wxag084-B3","volume-title":"M\u00e9thode d'analyse de la charge physique de travail. 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