{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:28:03Z","timestamp":1790674083392,"version":"4.1.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2018,6,26]],"date-time":"2018-06-26T00:00:00Z","timestamp":1529971200000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Lyme Disease Research Foundation"},{"name":"Steven and Alexandra Cohen Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6,1]]},"DOI":"10.1093\/arclin\/acy051","type":"journal-article","created":{"date-parts":[[2018,5,24]],"date-time":"2018-05-24T19:10:32Z","timestamp":1527189032000},"page":"455-465","source":"Crossref","is-referenced-by-count":38,"title":["Cognitive Decline in Post-treatment Lyme Disease Syndrome"],"prefix":"10.1093","volume":"34","author":[{"given":"Pegah","family":"Touradji","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John N","family":"Aucott","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison W","family":"Rebman","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen T","family":"Bechtold","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,6,26]]},"reference":[{"key":"2019051003594404800_acy051C1","doi-asserted-by":"crossref","first-page":"e0116767","DOI":"10.1371\/journal.pone.0116767","article-title":"Health care costs, utilization and patterns of care following Lyme disease","volume":"10","author":"Adrion","year":"2015","journal-title":"PLoS One"},{"key":"2019051003594404800_acy051C2","volume-title":"Manual of directions and scoring","author":"Army Individual Test Battery","year":"1944"},{"key":"2019051003594404800_acy051C3","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.ijid.2013.01.008","article-title":"Development of a foundation for a case definition of post-treatment Lyme disease syndrome","volume":"17","author":"Aucott","year":"2013","journal-title":"International Journal of Infectious Diseases"},{"key":"2019051003594404800_acy051C4","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s11136-012-0126-6","article-title":"Post-treatment Lyme disease syndrome symptomatology and the impact on life functioning: Is there something here?","volume":"22","author":"Aucott","year":"2013","journal-title":"Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation"},{"key":"2019051003594404800_acy051C5","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/arclin\/acw098","article-title":"Standardized symptom measurement of individuals with early Lyme disease over time","volume":"32","author":"Bechtold","year":"2017","journal-title":"Archives of Clinical Neuropsychology"},{"key":"2019051003594404800_acy051C6","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1076\/clin.12.1.43.1726","article-title":"Hopkins Verbal Learning Test\u2014Revised: Normative data and analysis of inter-form and test\u2013retest reliability","volume":"12","author":"Benedict","year":"1998","journal-title":"Clinical Neuropsychologist"},{"key":"2019051003594404800_acy051C7","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1214\/aos\/1013699998","article-title":"The control of the false discovery rate in multiple testing under dependency","volume":"29","author":"Benjamini","year":"2001","journal-title":"Annals of Statistics"},{"key":"2019051003594404800_acy051C8","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1600-0404.1995.tb07020.x","article-title":"Lyme encephalopathy: Long-term neuropsychological deficits years after acute neuroborreliosis","volume":"91","author":"Benke","year":"1995","journal-title":"Acta Neurologica Scandinavica"},{"key":"2019051003594404800_acy051C9","first-page":"590","article-title":"Recommendations for test performance and interpretation from the second national conference on serologic diagnosis of Lyme disease","volume":"44","author":"CDC","year":"1995","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"2019051003594404800_acy051C10","author":"CDC","year":"2011"},{"key":"2019051003594404800_acy051C11","author":"CDC","year":"2011"},{"key":"2019051003594404800_acy051C12","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.psym.2013.04.003","article-title":"Correlates of perceived health-related quality of life in post-treatment Lyme encephalopathy","volume":"54","author":"Chandra","year":"2013","journal-title":"Psychosomatics: Journal of Consultation and Liaison Psychiatry"},{"key":"2019051003594404800_acy051C13","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1017\/S0033291709992054","article-title":"Cognitive functioning in chronic fatigue syndrome: A meta-analysis","volume":"40","author":"Cockshell","year":"2010","journal-title":"Psychological Medicine"},{"key":"2019051003594404800_acy051C14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s11926-016-0577-9","article-title":"Cognitive dysfunction in chronic fatigue syndrome: A review of recent evidence","volume":"18","author":"Cvejic","year":"2016","journal-title":"Current Rheumatology Reports"},{"key":"2019051003594404800_acy051C15","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1176\/jnp.15.3.326","article-title":"Regional cerebral blood flow and cognitive deficits in chronic Lyme disease","volume":"15","author":"Fallon","year":"2003","journal-title":"The Journal of Neuropsychiatry and Clinical Neurosciences"},{"key":"2019051003594404800_acy051C16","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1001\/archgenpsychiatry.2009.29","article-title":"Regional cerebral blood flow and metabolic rate in persistent Lyme encephalopathy","volume":"66","author":"Fallon","year":"2009","journal-title":"Archives of General Psychiatry"},{"key":"2019051003594404800_acy051C17","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1056\/NEJMra072023","article-title":"A critical appraisal of \u201cchronic Lyme disease\u201d","volume":"357","author":"Feder","year":"2007","journal-title":"The New England Journal of Medicine"},{"key":"2019051003594404800_acy051C18","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1001\/archneur.1997.00550230045015","article-title":"Post-Lyme syndrome and chronic fatigue syndrome. Neuropsychiatric similarities and differences","volume":"54","author":"Gaudino","year":"1997","journal-title":"Archives of Neurology"},{"key":"2019051003594404800_acy051C19","volume-title":"The Word Memory Test: A user\u2019s guide to the oral and computer-administered forms, U.S. version 1.1","author":"Green","year":"1996"},{"key":"2019051003594404800_acy051C20","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/cid\/ciu397","article-title":"Lyme disease testing by large commercial laboratories in the United States","volume":"59","author":"Hinckley","year":"2014","journal-title":"Clinical Infectious Diseases"},{"key":"2019051003594404800_acy051C21","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1080\/13854046.2012.733732","article-title":"Relationship between performance validity testing, disability status, and somatic complaints in patients with fibromyalgia","volume":"27","author":"Johnson-Greene","year":"2013","journal-title":"The Clinical Neuropsychologist"},{"key":"2019051003594404800_acy051C22","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1207\/s15324826an0601_1","article-title":"Neuropsychological deficits in Lyme disease patients with and without other evidence of central nervous system pathology","volume":"6","author":"Kaplan","year":"1999","journal-title":"Applied Neuropsychology"},{"key":"2019051003594404800_acy051C23","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1212\/WNL.42.7.1263","article-title":"Memory impairment and depression in patients with Lyme encephalopathy: Comparison with fibromyalgia and nonpsychotically depressed patients","volume":"42","author":"Kaplan","year":"1992","journal-title":"Neurology"},{"key":"2019051003594404800_acy051C24","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1212\/01.WNL.0000068030.26992.25","article-title":"Cognitive function in post-treatment Lyme disease: Do additional antibiotics help?","volume":"60","author":"Kaplan","year":"2003","journal-title":"Neurology"},{"key":"2019051003594404800_acy051C25","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1017\/S1355617706060231","article-title":"WAIS-III and WMS-III performance in chronic Lyme disease","volume":"12","author":"Keilp","year":"2006","journal-title":"Journal of the International Neuropsychological Society"},{"key":"2019051003594404800_acy051C26","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1056\/NEJM200107123450202","article-title":"Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease","volume":"345","author":"Klempner","year":"2001","journal-title":"The New England Journal of Medicine"},{"key":"2019051003594404800_acy051C27","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1001\/archneur.1991.00530230033017","article-title":"Cognitive functioning in late Lyme borreliosis","volume":"48","author":"Krupp","year":"1991","journal-title":"Archives of Neurology"},{"key":"2019051003594404800_acy051C28","article-title":"CDC estimates 300,000 US cases of Lyme disease annually","volume":"310","author":"Kuehn","year":"2013","journal-title":"The Journal of the American Medical Association"},{"key":"2019051003594404800_acy051C29","volume-title":"Neuropsychological Assessment","author":"Lezak","year":"2004","edition":"4th ed."},{"key":"2019051003594404800_acy051C30","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0002-9343(03)00308-5","article-title":"Long-term follow-up of patients with culture-confirmed Lyme disease","volume":"115","author":"Nowakowski","year":"2003","journal-title":"The American Journal of Medicine"},{"key":"2019051003594404800_acy051C31","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1207\/s15324826an0601_4","article-title":"Does process-specific slowing account for cognitive deficits in Lyme disease?","volume":"6","author":"Pollina","year":"1999","journal-title":"Applied Neuropsychology"},{"key":"2019051003594404800_acy051C32","first-page":"72","article-title":"Cognitive processing speed in Lyme disease","volume":"12","author":"Pollina","year":"1999","journal-title":"Neuropsychiatry, Neuropsychology, and Behavioral Neurology"},{"key":"2019051003594404800_acy051C33","first-page":"282","article-title":"Memory functioning in Lyme borreliosis","volume":"57","author":"Ravdin","year":"1996","journal-title":"The Journal of Clinical Psychiatry"},{"key":"2019051003594404800_acy051C34","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1177\/1049732315619380","article-title":"Living in limbo: Contested narratives of patients with chronic symptoms following Lyme disease","volume":"27","author":"Rebman","year":"2015","journal-title":"Qualitative Health Research"},{"key":"2019051003594404800_acy051C35","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1017\/S1355617708080387","article-title":"Frequency and bases of abnormal performance by healthy adults on neuropsychological testing","volume":"14","author":"Schretlen","year":"2008","journal-title":"Journal of the International Neuropsychological Society"},{"key":"2019051003594404800_acy051C36","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1177\/1073191111428764","article-title":"Reliable Digit Span: A systematic review and cross-validation study","volume":"19","author":"Schroeder","year":"2012","journal-title":"Assessment"},{"key":"2019051003594404800_acy051C37","doi-asserted-by":"crossref","first-page":"919","DOI":"10.7326\/0003-4819-131-12-199912210-00003","article-title":"Musculoskeletal and neurologic outcomes in patients with previously treated Lyme disease","volume":"131","author":"Shadick","year":"1999","journal-title":"Annals of Internal Medicine"},{"key":"2019051003594404800_acy051C38","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM200107123450207","article-title":"Lyme disease","volume":"345","author":"Steere","year":"2001","journal-title":"The New England Journal of Medicine"},{"key":"2019051003594404800_acy051C39","doi-asserted-by":"crossref","first-page":"16090","DOI":"10.1038\/nrdp.2016.90","article-title":"Lyme borreliosis","volume":"2","author":"Steere","year":"2016","journal-title":"Nature Reviews Disease Primers"},{"key":"2019051003594404800_acy051C40","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/13854048708520046","article-title":"Comparison of three tests of attention and rapid information processing across six age groups","volume":"1","author":"Stuss","year":"1987","journal-title":"The Clinical Neuropsychologist"},{"key":"2019051003594404800_acy051C41","first-page":"199","article-title":"Abnormal neuropsychological findings are not necessarily a sign of cerebral impairment: A matched comparison between chronic fatigue syndrome and multiple sclerosis","volume":"13","author":"van der Werf","year":"2000","journal-title":"Neuropsychiatry, Neuropsychology, & Behavioral Neurology"},{"key":"2019051003594404800_acy051C42","volume-title":"Wechsler Adult Intelligence Scale","author":"Wechsler","year":"2008","edition":"4th edn"},{"key":"2019051003594404800_acy051C43","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1023\/A:1020381913563","article-title":"Neuropsychological functioning in chronic Lyme disease","volume":"12","author":"Westervelt","year":"2002","journal-title":"Neuropsychology Review"},{"key":"2019051003594404800_acy051C44","volume-title":"Wide Range Achievement Test","author":"Wilkinson","year":"2006","edition":"4th ed."},{"key":"2019051003594404800_acy051C45","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1086\/508667","article-title":"The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: Clinical practice guidelines by the infectious diseases society of America","volume":"43","author":"Wormser","year":"2006","journal-title":"Clinical Infectious Diseases"}],"container-title":["Archives of Clinical Neuropsychology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/acn\/article-pdf\/34\/4\/455\/28576268\/acy051.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T04:02:35Z","timestamp":1661313755000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/acn\/article\/34\/4\/455\/5045218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":45,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,6,26]]},"published-print":{"date-parts":[[2019,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/arclin\/acy051","relation":{},"ISSN":["1873-5843"],"issn-type":[{"value":"1873-5843","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,6]]},"published":{"date-parts":[[2018,6]]}}}