{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T03:32:01Z","timestamp":1783567921636,"version":"3.55.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T00:00:00Z","timestamp":1655337600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The recall of Allergan Biocell (Irvine, CA) devices due to the association between anaplastic large cell lymphoma (ALCL) and macrotextured breast implants means that plastic surgeons are faced with the challenge of caring for patients with these implants in situ. Cosmetic and reconstructive surgeons have been contacting affected patients to encourage them to follow up and discuss the most appropriate risk-reduction strategies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The aim of this study was to evaluate patient concerns about the risk of breast implant\u2013associated ALCL (BIA-ALCL) and to compare management differences between cosmetic and reconstructive patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective review was performed of 432 patients with macrotextured implants who presented to clinic after being contacted (121 reconstructive and 311 cosmetic). These records were analyzed for their presenting concerns, surgery wait times, and management plans. Statistical analysis was performed to compare the cohorts, and odds ratios (ORs) were computed to determine the association between patient concerns and their choice of management.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>After consultation, 59.5% of the reconstructive cohort and 49.5% of the cosmetic cohort scheduled implant removal or exchange. The reconstructive population had a higher rate of ALCL concern (62.7%); however, both cohorts had a significant OR, demonstrating an expressed fear of ALCL likely contributed to their subsequent clinical management (OR cosmetic, 1.66; OR reconstructive, 2.17).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Although the risk of ALCL appears to be more concerning to the reconstructive population, both cohorts were equally motivated to have their implants removed. Informing patients about their ALCL risk is crucial to ensure a patient-supported risk reduction plan.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Level of Evidence: 2<\/jats:title>\n                  <jats:p\/>\n               <\/jats:sec>","DOI":"10.1093\/asj\/sjac158","type":"journal-article","created":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T19:18:56Z","timestamp":1655407136000},"page":"1408-1413","source":"Crossref","is-referenced-by-count":12,"title":["The Macrotextured Implant Recall: Breast Implant\u2013Associated-Anaplastic Large Cell Lymphoma Risk Aversion in Cosmetic and Reconstructive Plastic Surgery Practices"],"prefix":"10.1093","volume":"42","author":[{"given":"Peter","family":"Mankowski","sequence":"first","affiliation":[{"name":"University of British Columbia Department of Surgery, Division of Plastic Surgery, Vancouver General Hospital , Vancouver, BC , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Carr","sequence":"additional","affiliation":[{"name":"University of British Columbia Department of Surgery, Division of Plastic Surgery, Vancouver General Hospital , Vancouver, BC , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhiram","family":"Cherukupalli","sequence":"additional","affiliation":[{"name":"University of British Columbia Department of Surgery, Division of Plastic Surgery, Vancouver General Hospital , Vancouver, BC , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esta","family":"Bovill","sequence":"additional","affiliation":[{"name":"University of British Columbia Department of Surgery, Division of Plastic Surgery, Vancouver General Hospital , Vancouver, BC , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Lennox","sequence":"additional","affiliation":[{"name":"University of British Columbia Department of Surgery, Division of Plastic Surgery, Vancouver General Hospital , Vancouver, BC , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7556-5423","authenticated-orcid":false,"given":"Mitchell H","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Toronto , Toronto, Ontario , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Carr","sequence":"additional","affiliation":[{"name":"University of British Columbia Department of Surgery, Division of Plastic Surgery, Vancouver General Hospital , Vancouver, BC , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,6,16]]},"reference":[{"key":"2023012005131268700_CIT0001","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1038\/modpathol.3801024","article-title":"Seroma-associated primary anaplastic large-cell lymphoma adjacent to breast implants: an indolent T-cell lymphoproliferative disorder","volume":"21","author":"Roden","year":"2008","journal-title":"Mod Pathol."},{"key":"2023012005131268700_CIT0002","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.3109\/10428194.2011.574755","article-title":"Primary anaplastic large-cell lymphoma associated with breast implants","volume":"52","author":"Popplewell","year":"2011","journal-title":"Leuk Lymphoma."},{"key":"2023012005131268700_CIT0003","author":"American Society of Plastic Surgeons.","year":"2019"},{"key":"2023012005131268700_CIT0004","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.1097\/PRS.0b013e3182172418","article-title":"Anaplastic large cell lymphoma and breast implants: a systematic review","volume":"127","author":"Kim","year":"2011","journal-title":"Plast Reconstr Surg."},{"key":"2023012005131268700_CIT0005","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1093\/asj\/sjz343","article-title":"Is banning texturized implants to prevent breast implant-associated anaplastic large cell lymphoma a rational decision? A meta-analysis and cost-effectiveness study","volume":"40","author":"Danilla","year":"2020","journal-title":"Aesthet Surg J."},{"key":"2023012005131268700_CIT0006","doi-asserted-by":"publisher","first-page":"NP474","DOI":"10.1093\/asj\/sjaa053","article-title":"Banning textured implants is a rational decision to eliminate the risk of breast implant\u2013associated anaplastic large-cell lymphoma (BIA-ALCL)","volume":"40","author":"Swanson","year":"2020","journal-title":"Aesthet Surg J."},{"key":"2023012005131268700_CIT0007","author":"Harrop","year":"2019"},{"key":"2023012005131268700_CIT0008","doi-asserted-by":"publisher","DOI":"10.1093\/asjof\/ojz025","article-title":"Management of asymptomatic patients with textured surface breast implants","volume":"1ojz025","author":"McGuire","year":"2019","journal-title":"Aesthet Surg J Open Forum"},{"key":"2023012005131268700_CIT0009","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1016\/j.ejso.2017.05.004","article-title":"Breast implant associated anaplastic large cell lymphoma: the UK experience. Recommendations on its management and implications for informed consent","volume":"43","author":"Johnson","year":"2017","journal-title":"Eur J Surg Oncol."},{"key":"2023012005131268700_CIT0010","doi-asserted-by":"publisher","first-page":"144e","DOI":"10.1097\/PRS.0000000000001416","article-title":"Breast implant\u2013associated anaplastic large cell lymphoma: proposal for a monitoring protocol","volume":"136","author":"di Pompeo","year":"2015","journal-title":"Plast Reconstr Surg."},{"key":"2023012005131268700_CIT0011","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1097\/PRS.0000000000005703","article-title":"A prospective approach to inform and treat 1340 patients at risk for BIA-ALCL","volume":"144","author":"Roberts","year":"2019","journal-title":"Plast Reconstr Surg."},{"key":"2023012005131268700_CIT0012","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1097\/01.prs.0000481103.45976.b1","article-title":"Breast implant informed consent should include the risk of anaplastic large cell lymphoma","volume":"137","author":"Clemens","year":"2016","journal-title":"Plast Reconstr Surg."},{"key":"2023012005131268700_CIT0013","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1097\/SAP.0b013e31804d442e","article-title":"Anaplastic large cell lymphoma arising in a saline breast implant capsule after tissue expander breast reconstruction","volume":"59","author":"Olack","year":"2007","journal-title":"Ann Plast Surg."}],"container-title":["Aesthetic Surgery Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/asj\/advance-article-pdf\/doi\/10.1093\/asj\/sjac158\/45050406\/sjac158.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/asj\/article-pdf\/42\/12\/1408\/48791294\/sjac158.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/asj\/article-pdf\/42\/12\/1408\/48791294\/sjac158.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T05:15:29Z","timestamp":1674191729000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/asj\/article\/42\/12\/1408\/6609452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,16]]},"references-count":13,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,6,16]]},"published-print":{"date-parts":[[2022,12,14]]}},"URL":"https:\/\/doi.org\/10.1093\/asj\/sjac158","relation":{},"ISSN":["1090-820X","1527-330X"],"issn-type":[{"value":"1090-820X","type":"print"},{"value":"1527-330X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,12,1]]},"published":{"date-parts":[[2022,6,16]]}}}