{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T06:10:52Z","timestamp":1783491052963,"version":"3.55.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T00:00:00Z","timestamp":1739145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Patients with gynecomastia may experience hormonal imbalances and sexual dysfunctions, such as erectile and ejaculatory disorders.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study evaluates the changes in hormonal parameters and sexual function following gynecomastia surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Thirty-two male patients (aged 15-65) without systemic or genetic comorbidities underwent gynecomastia surgery. Preoperative and postoperative hormonal parameters free and total testosterone, estrogen (EST), prolactin (PRL), follicle-stimulating hormone, luteinizing hormone, sex hormone\u2013binding globulin, and sexual function scores (International Index of Erectile Function [IIEF], Premature Ejaculation Diagnostic Tool [PEDT]) were assessed. A urologist blinded to the study evaluated patients andrologically.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The mean age of the patients was 25.69 \u00b1 10.37 years. Postoperative PRL and EST levels significantly decreased (P = .03 and P &amp;lt; .001, respectively). All IIEF subscale scores showed significant postoperative improvements (P-values ranging from &amp;lt;.001 to .006). PEDT scores significantly decreased postoperatively (P &amp;lt; .001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Surgical treatment of gynecomastia leads to significant improvements in hormonal parameters and sexual function. These benefits should be considered in surgical planning.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Level of Evidence: 4<\/jats:title>\n                  <jats:p\/>\n               <\/jats:sec>","DOI":"10.1093\/asj\/sjaf026","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T05:56:49Z","timestamp":1739167009000},"page":"584-588","source":"Crossref","is-referenced-by-count":2,"title":["Evaluating the Role of Gynecomastia Surgery in Improving Sexual Function and Hormonal Profiles"],"prefix":"10.1093","volume":"45","author":[{"given":"Tansu","family":"Akda\u011f","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Akda\u011f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"\u00d6zkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman Enver","family":"Ayd\u0131n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,2,10]]},"reference":[{"key":"2025052712253195800_sjaf026-B1","first-page":"1119","volume-title":"Plastic Surgery: Principles and Practice","author":"McGrath","year":"1990"},{"key":"2025052712253195800_sjaf026-B2","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1111\/andr.12636","article-title":"EAA clinical practice guidelines-gynecomastia evaluation and management","volume":"7","author":"Kanakis","year":"2019","journal-title":"Andrology"},{"key":"2025052712253195800_sjaf026-B3","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1056\/NEJMcp070677","article-title":"Clinical practice. 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