{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T13:02:13Z","timestamp":1792069333163,"version":"4.4.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100016211","name":"Zonguldak B\u00fclent Ecevit University","doi-asserted-by":"publisher","award":["2019-98417285-01"],"award-info":[{"award-number":["2019-98417285-01"]}],"id":[{"id":"10.13039\/501100016211","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Capsular contracture leads to undesirable outcomes when using breast prostheses. Although implant characteristics and surgical techniques have been studied extensively, the impact of suture materials on capsule formation remains unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The aim of the authors of this study is to evaluate the effects of different suture materials on capsular contracture development in a rat model with silicone implants.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The rats were divided into 5 groups. Silicone measuring 1.0 \u00d7 1.0 \u00d7 0.5\u2005cm was implanted in the thoracodorsal region. The incisions were closed using poly(glycolide-co-lactide), polypropylene, polydioxanone, Glycomer 631, and polyglycolide-co-caprolactone in Groups 1 to 5, respectively. The capsule surrounding the implant was examined in histopathological specimens collected during the 12th week after implantation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Capsule thickness varied significantly among groups, with Group 1 exhibiting the highest mean thickness and Group 4 the lowest. Inflammation levels also differed, with Group 3 showing the highest proportion of moderate to severe inflammation, whereas Group 4 primarily exhibited mild inflammation. The type of inflammation varied, with Groups 3, 4, and 5 predominantly showing mixed-type inflammation. The presence of foreign body giant cells was highest in Groups 1 and 2, whereas Group 4 had the lowest. No significant differences were observed in hemosiderin presence, collagen organization, or myofibroblast density.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>In terms of the type and degree of inflammation, presence of foreign body giant cells, and average capsule thickness, Group 4 (Glycomer 631) suture had the best overall performance, and Group 1 (poly(glycolide-co-lactide)) performed the worst. Glycomer 631 sutures may reduce capsular contracture in silicone implant surgeries compared with other suture materials.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/asj\/sjaf140","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T18:08:49Z","timestamp":1752775729000},"page":"1198-1205","source":"Crossref","is-referenced-by-count":2,"title":["The Effect of Suture Materials on the Development of Capsular Contracture in Silicone Implants"],"prefix":"10.1093","volume":"45","author":[{"given":"Emrah","family":"I\u015f\u0131ktekin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8728-279X","authenticated-orcid":false,"given":"Bur\u00e7in","family":"Acuner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merve","family":"Torun 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