{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T02:48:37Z","timestamp":1781664517147,"version":"3.54.5"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Research Fund of Rigshospitalet"},{"DOI":"10.13039\/501100003554","name":"Lundbeck Foundation","doi-asserted-by":"publisher","award":["R413-2022-621"],"award-info":[{"award-number":["R413-2022-621"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Capital Region of Denmark Research Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Baker classification is used to grade capsular contracture after breast-implant surgery; yet, its correlation with patient-reported outcomes is poor.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine whether histopathological verification of capsular contracture status strengthens the association between Baker grade and BREAST-Q scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Women scheduled for implant exchange or removal completed the BREAST-Q \u201cPhysical Well-Being-Chest\u201d module. Raw BREAST-Q sum scores were transformed to a 0-100 scale, where higher scores indicate increased comfort. The attending surgeon classified breasts using the Baker scale (I-IV). Capsule biopsies were scored with a validated histopathological scoring system. Baker grades were deemed \u201cconfirmed\u201d when histology and Baker grade were aligned and otherwise deemed \u201cmisclassified\u201d. Linear regressions compared the relationship between BREAST-Q scores and Baker grade in confirmed vs misclassified cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 103 patients (58 augmentation, 45 reconstruction) were included. The Baker classification was confirmed histologically in 53\/58 augmentation patients (91%), and 36\/45 reconstruction patients (80%). In confirmed augmentation cases, each one-grade increase in Baker significantly worsened chest well-being by \u22128.80 BREAST-Q points (95% CI [\u221214.42, \u22123.18]; P = .003). No correlation was found in the misclassified augmentation cases (\u22123.21 points; P = .57), confirmed reconstruction cases (\u22125.00 points; P = .19), or in the misclassified reconstruction cases (\u22125.72 points; P = .54).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Histologically confirmed Baker classification correlates significantly with chest well-being assessed with BREAST-Q for the patients with breast augmentation, whereas no such correlation was observed in cases where the histology and Baker classification showed a mismatch. This suggests that histopathological scoring can increase diagnostic accuracy when assessing capsular contracture status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence: 3 (Therapeutic)<\/jats:title>\n                    <jats:p\/>\n                  <\/jats:sec>","DOI":"10.1093\/asj\/sjaf241","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T12:55:42Z","timestamp":1763211342000},"page":"302-309","source":"Crossref","is-referenced-by-count":1,"title":["Histopathological Scoring Improves the Correlation Between Capsular Contracture Diagnosis and Patient-Reported Outcomes"],"prefix":"10.1093","volume":"46","author":[{"given":"Maria O","family":"Snog","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim K","family":"Weltz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mads 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