{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:05:08Z","timestamp":1789517108185,"version":"build-2803163510"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Reduction mammoplasty is an established treatment for symptomatic macromastia. Understanding risk factors associated with complications is essential for counseling and patient selection. The modified frailty index (mFI-5) has been proposed as a simple tool to assess risk in surgical candidates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The authors sought to determine whether the mFI-5 can accurately predict wound-healing complications following reduction mammoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review was performed of primary bilateral reduction mammoplasty cases between 2017 and 2019 at 1 institution. mFI-5 scores were calculated for each patient. Thirty-day wound-healing complications were defined as incisional dehiscence, T-point breakdown, nipple\u2013areolar complex necrosis, and fat necrosis. Univariate and multivariate logistic regression were used to evaluate predictive value.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Four hundred and seventy-four patients were stratified into 3 age groups: 15 to 30, 31 to 50, and &amp;gt;51. Twenty-six percent of patients developed 1 wound-healing problem. On univariate analysis, ages 31 to 50 and 51+ (odds ratio [OR] = 2.75 and 3.16) and mFI score of 1 (OR = 2.07) were associated with an increased risk of wound-healing complications. Adjusted multivariate analysis indicated that age &amp;gt;51 years significantly predicted wound-healing issues (OR = 2.89; P = .001) when controlled for the American Society of Anesthesiologists (ASA) score, smoking, and BMI. The mFI-5 did not significantly predict wound-healing issues when controlled for age, ASA, BMI, or smoking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In the study population, the mFI-5 was not a statistically significant predictor of wound-healing complications following reduction mammoplasty. When controlling for confounders, advanced age alone seems to place patients at higher risk for wound-healing complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence: 3 (Therapeutic)<\/jats:title>\n                    <jats:p>For image description, please refer to the figure legend and surrounding text.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/asj\/sjag026","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T10:18:08Z","timestamp":1769422688000},"page":"NP127-NP132","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating the Use of 5-Factor Modified Frailty Index to Predict Wound-Healing Complications in Reduction 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