{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T11:58:11Z","timestamp":1771675091179,"version":"3.50.1"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2019,10,20]],"date-time":"2019-10-20T00:00:00Z","timestamp":1571529600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Conventional treatment options for periorbital syringomas are often unsatisfactory because of inevitable surface damage from the procedure and frequent recurrence rate of the tumors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The authors sought to ascertain the efficacy and safety of intralesional electrosurgery utilizing a monopolar radiofrequency device with a single insulated microneedle for the treatment of periorbital syringomas.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective analysis was performed employing data from medical records, routine questionnaires, and clinical photographs of 55 patients with periorbital syringoma who underwent intralesional electrosurgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Approximately one-half of the patients (50.9%) experienced marked resolution after 1 treatment. The lesion clearance rate increased and lesion severity decreased each time the treatment was repeated. No persistent therapy-related adverse event was found except transient erythema or crusting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Intralesional electrosurgery with insulated microneedle is an effective and safe treatment option for periorbital syringomas.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Level of Evidence: 4<\/jats:title>\n                  <jats:p\/>\n               <\/jats:sec>","DOI":"10.1093\/asj\/sjz288","type":"journal-article","created":{"date-parts":[[2019,10,20]],"date-time":"2019-10-20T22:19:05Z","timestamp":1571609945000},"page":"490-498","source":"Crossref","is-referenced-by-count":5,"title":["Intralesional Electrocoagulation With Insulated Microneedle for the Treatment of Periorbital Syringomas: A Retrospective Analysis"],"prefix":"10.1093","volume":"41","author":[{"given":"Ga Ram","family":"Ahn","sequence":"first","affiliation":[{"name":"Department of Dermatology, Chung-Ang University Hospital , Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guk Jin","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Chung-Ang University Hospital , Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Min","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Chung-Ang University Hospital , Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Yeon","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Chung-Ang University Hospital , Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kapsok","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Chung-Ang University Hospital , Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang Kyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Chung-Ang University Hospital , Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beom Joon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Chung-Ang University Hospital , Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,10,20]]},"reference":[{"issue":"3","key":"2022112516191066800_CIT0001","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.1365-2133.2008.08746.x","article-title":"New concepts on the histogenesis of eccrine neoplasia from keratin expression in the normal eccrine gland, syringoma and poroma","volume":"159","author":"Langbein","year":"2008","journal-title":"Br J 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