{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T15:24:30Z","timestamp":1781364270985,"version":"3.54.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T00:00:00Z","timestamp":1635120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017643","name":"Suneva Medical","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017643","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:label\/>\n                  <jats:p>Congenital hypoplasia of the masseter muscle is a rare condition most commonly associated with craniofacial or poly-malformation syndromes, with a small number of reported idiopathic cases. The condition is most commonly managed by orthodonture and later surgical intervention; however, surgery is not an option for all patients. Nonsurgical approaches to correcting asymmetry may be considered for patients for whom the functional impact of hypoplasia has been largely managed and the patient\u2019s concern is primarily aesthetic. In this case study, the patient presented for a consultation seeking a nonsurgical solution for marked facial asymmetry. The patient underwent physical examination and magnetic resonance imaging to confirm diagnosis of congenital masseter muscle hypoplasia. To treat the asymmetry, a total of 9.6 cc of polymethyl methacrylate (PMMA)-collagen gel (Bellafill; Suneva Medical, Inc., San Diego, CA) was injected along the border of the mandible from the gonial angle out to the area of the mental foramen and slightly above over the course of 6 months (2 visits spaced 3 months apart) to provide long-term, nonsurgical correction. The patient was very satisfied with the results, highlighting the potential for PMMA-collagen gel to be used in clinical situations in which durable, nonsurgical correction of lower-face asymmetry is needed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Level of Evidence: 5<\/jats:title>\n                  <jats:p\/>\n               <\/jats:sec>","DOI":"10.1093\/asjof\/ojab040","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T17:44:01Z","timestamp":1635183841000},"source":"Crossref","is-referenced-by-count":2,"title":["Case Report of Idiopathic Masseteric Hypoplasia Treated With Polymethyl Methacrylate-Collagen Gel"],"prefix":"10.1093","volume":"4","author":[{"given":"Brian","family":"Windle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,10,25]]},"reference":[{"issue":"1","key":"2023021306012941600_CIT0001","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1597\/1545-1569_2003_040_0006_vasomm_2.0.co_2","article-title":"Volume and shape of masticatory muscles in patients with hemifacial microsomia","volume":"40","author":"Takashima","year":"2003","journal-title":"Cleft Palate Craniofac J."},{"issue":"1","key":"2023021306012941600_CIT0002","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00001665-200101000-00006","article-title":"Relationship in hypoplasia between the masticatory muscles and the craniofacial skeleton in hemifacial microsomia, as determined by 3-D CT imaging","volume":"12","author":"Huisinga-Fischer","year":"2001","journal-title":"J Craniofac Surg."},{"issue":"2","key":"2023021306012941600_CIT0003","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.tripleo.2004.03.011","article-title":"Morphologic characteristics of masseter muscle in cleidocranial dysplasia: a report of 3 cases","volume":"99","author":"Furuuchi","year":"2005","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod."},{"issue":"6","key":"2023021306012941600_CIT0004","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.arcped.2011.03.020","article-title":"[Cleidocranial dysplasia: report of 2 cases and literature review]","volume":"18","author":"Trigui","year":"2011","journal-title":"Arch Pediatr."},{"issue":"1","key":"2023021306012941600_CIT0005","doi-asserted-by":"crossref","first-page":"121","DOI":"10.2334\/josnusd.53.121","article-title":"Craniofacial and dental characteristics of Goldenhar syndrome: a report of two cases","volume":"53","author":"Tuna","year":"2011","journal-title":"J Oral Sci."},{"issue":"1","key":"2023021306012941600_CIT0006","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bjps.2012.07.028","article-title":"A range of malar and masseteric hypoplasia exists in Treacher Collins syndrome","volume":"66","author":"Wong","year":"2013","journal-title":"J Plast Reconstr Aesthet Surg."},{"issue":"3","key":"2023021306012941600_CIT0007","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1080\/08869634.2016.1192834","article-title":"Idiopathic hypoplasia of the masseter muscle: a case report","volume":"35","author":"Cossellu","year":"2017","journal-title":"Cranio."},{"key":"2023021306012941600_CIT0008","doi-asserted-by":"crossref","first-page":"S302","DOI":"10.1097\/DSS.0000000000000542","article-title":"Five-year safety and satisfaction study of PMMA-collagen in the correction of nasolabial folds","volume":"41","author":"Cohen","year":"2015","journal-title":"Dermatol Surg."},{"key":"2023021306012941600_CIT0009","author":"US Food and Drug Administration"},{"issue":"3","key":"2023021306012941600_CIT0010","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s00266-009-9413-1","article-title":"ArteFill permanent injectable for soft tissue augmentation: I. Mechanism of action and injection techniques","volume":"34","author":"Lemperle","year":"2010","journal-title":"Aesthetic Plast Surg."},{"issue":"3","key":"2023021306012941600_CIT0011","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00266-009-9414-0","article-title":"ArteFill permanent injectable for soft tissue augmentation: II. Indications and applications","volume":"34","author":"Lemperle","year":"2010","journal-title":"Aesthetic Plast Surg."},{"issue":"12","key":"2023021306012941600_CIT0012","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1097\/DSS.0000000000001877","article-title":"Histologic characterization of polymethylmethacrylate dermal filler biostimulatory properties in human skin","volume":"45","author":"Ronan","year":"2019","journal-title":"Dermatol Surg."},{"key":"2023021306012941600_CIT0013","volume-title":"Bellafill [Instructions for Use]","year":"2020"},{"issue":"3","key":"2023021306012941600_CIT0014","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/jocd.12539","article-title":"Optimizing outcomes with polymethylmethacrylate fillers","volume":"17","author":"Gold","year":"2018","journal-title":"J Cosmet Dermatol."},{"issue":"8","key":"2023021306012941600_CIT0015","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1097\/DSS.0000000000002222","article-title":"Postmarket experience of polymethylmethacrylate-collagen gel dermal filler","volume":"46","author":"Lehman","year":"2020","journal-title":"Dermatol Surg."},{"issue":"5","key":"2023021306012941600_CIT0016","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s002669900217","article-title":"PMMA-microspheres (Artecoll) for long-lasting correction of wrinkles: refinements and statistical results","volume":"22","author":"Lemperle","year":"1998","journal-title":"Aesthetic Plast Surg."},{"issue":"11 Pt 2","key":"2023021306012941600_CIT0017","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.2310\/6350.2005.31243","article-title":"Artecoll: the Arizona experience and lessons learned","volume":"31","author":"Thaler","year":"2005","journal-title":"Dermatol Surg."},{"issue":"5","key":"2023021306012941600_CIT0018","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1097\/PRS.0b013e31816b1385","article-title":"Complications after polymethylmethacrylate injections: report of 32 cases","volume":"121","author":"Salles","year":"2008","journal-title":"Plast Reconstr Surg."},{"issue":"4","key":"2023021306012941600_CIT0019","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1007\/s00266-012-9871-8","article-title":"Adverse results with PMMA fillers","volume":"36","author":"de Melo Carpaneda","year":"2012","journal-title":"Aesthetic Plast Surg."},{"issue":"2","key":"2023021306012941600_CIT0020","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1093\/asj\/sjv195","article-title":"Complications and management of polymethylmethacrylate (PMMA) injections to the midface","volume":"36","author":"Limongi","year":"2016","journal-title":"Aesthet Surg J."},{"issue":"1","key":"2023021306012941600_CIT0021","doi-asserted-by":"crossref","first-page":"e12755","DOI":"10.1111\/dth.12755","article-title":"Polymethylmethacrylate-induced nodules of the lips: clinical presentation and management by intralesional neodymium: YAG laser therapy","volume":"32","author":"Goldman","year":"2019","journal-title":"Dermatol Ther."},{"issue":"1","key":"2023021306012941600_CIT0022","doi-asserted-by":"crossref","DOI":"10.1093\/asjof\/ojaa002","article-title":"Polymethyl methacrylate (PMMA) in the treatment of a case of hemifacial microsomia","volume":"2","author":"Milhomem","year":"2020","journal-title":"Aesthet Surg J Open Forum."}],"container-title":["Aesthetic Surgery Journal Open Forum"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/asjopenforum\/advance-article-pdf\/doi\/10.1093\/asjof\/ojab040\/40842978\/ojab040.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/asjopenforum\/article-pdf\/doi\/10.1093\/asjof\/ojab040\/49164183\/ojab040.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/asjopenforum\/article-pdf\/doi\/10.1093\/asjof\/ojab040\/49164183\/ojab040.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T06:01:54Z","timestamp":1676268114000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/asjopenforum\/article\/doi\/10.1093\/asjof\/ojab040\/6409996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,25]]},"references-count":22,"URL":"https:\/\/doi.org\/10.1093\/asjof\/ojab040","relation":{},"ISSN":["2631-4797"],"issn-type":[{"value":"2631-4797","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,1,1]]},"published":{"date-parts":[[2021,10,25]]},"article-number":"ojab040"}}