{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:42:41Z","timestamp":1793378561266,"version":"4.5.0"},"reference-count":47,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"vor","delay-in-days":58,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u00a0<\/jats:title>\n                  <jats:p>Lymphedema is a severe debilitating disease characterized by the accumulation of excessive protein-rich fluid in the interstitial space. Given the severe morbidity associated with this disease process, various surgical and nonsurgical treatment modalities have been developed to attempt to reduce the incidence and symptoms associated with lymphedema. Manual lymphatic drainage (MLD) is a component of complete decongestive therapy on-surgical treatment which has demonstrated benefit in reducing the development of lymphedema following surgery. Here we provide a review of literature on MLD and its potential mechanism of action. This paper aims to educate patients, physicians, and surgeons about MLD regarding its efficacy and utility in the treatment paradigm for lymphedema and to translate concepts from the treatment of lymphedema to cosmetic procedures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Level of Evidence: 5<\/jats:title>\n                  <jats:p\/>\n               <\/jats:sec>","DOI":"10.1093\/asjof\/ojad023","type":"journal-article","created":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T03:19:25Z","timestamp":1677554365000},"source":"Crossref","is-referenced-by-count":13,"title":["The Utility of Lymphatic Massage in Cosmetic Procedures"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8943-4929","authenticated-orcid":false,"given":"Troy","family":"Marxen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orr","family":"Shauly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedram","family":"Goel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Tsan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Faria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J","family":"Gould","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,2,28]]},"reference":[{"issue":"1","key":"2023070811172329300_ojad023-B1","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.soncn.2012.11.002","article-title":"Pathophysiology of lymphedema","volume":"29","author":"Ridner","year":"2013","journal-title":"Semin Oncol Nurs"},{"issue":"6","key":"2023070811172329300_ojad023-B2","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1136\/jmg.2008.064469","article-title":"Recessive primary congenital lymphoedema caused by a VEGFR3 mutation","volume":"46","author":"Ghalamkarpour","year":"2009","journal-title":"J Med Genet"},{"issue":"2","key":"2023070811172329300_ojad023-B3","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1089\/lrb.2007.1022","article-title":"Candidate gene analysis in primary lymphedema","volume":"6","author":"Ferrell","year":"2008","journal-title":"Lymphatic Res Biol"},{"issue":"2","key":"2023070811172329300_ojad023-B4","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s10549-008-9932-5","article-title":"Lymphatic venous anastomosis (LVA) for treatment of secondary arm lymphedema. A prospective study of 11 LVA procedures in 10 patients with breast cancer related lymphedema and a critical review of the literature","volume":"113","author":"Damstra","year":"2009","journal-title":"Breast Cancer Res Treat"},{"issue":"2","key":"2023070811172329300_ojad023-B5","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1007\/BF02032548","article-title":"The effect of a combined HeNe and i.r. laser treatment on the regeneration of the lymphatic system during the process of wound healing","volume":"6","author":"Lievens","year":"1991","journal-title":"Laser Med Sci"},{"issue":"10","key":"2023070811172329300_ojad023-B6","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.3109\/14653249.2011.594791","article-title":"Autologous stem cells for the treatment of post-mastectomy lymphedema: a pilot 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