{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:03:29Z","timestamp":1780344209454,"version":"3.54.1"},"reference-count":18,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T00:00:00Z","timestamp":1694822400000},"content-version":"vor","delay-in-days":258,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u00a0<\/jats:title>\n                  <jats:p>Pyoderma gangrenosum (PG) is a relatively uncommon inflammatory skin disorder that is characterized by rapid onset, ulcerative lesions, and often triggered by trauma or surgery. Although rare, PG of the breast has been well described in the plastic surgery literature, most often reported following breast reductions and reconstructions. The authors present a case of PG that developed in a 56-year-old patient, with a history of essential thrombocytosis, following mastopexy. Her significant full-thickness skin loss was successfully treated with steroids and then reconstructed via serial applications of porcine placental extracellular matrix grafts. Her wounds were completely healed in 3.5 months for the left, and 5 months for the right breast. To the best of the author's knowledge, this is the first published case in which placental grafts have been successfully used to reconstruct pyoderma wounds of the breast. Given their advantageous scarring and lack of donor-site morbidity, placental grafts should be considered for all breast surgery patients afflicted by PG.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Level of Evidence: 5<\/jats:title>\n                  <jats:p\/>\n               <\/jats:sec>","DOI":"10.1093\/asjof\/ojad085","type":"journal-article","created":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T14:21:03Z","timestamp":1694874063000},"source":"Crossref","is-referenced-by-count":3,"title":["Novel Use of Wound Matrix in Mastopexy Complicated by Pyoderma Gangrenosum"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1021-0952","authenticated-orcid":false,"given":"Louisa B","family":"Ragsdale","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz","family":"Sarhaddi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Nathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,16]]},"reference":[{"issue":"2","key":"2023101215143459500_ojad085-B1","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1177\/1090820X10366011","article-title":"A novel approach to the management of pyoderma gangrenosum complicating reduction mammaplasty","volume":"30","author":"Goshtasby","year":"2010","journal-title":"Aesthet Surg J"},{"issue":"3","key":"2023101215143459500_ojad085-B2","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.bjps.2014.12.036","article-title":"A systematic review of post-surgical pyoderma gangrenosum: identification of risk factors and proposed management strategy","volume":"68","author":"Zuo","year":"2015","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"4","key":"2023101215143459500_ojad085-B3","doi-asserted-by":"publisher","first-page":"e4282","DOI":"10.1097\/GOX.0000000000004282","article-title":"The management of postsurgical pyoderma gangrenosum following breast surgery","volume":"10","author":"Edinger","year":"2022","journal-title":"Plast Reconstr Surg Glob Open"},{"issue":"11","key":"2023101215143459500_ojad085-B4","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1111\/j.1365-4632.2004.02128.x","article-title":"Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria","volume":"43","author":"Su","year":"2004","journal-title":"Int J Dermatol"},{"issue":"6","key":"2023101215143459500_ojad085-B5","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1016\/j.jaad.2019.09.032","article-title":"Pyoderma gangrenosum in 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Surg"},{"key":"2023101215143459500_ojad085-B12","first-page":"51","article-title":"Superficial granulomatous pyoderma gangrenosum as a complication in mammoplasty","volume":"37","author":"Gonzalez de Vicente","year":"2011","journal-title":"Ciruga Plastica Ibero Latinoamericana"},{"issue":"4","key":"2023101215143459500_ojad085-B13","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1080\/00015458.2007.11680088","article-title":"Post-surgical pyoderma gangrenosum: a clinical entity","volume":"107","author":"Ouazzani","year":"2007","journal-title":"Acta Chir Belg"},{"issue":"3","key":"2023101215143459500_ojad085-B14","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1111\/j.1742-4801.2004.00059.x","article-title":"Pyoderma gangrenosum: a challenging complication of bilateral mastopexy","volume":"1","author":"Poucke","year":"2004","journal-title":"Int Wound 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