{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:13:44Z","timestamp":1787008424400,"version":"build-2736575974"},"reference-count":9,"publisher":"Informa UK Limited","issue":"2","license":[{"start":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T00:00:00Z","timestamp":1635120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Marutomo Corporation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,24]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>In the course of our research on the structure\u2013activity relationship of 5,6-dihydro-2H-pyran-2-one, (S)-6-[(R)-2-hydroxy-6-(4-fluorophenyl)hexyl]-5,6-dihydro-2H-pyran-2-one was found to show 2-3-fold more potent plant growth inhibitory activity against Italian ryegrass shoots (IC50\u00a0=\u00a095 \u00b5m) and roots (IC50\u00a0=\u00a017\u2009\u00b5m) than compound bearing unsubstituted phenyl group. The small and electron withdrawing atom at 4-position of the benzene ring caused the higher activity.<\/jats:p>","DOI":"10.1093\/bbb\/zbab185","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T10:07:02Z","timestamp":1635156422000},"page":"165-169","source":"Crossref","is-referenced-by-count":1,"title":["Structure\u2013activity relationship of the aromatic moiety of 6-substituted 5,6-dihydro-2\n                    <i>H<\/i>\n                    -pyran-2-one to find the novel compound showing higher plant growth inhibitory activity"],"prefix":"10.1080","volume":"86","author":[{"given":"Ryota","family":"Ochi","sequence":"first","affiliation":[{"name":"Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"Yoneyama","sequence":"additional","affiliation":[{"name":"Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, 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