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In this study, hair growth was enhanced by daily oral ingestion of salmon nasal cartilage proteoglycan (PG) in mice. Proteoglycan stimulated vesicular endothelial growth factor production in human follicle dermal papilla cells through insulin growth factor-1 receptor signaling, suggesting the possibility of hair loss improvement by PG ingestion.<\/jats:p>","DOI":"10.1093\/bbb\/zbad149","type":"journal-article","created":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T07:29:50Z","timestamp":1698305390000},"page":"107-110","source":"Crossref","is-referenced-by-count":3,"title":["Salmon nasal cartilage proteoglycan stimulates hair growth"],"prefix":"10.1093","volume":"88","author":[{"given":"Akio","family":"Nakane","sequence":"first","affiliation":[{"name":"Department of Biopolymer and Health Science, Hirosaki University Graduate School of Medicine , Hirosaki, Aomori , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shouhei","family":"Hirose","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Hirosaki University Graduate School of 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