{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:05:50Z","timestamp":1784041550606,"version":"3.55.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Screening of Indonesian microbial extracts identified Cosmospora sp. BioMCC-f.T-7332 as a source of Mycobacterium tuberculosis shikimate kinase (MtSK) inhibitors. A mixture of alkylated glycodidepsides TPI-1 and TPI-2 was obtained as the inhibitor (IC50\u00a0=\u00a01.5\u00a0\u00b5g\/mL) with low cytotoxicity. Although improvements in cell permeability are necessary, didepsides may serve as starting points for the development of antitubercular agents targeting MtSK.<\/jats:p>","DOI":"10.1093\/bbb\/zbag103","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T11:24:37Z","timestamp":1783941877000},"source":"Crossref","is-referenced-by-count":0,"title":["<i>Mycobacterium tuberculosis<\/i>\n                    shikimate kinase inhibitory activity of a glycodidepside mixture from\n                    <i>Cosmospora<\/i>\n                    sp. 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