{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T11:11:44Z","timestamp":1648725104614},"reference-count":72,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T00:00:00Z","timestamp":1511913600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,11,26]]},"DOI":"10.1093\/bfgp\/elx040","type":"journal-article","created":{"date-parts":[[2017,11,20]],"date-time":"2017-11-20T20:12:03Z","timestamp":1511208723000},"page":"428-440","source":"Crossref","is-referenced-by-count":2,"title":["A review of computational approaches for analysis of hepatitis C virus-mediated liver diseases"],"prefix":"10.1093","volume":"17","author":[{"given":"Sumanta","family":"Ray","sequence":"first","affiliation":[{"name":"Department of Computer Science and Engineering, Aliah University, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ujjwal","family":"Maulik","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering, Jadavpur University, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anirban","family":"Mukhopadhyay","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering, University of Kalyani, Kalyani, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,11,29]]},"reference":[{"key":"key\n\t\t\t\t2018112600524994800_elx040-B1","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.jhep.2006.07.011","article-title":"Insulin resistance and hcv: will new knowledge modify clinical management","volume":"45","author":"Negro","year":"2006","journal-title":"J Hepatol"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B2","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nrmicro1645","article-title":"Replication of hepatitis C virus","volume":"5","author":"Moradpour","year":"2007","journal-title":"Nat Rev Microbiol"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B3","first-page":"3939","article-title":"Comparison of gene expression profiles between hepatitis b virus- and hepatitis c virus-infected hepatocellular carcinoma by oligonucleotide microarray data on the basis of a supervised learning method","volume":"62","author":"Iizuka","year":"2002","journal-title":"Cancer Res"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B4","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1002\/hep.21383","article-title":"Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C","volume":"44","author":"Honda","year":"2006","journal-title":"Hepatology"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B5","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2119\/molmed.2008.00110","article-title":"Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma","volume":"15","author":"Mas","year":"2009","journal-title":"Mol Med"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B6","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1093\/jmcb\/mjs011","article-title":"Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma","volume":"4","author":"He","year":"2012","journal-title":"J Mol Cell Biol"},{"issue":"6","key":"key\n\t\t\t\t2018112600524994800_elx040-B7","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1111\/j.1349-7006.2010.01549.x","article-title":"Identification of genes preferentially methylated in hepatitis C virus-related hepatocellular carcinoma","volume":"101","author":"Deng","year":"2010","journal-title":"Cancer Sci"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B8","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/hep.25649","article-title":"Proteome and computational analyses reveal new insights into the mechanisms of hepatitis c virus-mediated liver disease posttransplantation","volume":"56","author":"Diamond","year":"2012","journal-title":"Hepatology"},{"issue":"4","key":"key\n\t\t\t\t2018112600524994800_elx040-B9","doi-asserted-by":"crossref","first-page":"e35510","DOI":"10.1371\/journal.pone.0035510","article-title":"Functional and topological properties in hepatocellular carcinoma transcriptome","volume":"7","author":"Drozdov","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B10","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/hep.21467","article-title":"Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets","volume":"45","author":"Boyault","year":"2007","journal-title":"Hepatology"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3892\/mmr.2014.2695","article-title":"Co-expression analysis of differentially expressed genes in hepatitis C virus-induced hepatocellular carcinoma","volume":"11","author":"Song","year":"2015","journal-title":"Mol Med Rep"},{"issue":"7","key":"key\n\t\t\t\t2018112600524994800_elx040-B12","doi-asserted-by":"crossref","first-page":"e22426","DOI":"10.1371\/journal.pone.0022426","article-title":"A systems biology-based classifier for hepatocellular carcinoma diagnosis","volume":"6","author":"Zhang","year":"2011","journal-title":"PLoS One"},{"issue":"3","key":"key\n\t\t\t\t2018112600524994800_elx040-B13","doi-asserted-by":"crossref","first-page":"e34240","DOI":"10.1371\/journal.pone.0034240","article-title":"Associations between HIV and human pathways revealed by protein-protein interactions and correlated gene expression profiles","volume":"7","author":"Chen","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B14","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1002\/hep.21622","article-title":"Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma","volume":"45","author":"Wurmbach","year":"2007","journal-title":"Hepatology"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B15","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1136\/gut.2008.166348","article-title":"Gene expression and hepatitis C virus infection","volume":"58","author":"Asselah","year":"2009","journal-title":"Gut"},{"issue":"4","key":"key\n\t\t\t\t2018112600524994800_elx040-B16","doi-asserted-by":"crossref","first-page":"e0153882","DOI":"10.1371\/journal.pone.0153882","article-title":"Hepatitis C virus protein interaction network analysis based on hepatocellular carcinoma","volume":"11","author":"Han","year":"2016","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B17","doi-asserted-by":"crossref","first-page":"D669","DOI":"10.1093\/nar\/gkn739","article-title":"VirusMINT: a viral protein interaction database","volume":"37","author":"Chatr-aryamontri","year":"2009","journal-title":"Nucleic Acids Res"},{"issue":"8","key":"key\n\t\t\t\t2018112600524994800_elx040-B18","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1016\/j.meegid.2011.09.001","article-title":"HCVpro: hepatitis C virus protein interaction database","volume":"11","author":"Kwofie","year":"2011","journal-title":"Infect Genet Evol"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B19","doi-asserted-by":"crossref","first-page":"D816","DOI":"10.1093\/nar\/gks1158","article-title":"The biogrid interaction database: 2013 update","volume":"41","author":"Chatr-Aryamontri","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B20","doi-asserted-by":"crossref","first-page":"D857","DOI":"10.1093\/nar\/gkr930","article-title":"MINT, the molecular interaction database: 2012 update","volume":"40","author":"Licata","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B21","doi-asserted-by":"crossref","first-page":"D447","DOI":"10.1093\/nar\/gku1003","article-title":"STRING v10: protein-protein interaction networks, integrated over the tree of life","volume":"43","author":"Szklarczyk","year":"2015","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"key\n\t\t\t\t2018112600524994800_elx040-B22","doi-asserted-by":"crossref","first-page":"e36005","DOI":"10.5812\/hepatmon.36005","article-title":"How hepatitis C virus leads to hepatocellular carcinoma: a network-based study","volume":"16","author":"Poortahmasebi","year":"2016","journal-title":"Hepat Mon"},{"issue":"1","key":"key\n\t\t\t\t2018112600524994800_elx040-B23","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1093\/nar\/29.1.242","article-title":"BIND: the biomolecular interaction network database","volume":"29","author":"Bader","year":"2001","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B24","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/nar\/30.1.303","article-title":"DIP, the database of interacting proteins: a research tool for studying cellular networks of protein interactions","volume":"30","author":"Xenarios","year":"2002","journal-title":"Nucleic Acids Research"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B25","first-page":"269","article-title":"GeneRIF quality assurance as summary revision","volume":"30","author":"Lu","year":"2007","journal-title":"Pac Symp Biocomput"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B26","doi-asserted-by":"crossref","first-page":"D497","DOI":"10.1093\/nar\/gkh070","article-title":"Human protein reference database as a discovery resource for proteomic","volume":"32","author":"Peri","year":"2004","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B27","doi-asserted-by":"crossref","first-page":"D358","DOI":"10.1093\/nar\/gkt1115","article-title":"The MIntACT project? IntACT as a common curation platform for 11 molecular interaction databases","volume":"42","author":"Orchard","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B28","doi-asserted-by":"crossref","first-page":"D691","DOI":"10.1093\/nar\/gkq1018","article-title":"Reactome: a database of reactions, pathways and biological processes","volume":"39","author":"Croft","year":"2011","journal-title":"Nucleic Acids Res"},{"issue":"8","key":"key\n\t\t\t\t2018112600524994800_elx040-B29","first-page":"S14","article-title":"Evaluation of liver cirrhosis and hepatocellular carcinoma using protein-protein interaction networks","volume":"9","author":"Ehsani Ardakani","year":"2016","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B30","doi-asserted-by":"crossref","first-page":"D767","DOI":"10.1093\/nar\/gkn892","article-title":"Human protein reference database: 2009 update","volume":"37","author":"Keshava Prasad","year":"2009","journal-title":"Nucleic Acids Res"},{"issue":"10","key":"key\n\t\t\t\t2018112600524994800_elx040-B31","doi-asserted-by":"crossref","first-page":"5404","DOI":"10.1128\/JVI.02529-09","article-title":"Gene expression profiling indicates the roles of host oxidative stress, apoptosis, lipid metabolism, and intracellular transport genes in the replication of hepatitis C virus","volume":"84","author":"Blackham","year":"2010","journal-title":"J Virol"},{"issue":"6","key":"key\n\t\t\t\t2018112600524994800_elx040-B32","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1091\/mbc.02-02-0023","article-title":"Gene expression patterns in human liver cancers","volume":"13","author":"Chen","year":"2002","journal-title":"Mol Biol Cell"},{"issue":"16","key":"key\n\t\t\t\t2018112600524994800_elx040-B33","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1038\/onc.2010.36","article-title":"Viral hepatocarcinogenesis","volume":"29","author":"Tsai","year":"2010","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B34","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.canlet.2010.11.014","article-title":"Hepatitis B and C virus hepatocarcinogenesis: lessons learned and future challenges","volume":"305","author":"Bouchard","year":"2011","journal-title":"Cancer Lett"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B35","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1093\/bioinformatics\/btm563","article-title":"Defining clusters from a hierarchical cluster tree: the dynamic tree cut package for R","volume":"24","author":"Langfelder","year":"2008","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B36","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1161\/CIRCGENETICS.110.941757","article-title":"Gene coexpression network topology of cardiac development, hypertrophy, and failure","volume":"4","author":"Dewey","year":"2011","journal-title":"Circ Cardiovasc Genet"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B37","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.prp.2009.11.006","article-title":"Gene expression patterns distinguish breast carcinomas from normal breast tissues: the Malaysian context","volume":"206","author":"Pau Ni","year":"2010","journal-title":"Pathol Res Pract"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B38","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1186\/1471-2105-7-387","article-title":"On the statistical assessment of classifiers using DNA microarray data","volume":"7","author":"Ancona","year":"2006","journal-title":"BMC Bioinformatic"},{"issue":"1","key":"key\n\t\t\t\t2018112600524994800_elx040-B39","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1093\/bioinformatics\/btn354","article-title":"The wisdom of the commons: ensemble tree classifiers for prostate cancer prognosis","volume":"25","author":"Koziol","year":"2009","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B40","doi-asserted-by":"crossref","first-page":"6062","DOI":"10.1073\/pnas.0400782101","article-title":"A gene atlas of the mouse and human protein-encoding transcriptomes","volume":"101","author":"Su","year":"2004","journal-title":"Proc Natl Acad Sci"},{"issue":"3","key":"key\n\t\t\t\t2018112600524994800_elx040-B41","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.tig.2007.12.007","article-title":"The impact of next-generation sequencing technology on genetics","volume":"24","author":"Mardis","year":"2008","journal-title":"Trends Genet"},{"issue":"1","key":"key\n\t\t\t\t2018112600524994800_elx040-B42","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nrg2484","article-title":"RNA-seq: a revolutionary tool for transcriptomics","volume":"10","author":"Wang","year":"2009","journal-title":"Nat Rev Genet"},{"issue":"6","key":"key\n\t\t\t\t2018112600524994800_elx040-B43","doi-asserted-by":"crossref","first-page":"e01500-15","DOI":"10.1128\/mBio.01500-15","article-title":"Transcriptomic analysis of chronic hepatitis B and C and liver cancer reveals MicroRNA-mediated control of cholesterol synthesis programs","volume":"6","author":"Selitsky","year":"2015","journal-title":"MBio"},{"issue":"1","key":"key\n\t\t\t\t2018112600524994800_elx040-B44","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.gendis.2015.01.001","article-title":"MicroRNAs: role in hepatitis C virus pathogenesis","volume":"2","author":"Shrivastava","year":"2015","journal-title":"Genes Dis"},{"issue":"8","key":"key\n\t\t\t\t2018112600524994800_elx040-B45","doi-asserted-by":"crossref","first-page":"3193","DOI":"10.1073\/pnas.1012464108","article-title":"Masking the 5' terminal nucleotides of the hepatitis c virus genome by an unconventional microRNA-target RNA complex","volume":"108","author":"Machlin","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5740","key":"key\n\t\t\t\t2018112600524994800_elx040-B46","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1126\/science.1113329","article-title":"Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA","volume":"309","author":"Jopling","year":"2005","journal-title":"Science"},{"issue":"17","key":"key\n\t\t\t\t2018112600524994800_elx040-B47","doi-asserted-by":"crossref","first-page":"7716","DOI":"10.1093\/nar\/gkr426","article-title":"mir-122 activates hepatitis c virus translation by a specialized mechanism requiring particular RNA components","volume":"39","author":"Roberts","year":"2011","journal-title":"Nucleic Acids Res"},{"issue":"10","key":"key\n\t\t\t\t2018112600524994800_elx040-B48","doi-asserted-by":"crossref","first-page":"e26168","DOI":"10.1371\/journal.pone.0026168","article-title":"RNA-seq analyses generate comprehensive transcriptomic landscape and reveal complex transcript patterns in hepatocellular carcinoma","volume":"6","author":"Huang","year":"2011","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B49","doi-asserted-by":"crossref","first-page":"29258","DOI":"10.1038\/srep29258","article-title":"Identification and validation of HCC-specific gene transcriptional signature for tumor antigen discovery","volume":"6","author":"Petrizzo","year":"2016","journal-title":"Sci Rep"},{"issue":"9","key":"key\n\t\t\t\t2018112600524994800_elx040-B50","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1101\/gr.154492.113","article-title":"Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma","volume":"23","author":"Kan","year":"2013","journal-title":"Genome Res"},{"issue":"1","key":"key\n\t\t\t\t2018112600524994800_elx040-B51","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang","year":"2009","journal-title":"Nat Protoc"},{"issue":"6","key":"key\n\t\t\t\t2018112600524994800_elx040-B52","doi-asserted-by":"crossref","first-page":"e88","DOI":"10.1371\/journal.pgen.0020088","article-title":"Why do hubs tend to be essential in protein networks?","volume":"2","author":"He","year":"2006","journal-title":"PLoS Genet"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B53","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/cmi.2013.37","article-title":"The role of chemokines in acute and chronic hepatitis C infection","volume":"11","author":"Fahey","year":"2014","journal-title":"Cell Mol Immunol"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B54","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/msb.2008.66","article-title":"Hepatitis C virus infection protein network","volume":"4","author":"de Chassey","year":"2008","journal-title":"Mol Syst Biol"},{"issue":"4","key":"key\n\t\t\t\t2018112600524994800_elx040-B55","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.ajhg.2008.02.013","article-title":"Walking the interactome for prioritization of candidate disease genes","volume":"82","author":"Kohler","year":"2008","journal-title":"Am J Hum Genet"},{"issue":"7","key":"key\n\t\t\t\t2018112600524994800_elx040-B56","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/nrc839","article-title":"The phosphatidylinositol 3-kinase AKT pathway in human cancer","volume":"2","author":"Vivanco","year":"2002","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"key\n\t\t\t\t2018112600524994800_elx040-B57","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1158\/1535-7163.MCT-06-0561","article-title":"Deactivation of AKT and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod","volume":"6","author":"Choudhari","year":"2007","journal-title":"Mol Cancer Ther"},{"issue":"4","key":"key\n\t\t\t\t2018112600524994800_elx040-B58","doi-asserted-by":"crossref","first-page":"e94029","DOI":"10.1371\/journal.pone.0094029","article-title":"Network-based study reveals potential infection pathways of hepatitis-C leading to various diseases","volume":"9","author":"Mukhopadhyay","year":"2014","journal-title":"PLoS One"},{"issue":"7","key":"key\n\t\t\t\t2018112600524994800_elx040-B59","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1111\/j.1572-0241.2005.41403.x","article-title":"Insulin resistance plays a significant role in liver fibrosis in chronic hepatitis C and in the response to antiviral therapy","volume":"100","author":"D'Souza","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B60","doi-asserted-by":"crossref","first-page":"7075","DOI":"10.3748\/wjg.v12.i44.7075","article-title":"Insulin resistance and hepatitis C","volume":"12","author":"Romero-G\u00f3mez","year":"2006","journal-title":"World J Gastroenterol"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B61","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1053\/gast.2002.33023","article-title":"Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C","volume":"122","author":"Poynard","year":"2002","journal-title":"Gastroenterology"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B62","doi-asserted-by":"crossref","first-page":"S59","DOI":"10.1038\/sj.cdd.4401163","article-title":"Hepatitis C and liver fibrosis","volume":"10","author":"Schuppan","year":"2003","journal-title":"Cell Death Differ"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B63","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1158\/0008-5472.CAN-07-0008","article-title":"BCL6 represses Smad signaling in transforming growth factor-beta resistance","volume":"68","author":"Wang","year":"2008","journal-title":"Cancer Res"},{"issue":"12","key":"key\n\t\t\t\t2018112600524994800_elx040-B64","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1038\/nrd2656","article-title":"The genetics of the p53 pathway, apoptosis and cancer therapy","volume":"7","author":"Vazquez","year":"2008","journal-title":"Nat Rev Drug Discov"},{"issue":"13","key":"key\n\t\t\t\t2018112600524994800_elx040-B65","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1093\/bioinformatics\/btm158","article-title":"Weighted rank aggregation of cluster validation measures: a Monte Carlo cross-entropy approach","volume":"23","author":"Pihur","year":"2007","journal-title":"Bioinformatics"},{"issue":"6","key":"key\n\t\t\t\t2018112600524994800_elx040-B66","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1053\/j.gastro.2013.08.055","article-title":"Genome-wide methylation analysis and epigenetic unmasking identify tumor suppressor genes in hepatocellular carcinoma","volume":"145","author":"Revill","year":"2013","journal-title":"Gastroenterology"},{"key":"key\n\t\t\t\t2018112600524994800_elx040-B67","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1752-0509-7-S5-S2","article-title":"Dynamic protein interaction modules in human hepatocellular carcinoma progression","volume":"7","author":"Yu","year":"2013","journal-title":"BMC Syst Biol"},{"issue":"6","key":"key\n\t\t\t\t2018112600524994800_elx040-B68","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/eci.12441","article-title":"The Ras\/MAPK pathway and hepatocarcinoma: pathogenesis and therapeutic implications","volume":"45","author":"Delire","year":"2015","journal-title":"Eur J Clin Invest"},{"issue":"4","key":"key\n\t\t\t\t2018112600524994800_elx040-B69","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1002\/hep.510270409","article-title":"Activation of mitogen-activated protein kinases\/extracellular signal-regulated kinases in human hepatocellular carcinoma","volume":"27","author":"Ito","year":"1998","journal-title":"Hepatology"},{"issue":"5","key":"key\n\t\t\t\t2018112600524994800_elx040-B70","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.3892\/ol.2016.5110","article-title":"The Ras\/Raf\/MEK\/ERK signaling pathway and its role in the occurrence and development of HCC","volume":"12","author":"Li","year":"2016","journal-title":"Oncol Lett"},{"issue":"5","key":"key\n\t\t\t\t2018112600524994800_elx040-B71","doi-asserted-by":"crossref","first-page":"e1004163","DOI":"10.1371\/journal.ppat.1004163","article-title":"Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle","volume":"10","author":"Li","year":"2014","journal-title":"PLoS Pathog"},{"issue":"38","key":"key\n\t\t\t\t2018112600524994800_elx040-B72","doi-asserted-by":"crossref","first-page":"16410","DOI":"10.1073\/pnas.0907439106","article-title":"A genome-wide genetic screen for host factors required for hepatitis C virus propagation","volume":"106","author":"Li","year":"2009","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Briefings in Functional Genomics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/bfg\/article-pdf\/17\/6\/428\/26706477\/elx040.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,6]],"date-time":"2019-10-06T10:53:51Z","timestamp":1570359231000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bfg\/article\/17\/6\/428\/4675067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,29]]},"references-count":72,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2017,11,29]]},"published-print":{"date-parts":[[2018,11,26]]}},"URL":"https:\/\/doi.org\/10.1093\/bfgp\/elx040","relation":{},"ISSN":["2041-2649","2041-2657"],"issn-type":[{"value":"2041-2649","type":"print"},{"value":"2041-2657","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,11]]},"published":{"date-parts":[[2017,11,29]]}}}