{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T13:13:34Z","timestamp":1783430014715,"version":"3.54.6"},"reference-count":58,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:00:00Z","timestamp":1783382400000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Traditional, knowledge-driven pathway annotations and bulk transcriptomic analyses often fail to capture the cellular specificity and mechanistic heterogeneity of immune responses. We present scImmuneCo, a comprehensive resource of immune cell-specific co-expression modules derived from single-cell RNA sequencing across 17 immunological conditions and 1.78 million cells. Using a modified graph-based framework, we constructed 873 robust modules spanning 7 major immune cell types, providing stable, cell-type-specific interaction networks for functional inference. scImmuneCo resolves complex biology at cellular resolution. We identify 20 interferon-related modules that reveal both conserved and cell-type-specific regulatory programs, clarifying disease-dependent differences that are invisible to pathway tools treating interferon signaling as a unitary process. We also uncover age-associated CD8+ T cell programs, capturing state transitions from naive to effector\/memory cells and exposing a progressive imbalance in translation and cytotoxicity with age. Together, these results demonstrate the power of high-resolution, data-driven functional inference to link gene groups to biological roles and disease processes. To support broad application, we provide an R package (https:\/\/github.com\/FrankQYW\/scImmuneCo_R) for module-based analysis of both single-cell and bulk transcriptomic data, along with an interactive web portal (http:\/\/www.scimmuneco.site\/) for visualization and gene-module exploration. scImmuneCo offers a scalable and interpretable framework for dissecting immune mechanisms and identifying disease-relevant transcriptional programs with cellular resolution.<\/jats:p>","DOI":"10.1093\/bib\/bbag366","type":"journal-article","created":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:13:29Z","timestamp":1783426409000},"source":"Crossref","is-referenced-by-count":0,"title":["scImmuneCo: a compendium of cell-type-specific functional modules for decoding immune responses from single-cell RNA-seq data"],"prefix":"10.1093","volume":"27","author":[{"given":"Frank Qingyun","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, The University of Hong Kong , 21 Sassoon Road, Pokfulam, Hong Kong, 999077 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caicai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, The University of Hong Kong , 21 Sassoon Road, Pokfulam, Hong Kong, 999077 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, The University of Hong Kong , 21 Sassoon Road, Pokfulam, Hong Kong, 999077 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huidong","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, The University of Hong Kong , 21 Sassoon Road, Pokfulam, Hong Kong, 999077 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, The University of Hong Kong , 21 Sassoon Road, Pokfulam, Hong Kong, 999077 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youming","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, The University of Hong Kong , 21 Sassoon Road, Pokfulam, Hong Kong, 999077 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, The University of Hong Kong , 21 Sassoon Road, Pokfulam, Hong Kong, 999077 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0063-6327","authenticated-orcid":false,"given":"Wanling","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, The University of Hong Kong , 21 Sassoon Road, Pokfulam, Hong Kong, 999077 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,7]]},"reference":[{"key":"2026070708085852300_ref1","doi-asserted-by":"publisher","first-page":"110367","DOI":"10.1016\/j.clim.2024.110367","article-title":"Transcriptomic studies unravel the molecular and cellular complexity of systemic lupus erythematosus: a review","volume":"268","author":"Wang","year":"2024","journal-title":"Clin Immunol"},{"key":"2026070708085852300_ref2","doi-asserted-by":"publisher","DOI":"10.3390\/genes13071168","article-title":"Salnikova LE: genes and diseases: insights from transcriptomics studies","volume":"13","author":"Kolobkov","year":"2022","journal-title":"Genes (Basel)"},{"key":"2026070708085852300_ref3","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1101\/gr.265249.120","article-title":"Multi-cell type gene coexpression network analysis reveals coordinated interferon response and cross-cell type correlations in systemic lupus erythematosus","volume":"31","author":"Panwar","year":"2021","journal-title":"Genome Res"},{"key":"2026070708085852300_ref4","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1186\/s12967-021-02914-2","article-title":"The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML","volume":"19","author":"Guo","year":"2021","journal-title":"J Transl Med"},{"key":"2026070708085852300_ref5","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.immuni.2008.05.012","article-title":"A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus","volume":"29","author":"Chaussabel","year":"2008","journal-title":"Immunity"},{"key":"2026070708085852300_ref6","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1038\/nature09247","article-title":"An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis","volume":"466","author":"Berry","year":"2010","journal-title":"Nature"},{"key":"2026070708085852300_ref7","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-24584-w","article-title":"Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data","volume":"12","author":"Altman","year":"2021","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref8","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1038\/ni.2789","article-title":"Molecular signatures of antibody responses derived from a systems biology study of five human vaccines","volume":"15","author":"Li","year":"2014","journal-title":"Nat Immunol"},{"key":"2026070708085852300_ref9","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1016\/j.cell.2016.05.057","article-title":"Personalized Immunomonitoring uncovers molecular networks that stratify lupus patients (vol 165, pg 551, 2016)","volume":"165","author":"Banchereau","year":"2016","journal-title":"Cell"},{"key":"2026070708085852300_ref10","doi-asserted-by":"publisher","first-page":"2497","DOI":"10.1016\/j.immuni.2024.09.004","article-title":"Type I IFN drives unconventional IL-1beta secretion in lupus monocytes","volume":"57","author":"Caielli","year":"2024","journal-title":"Immunity"},{"key":"2026070708085852300_ref11","doi-asserted-by":"publisher","first-page":"1980","DOI":"10.1038\/s41467-021-22312-y","article-title":"Type I interferons affect the metabolic fitness of CD8(+) T cells from patients with systemic lupus erythematosus","volume":"12","author":"Buang","year":"2021","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref12","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1038\/s41590-020-0743-0","article-title":"Mapping systemic lupus erythematosus heterogeneity at the single-cell level","volume":"21","author":"Nehar-Belaid","year":"2020","journal-title":"Nat Immunol"},{"key":"2026070708085852300_ref13","doi-asserted-by":"publisher","first-page":"594658","DOI":"10.3389\/fimmu.2020.594658","article-title":"Single-cell RNA sequencing reveals the expansion of cytotoxic CD4(+) T lymphocytes and a landscape of immune cells in primary Sjogren\u2019s syndrome","volume":"11","author":"Hong","year":"2020","journal-title":"Front Immunol"},{"key":"2026070708085852300_ref14","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1038\/s41467-019-14118-w","article-title":"Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis","volume":"11","author":"Schafflick","year":"2020","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref15","doi-asserted-by":"publisher","first-page":"e2204289119","DOI":"10.1073\/pnas.2204289119","article-title":"Single-cell analyses highlight the proinflammatory contribution of C1q-high monocytes to Behcet's disease","volume":"119","author":"Zheng","year":"2022","journal-title":"Proc Natl Acad Sci USA"},{"key":"2026070708085852300_ref16","doi-asserted-by":"publisher","DOI":"10.1172\/JCI166741","article-title":"Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis","volume":"133","author":"Verweyen","year":"2023","journal-title":"J Clin Invest"},{"key":"2026070708085852300_ref17","doi-asserted-by":"publisher","first-page":"5838","DOI":"10.1016\/j.cell.2021.10.023","article-title":"COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas","volume":"184","author":"Ren","year":"2021","journal-title":"Cell"},{"key":"2026070708085852300_ref18","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1002\/JLB.5MA0721-825R","article-title":"Dynamic changes in human single-cell transcriptional signatures during fatal sepsis","volume":"110","author":"Qiu","year":"2021","journal-title":"J Leukoc Biol"},{"key":"2026070708085852300_ref19","doi-asserted-by":"publisher","first-page":"7387","DOI":"10.1038\/s41467-023-43181-7","article-title":"Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets","volume":"14","author":"Dooley","year":"2023","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref20","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1038\/s43588-023-00523-1","article-title":"Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data (vol 3, pg 644, 2023)","volume":"3","author":"Chen","year":"2023","journal-title":"Nat Comput Sci"},{"key":"2026070708085852300_ref21","doi-asserted-by":"publisher","first-page":"5444","DOI":"10.1038\/s41467-021-25771-5","article-title":"Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients","volume":"12","author":"Wang","year":"2021","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref22","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1016\/j.jaci.2022.04.027","article-title":"Single-cell analysis implicates T(H)17-to-T(H)2 cell plasticity in the pathogenesis of palmoplantar pustulosis","volume":"150","author":"McCluskey","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"2026070708085852300_ref23","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s13402-023-00853-2","article-title":"Single-cell transcriptomic profiling reveals immune cell heterogeneity in acute myeloid leukaemia peripheral blood mononuclear cells after chemotherapy","volume":"47","author":"Hu","year":"2024","journal-title":"Cell Oncol"},{"key":"2026070708085852300_ref24","doi-asserted-by":"publisher","first-page":"4977","DOI":"10.1038\/s41467-021-25246-7","article-title":"Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis","volume":"12","author":"Wu","year":"2021","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref25","doi-asserted-by":"publisher","first-page":"5789","DOI":"10.1038\/s41467-023-41328-0","article-title":"Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis","volume":"14","author":"Nishide","year":"2023","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref26","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1038\/s42003-024-06225-2","article-title":"Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients","volume":"7","author":"Vrij","year":"2024","journal-title":"Commun Biol"},{"key":"2026070708085852300_ref27","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29450-x","article-title":"Single-cell atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses","volume":"13","author":"Rodr\u00edguez-Ubreva","year":"2022","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref28","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.immuni.2023.12.014","article-title":"Single-cell atlas of healthy human blood unveils age-related loss of NKG2C GZMB CD8 memory T cells and accumulation of type 2 memory T cells (vol 56, pg 2836, 2023)","volume":"57","author":"Terekhova","year":"2024","journal-title":"Immunity"},{"key":"2026070708085852300_ref29","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1038\/s41587-023-01767-y","article-title":"Dictionary learning for integrative, multimodal and scalable single-cell analysis","volume":"42","author":"Hao","year":"2024","journal-title":"Nat Biotechnol"},{"key":"2026070708085852300_ref30","doi-asserted-by":"publisher","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"2026070708085852300_ref31","doi-asserted-by":"publisher","first-page":"4846","DOI":"10.1038\/s41467-023-40503-7","article-title":"Cell-type-specific co-expression inference from single cell RNA-sequencing data","volume":"14","author":"Su","year":"2023","journal-title":"Nat Commun"},{"key":"2026070708085852300_ref32","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1186\/1471-2105-9-559","article-title":"WGCNA: an R package for weighted correlation network analysis","volume":"9","author":"Langfelder","year":"2008","journal-title":"BMC Bioinformatics"},{"key":"2026070708085852300_ref33","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1016\/j.immuni.2012.12.008","article-title":"Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines","volume":"38","author":"Obermoser","year":"2013","journal-title":"Immunity"},{"key":"2026070708085852300_ref34","doi-asserted-by":"publisher","first-page":"3292","DOI":"10.1038\/s41596-024-01020-z","article-title":"Using clusterProfiler to characterize multiomics data","volume":"19","author":"Xu","year":"2024","journal-title":"Nat Protoc"},{"key":"2026070708085852300_ref35","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf3041","article-title":"Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease","volume":"376","author":"Yazar","year":"2022","journal-title":"Science"},{"key":"2026070708085852300_ref36","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.cels.2015.12.004","article-title":"The molecular signatures database (MSigDB) hallmark gene set collection","volume":"1","author":"Liberzon","year":"2015","journal-title":"Cell Syst"},{"key":"2026070708085852300_ref37","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1471-2105-14-7","article-title":"GSVA: gene set variation analysis for microarray and RNA-seq data","volume":"14","author":"Hanzelmann","year":"2013","journal-title":"BMC Bioinformatics"},{"key":"2026070708085852300_ref38","doi-asserted-by":"publisher","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"2026070708085852300_ref39","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.smim.2014.05.004","article-title":"Regulation of NF-kappaB by TNF family cytokines","volume":"26","author":"Hayden","year":"2014","journal-title":"Semin Immunol"},{"key":"2026070708085852300_ref40","doi-asserted-by":"publisher","first-page":"17023","DOI":"10.1038\/sigtrans.2017.23","article-title":"NF-kappaB signaling in inflammation","volume":"2","author":"Liu","year":"2017","journal-title":"Signal Transduct Target Ther"},{"key":"2026070708085852300_ref41","doi-asserted-by":"publisher","first-page":"4200","DOI":"10.1128\/IAI.00593-13","article-title":"Shedding of tumor necrosis factor receptor 1 induced by protein a decreases tumor necrosis factor alpha availability and inflammation during systemic Staphylococcus aureus infection","volume":"81","author":"Giai","year":"2013","journal-title":"Infect Immun"},{"key":"2026070708085852300_ref42","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1136\/ard.2008.093146","article-title":"Lack of association between the interferon-alpha signature and longitudinal changes in disease activity in systemic lupus erythematosus","volume":"68","author":"Landolt-Marticorena","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"2026070708085852300_ref43","doi-asserted-by":"publisher","first-page":"102869","DOI":"10.1016\/j.jaut.2022.102869","article-title":"A cluster of type II interferon-regulated genes associates with disease activity in patients with systemic lupus erythematosus","volume":"132","author":"Siddiqi","year":"2022","journal-title":"J Autoimmun"},{"key":"2026070708085852300_ref44","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1002\/art.38628","article-title":"Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures","volume":"66","author":"Chiche","year":"2014","journal-title":"Arthritis Rheumatol"},{"key":"2026070708085852300_ref45","doi-asserted-by":"publisher","first-page":"D852","DOI":"10.1093\/nar\/gkn732","article-title":"INTERFEROME: the database of interferon regulated genes","volume":"37","author":"Samarajiwa","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"2026070708085852300_ref46","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.176963","article-title":"Coordinated immune dysregulation in juvenile dermatomyositis revealed by single-cell genomics","volume":"9","author":"Rabadam","year":"2024","journal-title":"JCI Insight"},{"key":"2026070708085852300_ref47","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1136\/annrheumdis-2020-218690","article-title":"Janus kinase (JAK) inhibition with baricitinib in refractory juvenile dermatomyositis","volume":"80","author":"Kim","year":"2021","journal-title":"Ann Rheum Dis"},{"key":"2026070708085852300_ref48","doi-asserted-by":"publisher","first-page":"962585","DOI":"10.3389\/fped.2022.962585","article-title":"Short-term effectiveness of baricitinib in children with refractory and\/or severe juvenile dermatomyositis","volume":"10","author":"Wang","year":"2022","journal-title":"Front Pediatr"},{"key":"2026070708085852300_ref49","doi-asserted-by":"publisher","first-page":"D1376","DOI":"10.1093\/nar\/gkaf1129","article-title":"DisCP-atlas: a comprehensive resource mapping cellular processes to complex diseases","volume":"54","author":"Wang","year":"2026","journal-title":"Nucleic Acids Res"},{"key":"2026070708085852300_ref50","doi-asserted-by":"publisher","first-page":"113026","DOI":"10.1016\/j.isci.2025.113026","article-title":"Single-cell transcriptional landscape of peripheral myeloid cells in autoimmune diseases","volume":"28","author":"Wang","year":"2025","journal-title":"iScience"},{"key":"2026070708085852300_ref51","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1186\/s13075-024-03327-4","article-title":"Unraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states","volume":"26","author":"Wang","year":"2024","journal-title":"Arthritis Res Ther"},{"key":"2026070708085852300_ref52","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1038\/s42003-019-0382-x","article-title":"Gene expression analysis delineates the potential roles of multiple interferons in systemic lupus erythematosus","volume":"2","author":"Catalina","year":"2019","journal-title":"Commun Biol"},{"key":"2026070708085852300_ref53","doi-asserted-by":"publisher","first-page":"3512","DOI":"10.1016\/j.celrep.2018.05.057","article-title":"Age-related decline in primary CD8T cell responses is associated with the development of senescence in virtual memory CD8T cells","volume":"23","author":"Quinn","year":"2018","journal-title":"Cell Rep"},{"key":"2026070708085852300_ref54","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.smim.2012.04.009","article-title":"Age-related changes in CD8 T cell homeostasis and immunity to infection","volume":"24","author":"Nikolich-Zugich","year":"2012","journal-title":"Semin Immunol"},{"key":"2026070708085852300_ref55","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1038\/s41392-023-01502-8","article-title":"Inflammation and aging: Signaling pathways and intervention therapies","volume":"8","author":"Li","year":"2023","journal-title":"Signal Transduct Target Ther"},{"key":"2026070708085852300_ref56","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/j.arr.2013.04.003","article-title":"The impact of ageing on natural killer cell function and potential consequences for health in older adults","volume":"12","author":"Hazeldine","year":"2013","journal-title":"Ageing Res Rev"},{"key":"2026070708085852300_ref57","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1182\/blood-2018-03-838946","article-title":"CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells","volume":"133","author":"DKt","year":"2019","journal-title":"Blood"},{"key":"2026070708085852300_ref58","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.cell.2009.05.045","article-title":"CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid Leukemia stem cells","volume":"138","author":"Majeti","year":"2009","journal-title":"Cell"}],"container-title":["Briefings in Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bib\/article-pdf\/27\/4\/bbag366\/68707030\/bbag366.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bib\/article-pdf\/27\/4\/bbag366\/68707030\/bbag366.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:13:30Z","timestamp":1783426410000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bib\/article\/doi\/10.1093\/bib\/bbag366\/8726034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7,3]]}},"URL":"https:\/\/doi.org\/10.1093\/bib\/bbag366","relation":{},"ISSN":["1467-5463","1477-4054"],"issn-type":[{"value":"1467-5463","type":"print"},{"value":"1477-4054","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,7]]},"published":{"date-parts":[[2026,7]]},"article-number":"bbag366"}}