{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T20:33:54Z","timestamp":1772138034039,"version":"3.50.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":257,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"German Federal Ministry of Education and Research"},{"name":"CompLS research and funding concept","award":["031L0294"],"award-info":[{"award-number":["031L0294"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Cell-type deconvolution is widely applied to gene expression and DNA methylation data, but access to methods for the latter remains limited. We introduce deconvMe, a new R package that simplifies access to DNA methylation-based deconvolution methods predominantly for blood data, and we additionally compare their estimates to those from gene expression and experimental ground truth data using a unique matched blood dataset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Availability and Implementation<\/jats:title>\n                    <jats:p>DevonMe is available at https:\/\/github.com\/omnideconv\/deconvMe, the processed blood data is available at https:\/\/figshare.com\/articles\/dataset\/methyldeconv_data\/28563854\/3.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bioadv\/vbaf201","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T11:43:51Z","timestamp":1756467831000},"source":"Crossref","is-referenced-by-count":0,"title":["Unifying DNA methylation-based\n                    <i>in silico<\/i>\n                    cell-type deconvolution with\n                    <i>deconvMe<\/i>"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8661-0453","authenticated-orcid":false,"given":"Alexander","family":"Dietrich","sequence":"first","affiliation":[{"name":"Data Science in Systems Biology, TUM School of Life Sciences, Technical University of Munich , Freising, 85354,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina-Liv","family":"Willruth","sequence":"additional","affiliation":[{"name":"Data Science in Systems Biology, TUM School of Life Sciences, Technical University of Munich , Freising, 85354,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Korbinian","family":"P\u00fcrckhauer","sequence":"additional","affiliation":[{"name":"Core Facility Microbiome, ZIEL Institute for Food & Health, Technical University of Munich , Freising, 85354,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Oltmanns","sequence":"additional","affiliation":[{"name":"Centre for Individualised Infection Medicine (CiiM), A Joint Venture between the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"TWINCORE, A Joint Venture between the Helmholtz-Centre for Infection Research (HZI) and the Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moana","family":"Witte","sequence":"additional","affiliation":[{"name":"Centre for Individualised Infection Medicine (CiiM), A Joint Venture between the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"TWINCORE, A Joint Venture between the Helmholtz-Centre for Infection Research (HZI) and the Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Klein","sequence":"additional","affiliation":[{"name":"Centre for Individualised Infection Medicine (CiiM), A Joint Venture between the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"TWINCORE, A Joint Venture between the Helmholtz-Centre for Infection Research (HZI) and the Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"CAIMed \u2013 Center for AI in Medicine, Joint Venture of Leibniz University Hannover and Hannover Medical School , Hannover, 30625,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anke R M","family":"Kraft","sequence":"additional","affiliation":[{"name":"Centre for Individualised Infection Medicine (CiiM), A Joint Venture between the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"TWINCORE, A Joint Venture between the Helmholtz-Centre for Infection Research (HZI) and the Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"Cluster of Excellence Resolving Infection Susceptibility (RESIST; EXC 2155), Hannover Medical School , Hannover, 30625,","place":["Germany"]},{"name":"German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig , Braunschweig, 38124,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Cornberg","sequence":"additional","affiliation":[{"name":"Centre for Individualised Infection Medicine (CiiM), A Joint Venture between the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"TWINCORE, A Joint Venture between the Helmholtz-Centre for Infection Research (HZI) and the Hannover Medical School (MHH) , Hannover, 30625,","place":["Germany"]},{"name":"Cluster of Excellence Resolving Infection Susceptibility (RESIST; EXC 2155), Hannover Medical School , Hannover, 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