{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T01:13:59Z","timestamp":1778721239803,"version":"3.51.4"},"reference-count":101,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"vor","delay-in-days":132,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Over the past two decades, the Student Council Symposium (SCS), the flagship event of the ISCB Student Council, has grown into a vital forum for early-career researchers in computational biology. Since its inception in 2005, the SCS has served as a platform for scientific exchange, skill development, and community building in a student-led, globally inclusive environment. The 20th edition, held in 2024 in Montr\u00e9al, Canada, continued the symposium\u2019s tradition of global engagement and hybrid accessibility, reaffirming a commitment to in-person dialogue. This article presents a comprehensive retrospective of the evolution of computational biology through the lens of SCS. We trace key advances from genome-scale analyses and structural modeling to single-cell and AI-driven bioinformatics. Based on SCS2024 talks and keynotes, we illustrate how emerging interdisciplinary methods have reshaped the field. We also highlight parallel efforts in global education, regional expansion, and equity, diversity, and inclusion initiatives. This retrospective shows how SCS has not only reflected the transformation of the field but also played a key role in shaping emerging leaders in bioinformatics.<\/jats:p>","DOI":"10.1093\/bioadv\/vbag097","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T11:29:39Z","timestamp":1774956579000},"source":"Crossref","is-referenced-by-count":0,"title":["20 Years of the ISCB Student Council Symposium: shaping computational biology and future leaders"],"prefix":"10.1093","volume":"6","author":[{"given":"Miguel","family":"Fernandez-Martin","sequence":"first","affiliation":[{"name":"Computational Biology Group, Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS) , Barcelona,","place":["Spain"]},{"name":"Evolutionary Systems Biophysics Group, Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS) , Barcelona,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Castillo-Orozco","sequence":"additional","affiliation":[{"name":"Research Institute, McGill University Health Centre (RI-MUHC) , Montreal,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Poley-Gil","sequence":"additional","affiliation":[{"name":"Computational Biology Group, Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS) , Barcelona,","place":["Spain"]},{"name":"Evolutionary Systems Biophysics Group, Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS) , Barcelona,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iria","family":"Pose-Lagoa","sequence":"additional","affiliation":[{"name":"Computational Biology Group, Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS) , Barcelona,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8064-330X","authenticated-orcid":false,"given":"Sebasti\u00e1n","family":"Urquiza-Zurich","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences, University of Chile , Santiago,","place":["Chile"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Othmane","family":"Hayoun-Mya","sequence":"additional","affiliation":[{"name":"Computational Biology Group, Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS) , Barcelona,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Machado-Reyes","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Department, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute , New York, NY,","place":["United 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Marie","family":"Boll","sequence":"additional","affiliation":[{"name":"Department, Hospital del Mar Medical Research Institute (IMIM) , Barcelona,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Garcia-Valiente","sequence":"additional","affiliation":[{"name":"MELIS Department, Pompeu Fabra University , Barcelona,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R Gonzalo","family":"Parra","sequence":"additional","affiliation":[{"name":"Evolutionary Systems Biophysics Group, Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS) , Barcelona,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1239-5962","authenticated-orcid":false,"given":"Gabriel J","family":"Olgu\u00edn-Orellana","sequence":"additional","affiliation":[{"name":"Departamento de Farmacolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Universidad de 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