{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:16:33Z","timestamp":1788308193112,"version":"build-2803163510"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"NSF","doi-asserted-by":"publisher","award":["DEB-1655571"],"award-info":[{"award-number":["DEB-1655571"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"NSF","doi-asserted-by":"publisher","award":["IOS-2307044"],"award-info":[{"award-number":["IOS-2307044"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Hybrid zones represent powerful natural systems for studying reproductive isolation and speciation. One key genomic signature of genetic incompatibilities and epistatic interactions is linkage disequilibrium (LD)\u2014non-random associations between loci from different lineage backgrounds, generated by selection against maladaptive allele combinations. However, admixture alone induces strong genome-wide LD in hybrid populations, obscuring selection-driven signals. Here, we present AdmixLD, a fast, scalable C++ tool for genome-wide LD scanning in hybrid zones that estimates LD using partial correlation to control for individual hybrid index. By removing admixture-driven covariance, AdmixLD enhances detection of locus-specific associations and enables genome-scale identification of candidate barrier loci and interacting genomic regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Availability<\/jats:title>\n                    <jats:p>The software and its code source are available at https:\/\/github.com\/yzfranci\/AdmixLD, and scripts for the data analysis are available at https:\/\/github.com\/yzfranci\/AdmixLDAnalysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btag633","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:26:10Z","timestamp":1787837170000},"source":"Crossref","is-referenced-by-count":0,"title":["AdmixLD: fast genome-scale inference of ancestry disequilibrium in hybrid zones"],"prefix":"10.1093","volume":"42","author":[{"given":"Yannick Z","family":"Francioli","sequence":"first","affiliation":[{"name":"Department of Biology, University of Texas at Arlington , Arlington, TX,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard H","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Entomology and Plant Pathology, University of Arkansas , Fayetteville, AR,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaas","family":"Ballard","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Texas at Arlington , Arlington, TX,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachariah","family":"Gompert","sequence":"additional","affiliation":[{"name":"Department of Biology, Utah State University , Logan, UT,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd A","family":"Castoe","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Texas at Arlington , Arlington, TX,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,27]]},"reference":[{"key":"2026090119564534700_btag633-B1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1420-9101.2012.02599.x","article-title":"Hybridization and speciation","volume":"26","author":"Abbott","year":"2013","journal-title":"J Evol Biol"},{"key":"2026090119564534700_btag633-B2","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nature13301","article-title":"Genetics of ecological divergence during speciation","volume":"511","author":"Arnegard","year":"2014","journal-title":"Nature"},{"key":"2026090119564534700_btag633-B3","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1146\/annurev.es.16.110185.000553","article-title":"Analysis of hybrid 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