{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T04:46:32Z","timestamp":1758343592891,"version":"3.44.0"},"reference-count":165,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T00:00:00Z","timestamp":1744588800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Shanghai Municipal Health Youth Talent","award":["2022YQ019"],"award-info":[{"award-number":["2022YQ019"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Endometriosis (EMS) is a significant contributor to female infertility, with its underlying mechanisms remaining inadequately understood. Animal models serve as essential tools for investigating disease progression and evaluating treatment options. This article reviews the advancements in research involving animal models, including nonhuman primates and rodents, in the development of EMS-related infertility models. This study provides a comprehensive overview of the latest advancements in understanding the mechanisms of infertility related to EMS in animal models. It serves as a valuable resource for researchers seeking guidance in choosing suitable animal models for investigations on the pathogenesis and pharmacological treatment of this condition.<\/jats:p>","DOI":"10.1093\/biolre\/ioaf089","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T08:27:26Z","timestamp":1744619246000},"page":"494-510","source":"Crossref","is-referenced-by-count":0,"title":["Advances in endometriosis research: animal models for the study of reproductive disorders"],"prefix":"10.1093","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9399-5232","authenticated-orcid":false,"given":"Mingjuan","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai Jiaotong University School of Medicine , 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingchen","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai Jiaotong University School of Medicine , 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xipeng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai Jiaotong University School of Medicine , 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,4,14]]},"reference":[{"key":"2025091917102978700_ref1","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1016\/j.cell.2021.04.041","article-title":"Endometriosis: Etiology, pathobiology, and therapeutic prospects","volume":"184","author":"Saunders","year":"2021","journal-title":"Cell"},{"key":"2025091917102978700_ref2","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/S0140-6736(21)00389-5","article-title":"Endometriosis is a chronic systemic disease: clinical challenges and novel innovations","volume":"397","author":"Taylor","year":"2021","journal-title":"Lancet"},{"key":"2025091917102978700_ref3","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/1471-0528.14711","article-title":"Epidemiology of endometriosis: a large population-based database study from a healthcare provider with 2 million members","volume":"125","author":"Eisenberg","year":"2018","journal-title":"BJOG"},{"key":"2025091917102978700_ref4","doi-asserted-by":"crossref","first-page":"102454","DOI":"10.1016\/j.bpobgyn.2023.102454","article-title":"Epidemiology of infertility in women with endometriosis","volume":"92","author":"Maggiore","year":"2024","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"2025091917102978700_ref5","doi-asserted-by":"crossref","first-page":"hoac009","DOI":"10.1093\/hropen\/hoac009","article-title":"ESHRE guideline: endometriosis","volume":"2022","author":"Becker","year":"2022","journal-title":"Hum Reprod Open"},{"key":"2025091917102978700_ref6","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1016\/j.fertnstert.2019.12.037","article-title":"Pregnancy outcomes in women with history of surgery for endometriosis","volume":"113","author":"Farella","year":"2020","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref7","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1093\/humrep\/dead197","article-title":"ART in Europe, 2019: results generated from European registries by ESHRE\u2020","volume":"38","author":"European IVF Monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE)","year":"2023","journal-title":"Hum Reprod"},{"key":"2025091917102978700_ref8","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1007\/s00404-016-4136-4","article-title":"The effects of surgery for endometriosis on pregnancy outcomes following in vitro fertilization and embryo transfer: a systematic review and meta-analysis","volume":"294","author":"Rossi","year":"2016","journal-title":"Arch Gynecol Obstet"},{"key":"2025091917102978700_ref9","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1111\/1471-0528.12366","article-title":"The effect of endometriosis on in vitro fertilisation outcome: a systematic review and meta-analysis","volume":"120","author":"Harb","year":"2013","journal-title":"BJOG"},{"key":"2025091917102978700_ref10","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.soscij.2010.07.012","article-title":"Ethical problems with infertility treatments: attitudes and explanations","volume":"47","author":"Shreffler","year":"2010","journal-title":"The Social Science Journal"},{"key":"2025091917102978700_ref11","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1600-0684.2010.00409.x","article-title":"Ovarian pathology in rhesus macaques: a 12-year retrospective","volume":"39","author":"Marr-Belvin","year":"2010","journal-title":"J Med Primatol"},{"key":"2025091917102978700_ref12","first-page":"11","article-title":"Disseminated endometriosis in a rhesus monkey (Macaca mulatta). Histogenesis and possible relationship to irradiation exposure 1,2","volume":"60","author":"McClure","year":"1971","journal-title":"J Med Assoc Ga"},{"key":"2025091917102978700_ref13","first-page":"597","article-title":"Spontaneous endometriosis in a cynomolgus monkey (Macaca fascicularis)","volume":"33","author":"Fanton","year":"1983","journal-title":"Lab Anim Sci"},{"key":"2025091917102978700_ref14","doi-asserted-by":"crossref","first-page":"859","DOI":"10.2460\/javma.1977.171.09.859","article-title":"Pelvic endometriosis and simian foamy virus infection in a pigtailed macaque","volume":"171","author":"DiGiacomo","year":"1977","journal-title":"J Am Vet Med Assoc"},{"key":"2025091917102978700_ref15","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/0002-9378(68)90572-3","article-title":"Spontaneous endometriosis in the Kenya baboon (Papio doguera)","volume":"101","author":"Merrill","year":"1968","journal-title":"Am J Obstet Gynecol"},{"key":"2025091917102978700_ref16","doi-asserted-by":"crossref","first-page":"403","DOI":"10.30802\/AALAS-CM-17-000112","article-title":"Acute abdominal distension due to disseminated peritoneal neoplasia in a rhesus macaque (Macaca mulatta)","volume":"68","author":"Asher","year":"2018","journal-title":"Comp Med"},{"key":"2025091917102978700_ref17","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1095\/biolreprod45.3.411","article-title":"Prevalence and laparoscopic appearance of spontaneous endometriosis in the baboon (Papio anubis, Papio cynocephalus)","volume":"45","author":"D'Hooghe","year":"1991","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref18","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1093\/humrep\/dey095","article-title":"Spontaneous endometriosis in cynomolgus monkeys as a clinically relevant experimental model","volume":"33","author":"Nishimoto-Kakiuchi","year":"2018","journal-title":"Hum Reprod"},{"key":"2025091917102978700_ref19","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1093\/humrep\/deab191","article-title":"Ageing and chronic disease-related changes in the morphometric characteristics of ovarian follicles in cynomolgus monkeys (Macaca fascicularis)","volume":"36","author":"Grin","year":"2021","journal-title":"Hum Reprod"},{"key":"2025091917102978700_ref20","first-page":"93","article-title":"Metastatic or embolic endometriosis, due to the menstrual dissemination of endometrial tissue into the venous circulation","volume":"3","author":"Sampson","year":"1927","journal-title":"Am J Pathol"},{"key":"2025091917102978700_ref21","first-page":"412","article-title":"Endometriosis and mullerian anomalies","volume":"69","author":"Olive","year":"1987","journal-title":"Obstet Gynecol"},{"key":"2025091917102978700_ref22","doi-asserted-by":"crossref","first-page":"52S","DOI":"10.1097\/00006250-198003001-00017","article-title":"Iatrogenic endometriosis: substantiation of the Sampson hypothesis","volume":"55","author":"Szlachter","year":"1980","journal-title":"Obstet Gynecol"},{"key":"2025091917102978700_ref23","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/molehr\/gap057","article-title":"The non-human primate model of endometriosis: research and implications for fecundity","volume":"15","author":"Braundmeier","year":"2009","journal-title":"Mol Hum Reprod"},{"key":"2025091917102978700_ref24","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0015-0282(16)56957-X","article-title":"Development of a model of retrograde menstruation in baboons (Papio anubis)","volume":"62","author":"D'Hooghe","year":"1994","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref25","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0002-9378(95)90180-9","article-title":"Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis)","volume":"173","author":"D'Hooghe","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"2025091917102978700_ref26","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0015-0282(16)58641-5","article-title":"The cycle pregnancy rate is normal in baboons with stage I endometriosis but decreased in primates with stage II and stage III-IV disease","volume":"66","author":"D'Hooghe","year":"1996","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref27","doi-asserted-by":"crossref","first-page":"e2300481","DOI":"10.1002\/smll.202300481","article-title":"Bioactive injectable and self-healing hydrogel via cell-free fat extract for endometrial regeneration","volume":"19","author":"Xu","year":"2023","journal-title":"Small"},{"key":"2025091917102978700_ref28","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/S0015-0282(16)47552-7","article-title":"Etiology of infertility in monkeys with endometriosis: luteinized unruptured follicles, luteal phase defects, pelvic adhesions, and spontaneous abortions","volume":"41","author":"Schenken","year":"1984","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref29","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1749-6632.2002.tb02791.x","article-title":"A modified baboon model for endometriosis","volume":"955","author":"Fazleabas","year":"2002","journal-title":"Ann N Y Acad Sci"},{"key":"2025091917102978700_ref30","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1186\/1477-7827-4-S1-S7","article-title":"A baboon model for endometriosis: implications for fertility","volume":"4 Suppl 1","author":"Hastings","year":"2006","journal-title":"Reprod Biol Endocrinol"},{"key":"2025091917102978700_ref31","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1095\/biolreprod.112.104497","article-title":"Changes in eutopic endometrial gene expression during the progression of experimental endometriosis in the baboon, Papio anubis","volume":"88","author":"Afshar","year":"2013","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref32","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1177\/1933719111401663","article-title":"Cofilin and slingshot localization in the epithelium of uterine endometrium changes during the menstrual cycle and in endometriosis","volume":"18","author":"Morris","year":"2011","journal-title":"Reprod Sci"},{"key":"2025091917102978700_ref33","doi-asserted-by":"crossref","first-page":"3068","DOI":"10.1093\/humrep\/del310","article-title":"Morphological and glycosylation changes associated with the endometrium and ectopic lesions in a baboon model of endometriosis","volume":"21","author":"Jones","year":"2006","journal-title":"Hum Reprod"},{"key":"2025091917102978700_ref34","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1177\/1933719106298409","article-title":"The altered distribution of the steroid hormone receptors and the chaperone immunophilin FKBP52 in a baboon model of endometriosis is associated with progesterone resistance during the window of uterine receptivity","volume":"14","author":"Jackson","year":"2007","journal-title":"Reprod Sci"},{"key":"2025091917102978700_ref35","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1530\/REP-15-0212","article-title":"Arginine methyltransferases mediate an epigenetic ovarian response to endometriosis","volume":"150","author":"Baumann","year":"2015","journal-title":"Reproduction"},{"key":"2025091917102978700_ref36","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1095\/biolreprod.108.072496","article-title":"Endometriosis is associated with progesterone resistance in the baboon (Papio anubis) oviduct: evidence based on the localization of oviductal glycoprotein 1 (OVGP1)","volume":"80","author":"Wang","year":"2009","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref37","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S0015-0282(16)54496-3","article-title":"Lack of effect of peritoneal endometriosis on fertility in the rabbit model","volume":"56","author":"Dunselman","year":"1991","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref38","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1210\/er.2018-00242","article-title":"Endometriosis","volume":"40","author":"Bulun","year":"2019","journal-title":"Endocr Rev"},{"key":"2025091917102978700_ref39","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0015-0282(00)00552-5","article-title":"Effect of peritoneal fluid from women with endometriosis on implantation in the mouse model","volume":"74","author":"Illera","year":"2000","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref40","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/S0015-0282(16)53533-X","article-title":"Peritoneal fluid from endometriosis patients affects reproductive outcome in an in vivo model","volume":"53","author":"Steinleitner","year":"1990","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref41","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s12929-022-00883-2","article-title":"Oleuropein suppresses endometriosis progression and improves the fertility of mice with endometriosis","volume":"29","author":"Park","year":"2022","journal-title":"J Biomed Sci"},{"key":"2025091917102978700_ref42","doi-asserted-by":"crossref","first-page":"e0121545","DOI":"10.1371\/journal.pone.0121545","article-title":"Compatibility of a novel thrombospondin-1 analog with fertility and pregnancy in a xenograft mouse model of endometriosis","volume":"10","author":"Nakamura","year":"2015","journal-title":"PLoS One"},{"key":"2025091917102978700_ref43","doi-asserted-by":"crossref","first-page":"5883","DOI":"10.1038\/s41598-017-06081-7","article-title":"A balancing act: RNA binding protein HuR\/TTP axis in endometriosis patients","volume":"7","author":"Khalaj","year":"2017","journal-title":"Sci Rep"},{"key":"2025091917102978700_ref44","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1007\/s43032-022-00980-5","article-title":"A mouse model of endometriosis with nanoparticle Labeling for in vivo photoacoustic imaging","volume":"29","author":"Marquardt","year":"2022","journal-title":"Reprod Sci"},{"key":"2025091917102978700_ref45","doi-asserted-by":"crossref","first-page":"1158527","DOI":"10.3389\/fendo.2023.1158527","article-title":"A novel therapeutic approach for endometriosis using adipose-derived stem cell-derived conditioned medium\u2014a new hope for endometriotic patients in improving fertility","volume":"14","author":"Huang","year":"2023","journal-title":"Front Endocrinol"},{"key":"2025091917102978700_ref46","article-title":"A syngeneic murine model of endometriosis using naturally cycling mice","volume":"24","author":"Richards","year":"2020","journal-title":"J Vis Exp"},{"key":"2025091917102978700_ref47","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1007\/s43032-023-01426-2","article-title":"Alteration in effects of endometriosis on fecundity according to pregnancy experience in mouse model","volume":"31","author":"Park","year":"2024","journal-title":"Reprod Sci"},{"key":"2025091917102978700_ref48","doi-asserted-by":"crossref","first-page":"e13307","DOI":"10.1111\/aji.13307","article-title":"Correlation of fecal metabolomics and gut microbiota in mice with endometriosis","volume":"84","author":"Ni","year":"2020","journal-title":"Am J Reprod Immunol"},{"key":"2025091917102978700_ref49","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1530\/JME-20-0193","article-title":"Decreased mixed lineage leukemia 1 is involved in endometriosis-related infertility","volume":"66","author":"Wen","year":"2021","journal-title":"J Mol Endocrinol"},{"key":"2025091917102978700_ref50","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s10815-014-0390-1","article-title":"Effect of induced peritoneal endometriosis on oocyte and embryo quality in a mouse model","volume":"32","author":"Cohen","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"2025091917102978700_ref51","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41420-023-01309-0","article-title":"Gut microbiota and microbiota-derived metabolites promotes endometriosis","volume":"9","author":"Chadchan","year":"2023","journal-title":"Cell Death Discovery"},{"key":"2025091917102978700_ref52","article-title":"Impact of chronic exposure to endometriosis on perinatal outcomes: establishment of a mouse model","volume":"10","author":"Elsherbini","year":"2022","journal-title":"Biomedicine"},{"key":"2025091917102978700_ref53","doi-asserted-by":"crossref","first-page":"e11948","DOI":"10.1590\/1414-431x2022e11948","article-title":"In vitro maturation medium supplementation: utilization of repaglinide, L-carnitine, and mesenchymal stem cell-conditioned medium to improve developmental competence of oocytes derived from endometriosis mouse models","volume":"55","author":"Kalehoei","year":"2022","journal-title":"Braz J Med Biol Res"},{"key":"2025091917102978700_ref54","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/s41419-022-05037-8","article-title":"Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity","volume":"13","author":"Ni","year":"2022","journal-title":"Cell Death Dis"},{"key":"2025091917102978700_ref55","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12958-023-01151-0","article-title":"METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility","volume":"21","author":"Li","year":"2023","journal-title":"Reprod Biol Endocrinol"},{"key":"2025091917102978700_ref56","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.7150\/ijbs.58657","article-title":"Protopanaxadiol improves endometriosis associated infertility and miscarriage in sex hormones receptors-dependent and independent manners","volume":"17","author":"Lai","year":"2021","journal-title":"Int J Biol Sci"},{"key":"2025091917102978700_ref57","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1111\/jog.15569","article-title":"Therapeutic effects of L-arginine, L-carnitine, and mesenchymal stem cell-conditioned medium on endometriosis-induced oocyte poor quality in an experimental mouse model","volume":"49","author":"Kalehoei","year":"2023","journal-title":"J Obstet Gynaecol Res"},{"key":"2025091917102978700_ref58","first-page":"65","article-title":"Uterine administration of C-X-C motif chemokine ligand 12 increases the pregnancy rates in mice with induced endometriosis","volume":"4","author":"ACJS","year":"2023","journal-title":"F S Sci"},{"key":"2025091917102978700_ref59","doi-asserted-by":"crossref","DOI":"10.1002\/jcp.31188","article-title":"Vaginal extracellular vesicles impair fertility in endometriosis by favoring Th17\/Treg imbalance and inhibiting sperm activity","volume":"239","author":"Zhang","year":"2024","journal-title":"J Cell Physiol"},{"key":"2025091917102978700_ref60","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3181\/00379727-212-44022","article-title":"Effect of surgically induced endometriosis on pregnancy and effect of pregnancy and lactation on endometriosis in mice","volume":"212","author":"Cummings","year":"1996","journal-title":"Proc Soc Exp Biol Med"},{"key":"2025091917102978700_ref61","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/path.4922","article-title":"Targeting hypoxia-mediated YAP1 nuclear translocation ameliorates pathogenesis of endometriosis without compromising maternal fertility","volume":"242","author":"Lin","year":"2017","journal-title":"J Pathol"},{"key":"2025091917102978700_ref62","doi-asserted-by":"crossref","DOI":"10.1016\/j.rbmo.2024.104474","article-title":"Metformin reverses infertility in a mouse model of endometriosis: unveiling disease pathways and implications for future clinical approaches","volume":"50","author":"Neto","year":"2025","journal-title":"Reprod Biomed Online"},{"key":"2025091917102978700_ref63","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/S0015-0282(16)54674-3","article-title":"Immunomodulation in the treatment of endometriosis-associated subfertility: use of pentoxifylline to reverse the inhibition of fertilization by surgically induced endometriosis in a rodent model","volume":"56","author":"Steinleitner","year":"1991","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref64","first-page":"949","article-title":"Periovulatory calcium channel blockade enhances reproductive performance in an animal model for endometriosis-associated subfertility","volume":"164","author":"Steinleitner","year":"1991","journal-title":"Am J Obstet Gynecol"},{"key":"2025091917102978700_ref65","first-page":"457","article-title":"Changes in natural killer (NK) activity and fertility during the establishment of experimental endometriosis in the rat","volume":"47","author":"Ishikawa","year":"1995","journal-title":"Nihon Sanka Fujinka Gakkai Zasshi"},{"key":"2025091917102978700_ref66","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2022.153951","article-title":"Effects of metformin, letrozole and atorvastatin on inflammation and apoptosis in experimental peritoneal and ovarian endometriosis in the rat","volume":"235","author":"Sapmaz","year":"2022","journal-title":"Pathol Res Pract"},{"key":"2025091917102978700_ref67","doi-asserted-by":"crossref","first-page":"e201900405","DOI":"10.1590\/s0102-865020190040000005","article-title":"Effects of omega-6\/3 and omega-9\/6 nutraceuticals on pain and fertility in peritoneal endometriosis in rats","volume":"34","author":"Pereira","year":"2019","journal-title":"Acta Cir Bras"},{"key":"2025091917102978700_ref68","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/S0015-0282(16)55572-1","article-title":"Experimentally induced endometriosis in rats: effect on fertility and the effects of pregnancy and lactation on the ectopic endometrial tissue","volume":"58","author":"Barrag\u00e1n","year":"1992","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref69","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.jep.2009.10.021","article-title":"Fertility inducing effect of aerial parts of Coccinia cordifolia L. in female rats","volume":"127","author":"Jha","year":"2010","journal-title":"J Ethnopharmacol"},{"key":"2025091917102978700_ref70","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/978-3-030-51856-1_2","article-title":"Identifying mechanisms of endometriosis-associated reduced fecundity in a rat model: novel insights toward understanding human infertility","volume":"232","author":"Sharpe-Timms","year":"2020","journal-title":"Adv Anat Embryol Cell Biol"},{"key":"2025091917102978700_ref71","doi-asserted-by":"crossref","first-page":"750208","DOI":"10.3389\/fphar.2022.750208","article-title":"Metformin alleviates endometriosis and potentiates endometrial receptivity via decreasing VEGF and MMP9 and increasing Leukemia inhibitor factor and HOXA10","volume":"13","author":"Cheng","year":"2022","journal-title":"Front Pharmacol"},{"key":"2025091917102978700_ref72","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1095\/biolreprod.108.073411","article-title":"Reduced fecundity in female rats with surgically induced endometriosis and in their daughters: a potential role for tissue inhibitors of metalloproteinase 1","volume":"80","author":"Stilley","year":"2009","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref73","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/S0015-0282(16)48988-0","article-title":"Studies on the surgical induction of endometriosis in the rat","volume":"44","author":"Vernon","year":"1985","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref74","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/jcmm.12427","article-title":"Telocytes damage in endometriosis-affected rat oviduct and potential impact on fertility","volume":"19","author":"Yang","year":"2015","journal-title":"J Cell Mol Med"},{"key":"2025091917102978700_ref75","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.25122\/jml-2021-0391","article-title":"The effect of endometriosis on fertility in an animal model","volume":"15","author":"Kanellopoulos","year":"2022","journal-title":"J Med Life"},{"key":"2025091917102978700_ref76","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/S0015-0282(16)49841-9","article-title":"The effect of treatment on experimentally produced endometrial peritoneal implants","volume":"46","author":"Golan","year":"1986","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref77","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1080\/09513590.2016.1190816","article-title":"The role and significance of endomorphin-1 and \u03bc-opioid receptor in rats with endometriosis","volume":"32","author":"Duan","year":"2016","journal-title":"Gynecol Endocrinol"},{"key":"2025091917102978700_ref78","article-title":"UPLC-Q-TOF\/MS based plasma metabolomics for identification of Paeonol's metabolic target in endometriosis","volume":"28","author":"Liu","year":"2023","journal-title":"Molecules"},{"key":"2025091917102978700_ref79","article-title":"Peritoneal endometriosis impairs ovarian reserve and increases atresia in a rat model","volume":"13","author":"Ricci","year":"2025","journal-title":"Biomedicine"},{"key":"2025091917102978700_ref80","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/humrep\/deae247","article-title":"Upregulated let-7 expression in the follicular fluid of patients with endometriomas leads to dysfunction of granulosa cells through targeting of IGF1R","volume":"40","author":"Shi","year":"2025","journal-title":"Hum Reprod"},{"key":"2025091917102978700_ref81","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1159\/000293611","article-title":"A rabbit model of endometriosis","volume":"27","author":"Dunselman","year":"1989","journal-title":"Gynecol Obstet Invest"},{"key":"2025091917102978700_ref82","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1093\/oxfordjournals.humrep.a136727","article-title":"Effect of endometriosis on early embryonic development in the rabbit","volume":"3","author":"Dunselman","year":"1988","journal-title":"Hum Reprod"},{"key":"2025091917102978700_ref83","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/0002-9378(86)90360-1","article-title":"Experimental evidence for failure to implant as a mechanism of infertility associated with endometriosis","volume":"155","author":"Hahn","year":"1986","journal-title":"Am J Obstet Gynecol"},{"key":"2025091917102978700_ref84","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1055\/s-0037-1601484","article-title":"The effect of mesenchymal stem cells on fertility in experimental Retrocervical endometriosis","volume":"39","author":"Abreu","year":"2017","journal-title":"Rev Bras Ginecol Obstet"},{"key":"2025091917102978700_ref85","first-page":"282","article-title":"The effect of a luteinizing hormone releasing hormone (LRH) agonist (Wy-40,972), levonorgestrel, danazol and ovariectomy on experimental endometriosis in the rat","volume":"106","author":"Jones","year":"1984","journal-title":"Acta Endocrinol"},{"key":"2025091917102978700_ref86","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0304-3940(01)01906-1","article-title":"Vaginal hyperalgesia in a rat model of endometriosis","volume":"306","author":"Berkley","year":"2001","journal-title":"Neurosci Lett"},{"key":"2025091917102978700_ref87","doi-asserted-by":"crossref","first-page":"S150","DOI":"10.1016\/j.pain.2007.09.022","article-title":"Endometriosis-induced vaginal hyperalgesia in the rat: effect of estropause, ovariectomy, and estradiol replacement","volume":"132 Suppl 1","author":"Berkley","year":"2007","journal-title":"Pain"},{"key":"2025091917102978700_ref88","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.pain.2009.09.022","article-title":"Endometriosis-induced vaginal hyperalgesia in the rat: role of the ectopic growths and their innervation","volume":"147","author":"McAllister","year":"2009","journal-title":"Pain"},{"key":"2025091917102978700_ref89","doi-asserted-by":"crossref","DOI":"10.1093\/database\/baz062","article-title":"Endometriosis Knowledgebase: a gene-based resource on endometriosis","volume":"2019","author":"Joseph","year":"2019","journal-title":"Database (Oxford)"},{"key":"2025091917102978700_ref90","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/s41467-022-28608-x","article-title":"Loss of MIG-6 results in endometrial progesterone resistance via ERBB2","volume":"13","author":"Yoo","year":"2022","journal-title":"Nat Commun"},{"key":"2025091917102978700_ref91","first-page":"182","article-title":"Transcriptomic changes in eutopic endometrium and ectopic lesions during endometriosis progression in a mouse model","volume":"5","author":"Li","year":"2024","journal-title":"F S Sci"},{"key":"2025091917102978700_ref92","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1093\/humrep\/dez253","article-title":"A mouse model of endometriosis mimicking the natural spread of invasive endometrium","volume":"35","author":"Wilson","year":"2020","journal-title":"Hum Reprod"},{"key":"2025091917102978700_ref93","article-title":"Establishment of an experimental mouse model of endometrioma to study its related infertility","volume":"206","author":"Tan","year":"2024","journal-title":"J Vis Exp"},{"key":"2025091917102978700_ref94","doi-asserted-by":"crossref","first-page":"101726","DOI":"10.1016\/j.redox.2020.101726","article-title":"Novel ovarian endometriosis model causes infertility via iron-mediated oxidative stress in mice","volume":"37","author":"Hayashi","year":"2020","journal-title":"Redox Biol"},{"key":"2025091917102978700_ref95","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.049070","article-title":"Bioluminescent imaging in induced mouse models of endometriosis reveals differences in four model variations","volume":"14","author":"Dorning","year":"2021","journal-title":"Dis Model Mech"},{"key":"2025091917102978700_ref96","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.2353\/ajpath.2006.051133","article-title":"A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy","volume":"168","author":"Becker","year":"2006","journal-title":"Am J Pathol"},{"key":"2025091917102978700_ref97","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1210\/clinem\/dgab753","article-title":"Role of SIRT1 and progesterone resistance in normal and abnormal endometrium","volume":"107","author":"Kim","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"key":"2025091917102978700_ref98","article-title":"Noninvasive monitoring of lesion size in a heterologous mouse model of endometriosis","volume":"144","author":"Martinez","year":"2019","journal-title":"J Vis Exp"},{"key":"2025091917102978700_ref99","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1095\/biolreprod.116.140756","article-title":"A novel homologous model for noninvasive monitoring of endometriosis progression","volume":"96","author":"Ferrero","year":"2017","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref100","doi-asserted-by":"crossref","first-page":"e1005537","DOI":"10.1371\/journal.pgen.1005537","article-title":"ARID1A is essential for endometrial function during early pregnancy","volume":"11","author":"Kim","year":"2015","journal-title":"PLoS Genet"},{"key":"2025091917102978700_ref101","doi-asserted-by":"crossref","first-page":"e21209","DOI":"10.1096\/fj.202002178R","article-title":"Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment","volume":"35","author":"Marquardt","year":"2021","journal-title":"FASEB J"},{"key":"2025091917102978700_ref102","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23116067","article-title":"Endometrial epithelial ARID1A is required for uterine immune homeostasis during early pregnancy","volume":"23","author":"Marquardt","year":"2022","journal-title":"Int J Mol Sci"},{"key":"2025091917102978700_ref103","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1093\/humupd\/dmv035","article-title":"The impact of endometrioma on IVF\/ICSI outcomes: a systematic review and meta-analysis","volume":"21","author":"Hamdan","year":"2015","journal-title":"Hum Reprod Update"},{"key":"2025091917102978700_ref104","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1007\/s43032-020-00164-z","article-title":"Endometriosis: the role of iron overload and Ferroptosis","volume":"27","author":"Ng","year":"2020","journal-title":"Reprod Sci"},{"key":"2025091917102978700_ref105","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1093\/humupd\/dmab035","article-title":"The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain","volume":"28","author":"Salliss","year":"2021","journal-title":"Hum Reprod Update"},{"key":"2025091917102978700_ref106","doi-asserted-by":"crossref","first-page":"40.e1","DOI":"10.1016\/j.ajog.2016.07.041","article-title":"First evidence of a menstruating rodent: the spiny mouse (Acomys cahirinus)","volume":"216","author":"Bellofiore","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"2025091917102978700_ref107","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1071\/RD18506","article-title":"Pseudopregnancy and reproductive cycle synchronisation cannot be induced using conventional methods in the spiny mouse (Acomys cahirinus)","volume":"32","author":"Bellofiore","year":"2020","journal-title":"Reprod Fertil Dev"},{"key":"2025091917102978700_ref108","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1530\/JME-17-0278","article-title":"A missing piece: the spiny mouse and the puzzle of menstruating species","volume":"61","author":"Bellofiore","year":"2018","journal-title":"J Mol Endocrinol"},{"key":"2025091917102978700_ref109","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1210\/endrev\/bnad020","article-title":"Epigenetic dysregulation in endometriosis: implications for pathophysiology and therapeutics","volume":"44","author":"Marquardt","year":"2023","journal-title":"Endocr Rev"},{"key":"2025091917102978700_ref110","doi-asserted-by":"crossref","first-page":"1223828","DOI":"10.3389\/fimmu.2023.1223828","article-title":"The landscape of non-coding RNAs in the immunopathogenesis of endometriosis","volume":"14","author":"Abbaszadeh","year":"2023","journal-title":"Front Immunol"},{"key":"2025091917102978700_ref111","doi-asserted-by":"crossref","first-page":"3814","DOI":"10.1210\/en.2006-1692","article-title":"Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis","volume":"148","author":"Burney","year":"2007","journal-title":"Endocrinology"},{"key":"2025091917102978700_ref112","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1210\/en.2009-0923","article-title":"The protein kinase a pathway-regulated transcriptome of endometrial stromal fibroblasts reveals compromised differentiation and persistent proliferative potential in endometriosis","volume":"151","author":"Aghajanova","year":"2010","journal-title":"Endocrinology"},{"key":"2025091917102978700_ref113","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1111\/cas.14871","article-title":"Biological significance of KRAS mutant allele expression in ovarian endometriosis","volume":"112","author":"Yachida","year":"2021","journal-title":"Cancer Sci"},{"key":"2025091917102978700_ref114","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.bbrc.2009.05.115","article-title":"HIC1 interacts with a specific subunit of SWI\/SNF complexes, ARID1A\/BAF250A","volume":"385","author":"Van Rechem","year":"2009","journal-title":"Biochem Biophys Res Commun"},{"key":"2025091917102978700_ref115","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1056\/NEJMoa1614814","article-title":"Cancer-associated mutations in endometriosis without cancer","volume":"376","author":"Anglesio","year":"2017","journal-title":"N Engl J Med"},{"key":"2025091917102978700_ref116","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.celrep.2018.07.037","article-title":"Clonal expansion and diversification of cancer-associated mutations in endometriosis and normal endometrium","volume":"24","author":"Suda","year":"2018","journal-title":"Cell Rep"},{"key":"2025091917102978700_ref117","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1002\/cjp2.317","article-title":"KRAS mutations and endometriosis burden of disease","volume":"9","author":"Orr","year":"2023","journal-title":"J Pathol Clin Res"},{"key":"2025091917102978700_ref118","doi-asserted-by":"crossref","first-page":"6765","DOI":"10.1038\/s41598-017-04577-w","article-title":"KRAS activation and over-expression of SIRT1\/BCL6 contributes to the pathogenesis of endometriosis and progesterone resistance","volume":"7","author":"Yoo","year":"2017","journal-title":"Sci Rep"},{"key":"2025091917102978700_ref119","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1093\/biolre\/ioac026","article-title":"SIRT1 plays an important role in implantation and decidualization during mouse early pregnancy","volume":"106","author":"Hwang","year":"2022","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref120","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.rbmo.2015.04.005","article-title":"Expression of KRAS in the endometrium of early pregnant mice and its effect during embryo implantation","volume":"31","author":"Long","year":"2015","journal-title":"Reprod Biomed Online"},{"key":"2025091917102978700_ref121","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1128\/MCB.25.1.324-335.2005","article-title":"Reading and function of a histone code involved in targeting corepressor complexes for repression","volume":"25","author":"Yoon","year":"2005","journal-title":"Mol Cell Biol"},{"key":"2025091917102978700_ref122","doi-asserted-by":"crossref","first-page":"2956","DOI":"10.1093\/humrep\/dem241","article-title":"Class I histone deacetylase expression in the human cyclic endometrium and endometrial adenocarcinomas","volume":"22","author":"Krusche","year":"2007","journal-title":"Hum Reprod"},{"key":"2025091917102978700_ref123","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s00404-012-2591-0","article-title":"Aberrant histone acetylation and methylation levels in woman with endometriosis","volume":"287","author":"Xiaomeng","year":"2013","journal-title":"Arch Gynecol Obstet"},{"key":"2025091917102978700_ref124","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1177\/1933719111432870","article-title":"HDAC1 and HDAC2 are differentially expressed in endometriosis","volume":"19","author":"Col\u00f3n-D\u00edaz","year":"2012","journal-title":"Reprod Sci"},{"volume-title":"Role of HDAC3 in the pathophysiology of endometriosis","author":"Estrada","key":"2025091917102978700_ref125"},{"key":"2025091917102978700_ref126","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1177\/1933719113497267","article-title":"Endometriosis is characterized by a distinct pattern of histone 3 and histone 4 lysine modifications","volume":"21","author":"Monteiro","year":"2014","journal-title":"Reprod Sci"},{"key":"2025091917102978700_ref127","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaf7533","article-title":"Loss of HDAC3 results in nonreceptive endometrium and female infertility","volume":"11","author":"Kim","year":"2019","journal-title":"Sci Transl Med"},{"key":"2025091917102978700_ref128","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/s13578-020-00505-0","article-title":"Post-translational modifications of EZH2 in cancer","volume":"10","author":"Li","year":"2020","journal-title":"Cell Biosci"},{"key":"2025091917102978700_ref129","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqac210","article-title":"Decreased expression of EZH2 in granulosa cells contributes to endometriosis-associated infertility by targeting IL-1R2","volume":"164","author":"Lin","year":"2022","journal-title":"Endocrinology"},{"key":"2025091917102978700_ref130","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1002\/kjm2.12626","article-title":"METTL3 is aberrantly expressed in endometriosis and suppresses proliferation, invasion, and migration of endometrial stromal cells","volume":"39","author":"Zhang","year":"2023","journal-title":"Kaohsiung J Med Sci"},{"key":"2025091917102978700_ref131","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1093\/biolre\/ioab152","article-title":"Inhibition of METTL3\/m6A\/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis\u2020","volume":"105","author":"Li","year":"2021","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref132","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.rbmo.2022.10.010","article-title":"METTL3 and METTL14-mediated N6-methyladenosine modification promotes cell proliferation and invasion in a model of endometriosis","volume":"46","author":"Shen","year":"2023","journal-title":"Reprod Biomed Online"},{"key":"2025091917102978700_ref133","doi-asserted-by":"crossref","DOI":"10.1002\/jcp.31367","article-title":"m6A methylation of RNF43 inhibits the progression of endometriosis through regulating oxidative phosphorylation via NDUFS1","volume":"239","author":"Tang","year":"2024","journal-title":"J Cell Physiol"},{"key":"2025091917102978700_ref134","doi-asserted-by":"crossref","first-page":"421","DOI":"10.31083\/j.fbl2912421","article-title":"Downregulated METTL3 accumulates TERT expression that promote the progression of ovarian endometriosis","volume":"29","author":"Li","year":"2024","journal-title":"Front Biosci"},{"key":"2025091917102978700_ref135","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1186\/s12967-023-04209-0","article-title":"METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing","volume":"21","author":"Wang","year":"2023","journal-title":"J Transl Med"},{"key":"2025091917102978700_ref136","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1530\/REP-22-0102","article-title":"m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG","volume":"165","author":"Li","year":"2023","journal-title":"Reproduction"},{"key":"2025091917102978700_ref137","doi-asserted-by":"crossref","DOI":"10.1530\/REP-23-0336","article-title":"METTL3-dependent m6A modification facilitates decreased endometrial decidualization via attenuation of MET in endometriosis","volume":"168","author":"Xiong","year":"2024","journal-title":"Reproduction"},{"key":"2025091917102978700_ref138","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41419-023-05866-1","article-title":"METTL3-dependent m6A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling","volume":"14","author":"Wan","year":"2023","journal-title":"Cell Death Dis"},{"key":"2025091917102978700_ref139","doi-asserted-by":"crossref","first-page":"e2214684120","DOI":"10.1073\/pnas.2214684120","article-title":"METTL3 is essential for normal progesterone signaling during embryo implantation via m6A-mediated translation control of progesterone receptor","volume":"120","author":"Zheng","year":"2023","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2025091917102978700_ref140","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1177\/1933719119828078","article-title":"Progesterone receptor B (PGR-B) is partially methylated in Eutopic endometrium from infertile women with endometriosis","volume":"26","author":"Rocha-Junior","year":"2019","journal-title":"Reprod Sci"},{"key":"2025091917102978700_ref141","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.tem.2018.05.006","article-title":"Progesterone resistance in endometriosis: an acquired property?","volume":"29","author":"McKinnon","year":"2018","journal-title":"Trends Endocrinol Metab"},{"key":"2025091917102978700_ref142","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1093\/humupd\/dmz012","article-title":"Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis","volume":"25","author":"Horton","year":"2019","journal-title":"Hum Reprod Update"},{"key":"2025091917102978700_ref143","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1186\/s12916-022-02500-3","article-title":"Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis","volume":"20","author":"Shih","year":"2022","journal-title":"BMC Med"},{"key":"2025091917102978700_ref144","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.reprotox.2016.07.007","article-title":"Exposure to the environmental endocrine disruptor TCDD and human reproductive dysfunction: translating lessons from murine models","volume":"68","author":"Bruner-Tran","year":"2017","journal-title":"Reprod Toxicol"},{"key":"2025091917102978700_ref145","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/nm1173","article-title":"Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer","volume":"11","author":"Dinulescu","year":"2005","journal-title":"Nat Med"},{"key":"2025091917102978700_ref146","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/biolre\/ioy030","article-title":"Effects of histone methyltransferase inhibition in endometriosis","volume":"99","author":"Col\u00f3n-Caraballo","year":"2018","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref147","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1177\/1933719117718275","article-title":"Histological and Immunohistochemical characterization of the similarity and difference between ovarian Endometriomas and deep infiltrating endometriosis","volume":"25","author":"Liu","year":"2018","journal-title":"Reprod Sci"},{"key":"2025091917102978700_ref148","doi-asserted-by":"crossref","first-page":"6804","DOI":"10.1038\/s41598-017-06920-7","article-title":"Enhancer of Zeste homolog 2 (EZH2) induces epithelial-mesenchymal transition in endometriosis","volume":"7","author":"Zhang","year":"2017","journal-title":"Sci Rep"},{"key":"2025091917102978700_ref149","doi-asserted-by":"crossref","first-page":"e1009483","DOI":"10.1371\/journal.pgen.1009483","article-title":"Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics","volume":"17","author":"Roy","year":"2021","journal-title":"PLoS Genet"},{"key":"2025091917102978700_ref150","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1210\/en.2017-00145","article-title":"Androgens regulate ovarian gene expression through modulation of Ezh2 expression and activity","volume":"158","author":"Ma","year":"2017","journal-title":"Endocrinology"},{"key":"2025091917102978700_ref151","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/s41586-019-1534-3","article-title":"The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape","volume":"573","author":"Weinberg","year":"2019","journal-title":"Nature"},{"key":"2025091917102978700_ref152","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jri.2004.12.002","article-title":"Constitutive or induced elevated levels of L-carnitine correlate with the cytokine and cellular profile of endometriosis","volume":"65","author":"Dionyssopoulou","year":"2005","journal-title":"J Reprod Immunol"},{"key":"2025091917102978700_ref153","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.fertnstert.2008.02.097","article-title":"L-carnitine supplementation reduces oocyte cytoskeleton damage and embryo apoptosis induced by incubation in peritoneal fluid from patients with endometriosis","volume":"91","author":"Mansour","year":"2009","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref154","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1006\/faat.1993.1119","article-title":"Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin","volume":"21","author":"Rier","year":"1993","journal-title":"Fundam Appl Toxicol"},{"key":"2025091917102978700_ref155","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.bbrc.2022.05.092","article-title":"Evaluation of the potential role of diethylstilbestrol on the induction of endometriosis in a rat model - an alternative approach","volume":"617","author":"Krishnamoorthy","year":"2022","journal-title":"Biochem Biophys Res Commun"},{"key":"2025091917102978700_ref156","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s12940-021-00780-5","article-title":"Multigenerational endometriosis: consequence of fetal exposure to diethylstilbestrol ?","volume":"20","author":"Gaspari","year":"2021","journal-title":"Environ Health"},{"key":"2025091917102978700_ref157","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0015-0282(99)00153-3","article-title":"Effect of diethylstilbestrol on reproductive function","volume":"72","author":"Goldberg","year":"1999","journal-title":"Fertil Steril"},{"key":"2025091917102978700_ref158","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1093\/biolre\/ioab153","article-title":"Evidence of intergenerational transmission of diethylstilbestrol health effects: hindsight and insight","volume":"105","author":"Titus","year":"2021","journal-title":"Biol Reprod"},{"key":"2025091917102978700_ref159","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00404-009-1191-0","article-title":"The pathophysiology of endometriosis and adenomyosis: tissue injury and repair","volume":"280","author":"Leyendecker","year":"2009","journal-title":"Arch Gynecol Obstet"},{"key":"2025091917102978700_ref160","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1196\/annals.1335.036","article-title":"Uterine peristaltic activity and the development of endometriosis","volume":"1034","author":"Leyendecker","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"2025091917102978700_ref161","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1111\/aogs.13428","article-title":"Comparison of dienogest and progesterone effects on uterine contractility in the extracorporeal perfusion model of swine uteri","volume":"97","author":"Oppelt","year":"2018","journal-title":"Acta Obstet Gynecol Scand"},{"key":"2025091917102978700_ref162","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.rbmo.2022.03.016","article-title":"Endometriosis organoids: prospects and challenges","volume":"45","author":"Esfandiari","year":"2022","journal-title":"Reprod Biomed Online"},{"key":"2025091917102978700_ref163","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1038\/s41556-019-0360-z","article-title":"Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening","volume":"21","author":"Boretto","year":"2019","journal-title":"Nat Cell Biol"},{"key":"2025091917102978700_ref164","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.160815","article-title":"Spheroids as a model for endometriotic lesions","volume":"8","author":"Song","year":"2023","journal-title":"JCI Insight"},{"key":"2025091917102978700_ref165","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/pd.800","article-title":"The artificial uterus","volume":"24","author":"Adinolfi","year":"2004","journal-title":"Prenat Diagn"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/biolreprod\/advance-article-pdf\/doi\/10.1093\/biolre\/ioaf089\/62925522\/ioaf089.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-pdf\/113\/3\/494\/62925522\/ioaf089.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-pdf\/113\/3\/494\/62925522\/ioaf089.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T21:10:50Z","timestamp":1758316250000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article\/113\/3\/494\/8113203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,14]]},"references-count":165,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,4,14]]},"published-print":{"date-parts":[[2025,9,15]]}},"URL":"https:\/\/doi.org\/10.1093\/biolre\/ioaf089","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"type":"print","value":"0006-3363"},{"type":"electronic","value":"1529-7268"}],"subject":[],"published-other":{"date-parts":[[2025,9]]},"published":{"date-parts":[[2025,4,14]]}}}