{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:31:06Z","timestamp":1783488666181,"version":"3.55.0"},"reference-count":153,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T00:00:00Z","timestamp":1498176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","award":["31003A_160251"],"award-info":[{"award-number":["31003A_160251"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the dog, there is no luteolysis in the absence of pregnancy. Thus, this species lacks any anti-luteolytic endocrine signal as found in other species that modulate uterine function during the critical period of pregnancy establishment. Nevertheless, in the dog an embryo-maternal communication must occur in order to prevent rejection of embryos. Based on this hypothesis, we performed microarray analysis of canine uterine samples collected during pre-attachment phase (days 10-12) and in corresponding non-pregnant controls, in order to elucidate the embryo attachment signal. An additional goal was to identify differences in uterine responses to pre-attachment embryos between dogs and other mammalian species exhibiting different reproductive patterns with regard to luteolysis, implantation, and preparation for placentation. Therefore, the canine microarray data were compared with gene sets from pigs, cattle, horses, and humans. We found 412 genes differentially regulated between the two experimental groups. The functional terms most strongly enriched in response to pre-attachment embryos related to extracellular matrix function and remodeling, and to immune and inflammatory responses. Several candidate genes were validated by semi-quantitative PCR. When compared with other species, best matches were found with human and equine counterparts. Especially for the pig, the majority of overlapping genes showed opposite expression patterns. Interestingly, 1926 genes did not pair with any of the other gene sets. Using a microarray approach, we report the uterine changes in the dog driven by the presence of embryos and compare these results with datasets from other mammalian species, finding common-, contrary-, and exclusively canine-regulated genes.<\/jats:p>","DOI":"10.1093\/biolre\/iox063","type":"journal-article","created":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T06:47:05Z","timestamp":1498200425000},"page":"197-216","source":"Crossref","is-referenced-by-count":31,"title":["Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species\u2020"],"prefix":"10.1093","volume":"97","author":[{"given":"Felix R","family":"Graubner","sequence":"first","affiliation":[{"name":"Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aykut","family":"Gram","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Kautz","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Bauersachs","sequence":"additional","affiliation":[{"name":"Institute of Agricultural Sciences, Animal Physiology, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selim","family":"Aslan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Near East University, Nicosia, North Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali R","family":"Agaoglu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, Burdur, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alois","family":"Boos","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz P","family":"Kowalewski","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,6,23]]},"reference":[{"key":"2019070503124678100_bib1","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1126\/science.1071601","article-title":"Deciphering the cross-talk of implantation: advances and challenges","volume":"296","author":"Paria","year":"2002","journal-title":"Science"},{"key":"2019070503124678100_bib2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/978-3-319-15856-3_2","article-title":"History of maternal recognition of pregnancy","volume":"216","author":"Bazer","year":"2015","journal-title":"Adv Anat Embryol Cell Biol"},{"key":"2019070503124678100_bib3","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/molehr\/gap095","article-title":"Novel pathways for implantation and establishment and maintenance of pregnancy in mammals","volume":"16","author":"Bazer","year":"2010","journal-title":"Mol Hum Reprod"},{"key":"2019070503124678100_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.2000.80.1.1","article-title":"Mechanisms controlling the function and life span of the corpus luteum","volume":"80","author":"Niswender","year":"2000","journal-title":"Physiol Rev"},{"key":"2019070503124678100_bib5","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/9780470719688.ch2","article-title":"Implantation and the maternal recognition of pregnancy","volume-title":"Ciba Foundation Symposium - Foetal Autonomy","author":"Short","year":"1969"},{"key":"2019070503124678100_bib6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/245045a0","article-title":"Steroid hormone production by pig blastocysts","volume":"245","author":"Perry","year":"1973","journal-title":"Nature"},{"key":"2019070503124678100_bib7","first-page":"39","article-title":"Physiological mechanisms of pregnancy recognition in ruminants","volume":"43","author":"Bazer","year":"1991","journal-title":"J Reprod Fertil Suppl"},{"key":"2019070503124678100_bib8","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1477-7827-2-49","article-title":"Conceptus signals for establishment and maintenance of pregnancy","volume":"2","author":"Spencer","year":"2004","journal-title":"Reprod Biol Endocrinol"},{"key":"2019070503124678100_bib9","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0143-4004(81)80021-5","article-title":"Conceptus attachment in the ewe: an ultrastructural study","volume":"2","author":"Guillomot","year":"1981","journal-title":"Placenta"},{"key":"2019070503124678100_bib10","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1530\/jrf.0.0190051","article-title":"A histological and histochemical examination of implantation and early placentome formation in sheep","volume":"19","author":"Boshier","year":"1969","journal-title":"J Reprod Fertil"},{"key":"2019070503124678100_bib11","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/ar.1092040404","article-title":"Ultrastructural features of the cell surfaces of uterine and trophoblastic epithelia during embryo attachment in the cow","volume":"204","author":"Guillomot","year":"1982","journal-title":"Anat Rec"},{"key":"2019070503124678100_bib12","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/ar.1091770403","article-title":"The origin of equine endometrial cups. II. Invasion of the endometrium by trophoblast","volume":"177","author":"Allen","year":"1973","journal-title":"Anat Rec"},{"key":"2019070503124678100_bib13","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1530\/jrf.0.0960837","article-title":"Ovarian and pituitary function in dogs after hysterectomy","volume":"96","author":"Hoffmann","year":"1992","journal-title":"J Reprod Fertil"},{"key":"2019070503124678100_bib14","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.theriogenology.2006.01.039","article-title":"Expression of cyclooxygenase 1 and 2 in the canine corpus luteum during diestrus","volume":"66","author":"Kowalewski","year":"2006","journal-title":"Theriogenology"},{"key":"2019070503124678100_bib15","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.anireprosci.2008.12.011","article-title":"Time related changes in luteal prostaglandin synthesis and steroidogenic capacity during pregnancy, normal and antiprogestin induced luteolysis in the bitch","volume":"116","author":"Kowalewski","year":"2009","journal-title":"Anim Reprod Sci"},{"key":"2019070503124678100_bib16","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1095\/biolreprod.113.109918","article-title":"Biosynthesis and degradation of canine placental prostaglandins: prepartum changes in expression and function of prostaglandin F2alpha-synthase (PGFS, AKR1C3) and 15-hydroxyprostaglandin dehydrogenase (HPGD)","volume":"89","author":"Gram","year":"2013","journal-title":"Biol Reprod"},{"key":"2019070503124678100_bib17","first-page":"3","article-title":"Biology and endocrinology of ovulation, pregnancy and parturition in the dog","volume":"39","author":"Concannon","year":"1989","journal-title":"J Reprod Fertil Suppl"},{"key":"2019070503124678100_bib18","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.anireprosci.2010.08.028","article-title":"Reproductive cycles of the domestic bitch","volume":"124","author":"Concannon","year":"2011","journal-title":"Anim Reprod Sci"},{"key":"2019070503124678100_bib19","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1055\/s-0029-1211280","article-title":"Investigations on hormonal changes around parturition in the dog and the occurrence of pregnancy-specific non conjugated oestrogens","volume":"102","author":"Hoffmann","year":"1994","journal-title":"Exp Clin Endocrinol"},{"key":"2019070503124678100_bib20","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1016\/S0093-691X(02)00644-1","article-title":"Comparisons of estradiol, LH and FSH patterns in pregnant and non-pregnant beagle bitches","volume":"57","author":"Onclin","year":"2002","journal-title":"Theriogenology"},{"key":"2019070503124678100_bib21","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1530\/jrf.0.0550181","article-title":"Hormonal and physical changes associated with bovine conceptus development","volume":"55","author":"Eley","year":"1979","journal-title":"J Reprod Fertil"},{"key":"2019070503124678100_bib22","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1530\/jrf.0.0550463","article-title":"Conjugated and unconjugated oestrogens in fetal and maternal fluids of the cow throughout pregnancy","volume":"55","author":"Robertson","year":"1979","journal-title":"J Reprod Fertil"},{"key":"2019070503124678100_bib23","first-page":"389","article-title":"Dehydroepiandrosterone synthesis by the fetal foal and its importance as an oestrogen precursor","volume":"32","author":"Pashen","year":"1982","journal-title":"J Reprod Fertil Suppl"},{"key":"2019070503124678100_bib24","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1530\/REP-13-0648","article-title":"Expression of genes involved in the embryo-maternal interaction in the early-pregnant canine uterus","volume":"147","author":"Kautz","year":"2014","journal-title":"Reproduction"},{"issue":"Suppl 2","key":"2019070503124678100_bib25","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/rda.12849","article-title":"Decidualization of the canine uterus: From early until late gestational in vivo morphological observations, and functional characterization of immortalized canine uterine stromal cell lines","volume":"52","author":"Graubner","year":"2017","journal-title":"Reprod Domest Anim"},{"key":"2019070503124678100_bib26","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/978-3-319-15856-3_11","article-title":"The dog: nonconformist, not only in maternal recognition signaling","volume":"216","author":"Kowalewski","year":"2015","journal-title":"Adv Anat Embryol Cell Biol"},{"key":"2019070503124678100_bib27","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/1097-0185(20000901)260:1<42::AID-AR50>3.0.CO;2-8","article-title":"Immunohistochemical detection of the estrogen receptor-alpha and progesterone receptor in the canine pregnant uterus and placental labyrinth","volume":"260","author":"Vermeirsch","year":"2000","journal-title":"Anat Rec"},{"key":"2019070503124678100_bib28","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1530\/REP-09-0140","article-title":"Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition","volume":"139","author":"Kowalewski","year":"2010","journal-title":"Reproduction"},{"issue":"Suppl 1","key":"2019070503124678100_bib29","doi-asserted-by":"crossref","first-page":"S96","DOI":"10.1093\/bioinformatics\/18.suppl_1.S96","article-title":"Variance stabilization applied to microarray data calibration and to the quantification of differential expression","volume":"18","author":"Huber","year":"2002","journal-title":"Bioinformatics"},{"key":"2019070503124678100_bib30","doi-asserted-by":"crossref","first-page":"3705","DOI":"10.1093\/bioinformatics\/bth449","article-title":"limmaGUI: a graphical user interface for linear modeling of microarray data","volume":"20","author":"Wettenhall","year":"2004","journal-title":"Bioinformatics"},{"key":"2019070503124678100_bib31","doi-asserted-by":"crossref","first-page":"P3","DOI":"10.1186\/gb-2003-4-5-p3","article-title":"DAVID: Database for annotation, visualization, and integrated discovery","volume":"4","author":"Dennis","year":"2003","journal-title":"Genome Biol"},{"key":"2019070503124678100_bib32","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res"},{"key":"2019070503124678100_bib33","volume-title":"Reproduction in Domestic Ruminants VIII: Proceedings of the Ninth International Symposium on Reproduction in Domestic Ruminants, Obihiro, Hokkaido, Japan, August 2014.","author":"Juengel","year":"2014"},{"key":"2019070503124678100_bib34","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1095\/biolreprod.113.112177","article-title":"Transcriptome changes in the porcine endometrium during the pre-attachment phase","volume":"89","author":"Samborski","year":"2013","journal-title":"Biol Reprod"},{"key":"2019070503124678100_bib35","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1095\/biolreprod.110.085233","article-title":"Microarray analysis of equine endometrium at days 8 and 12 of pregnancy","volume":"83","author":"Merkl","year":"2010","journal-title":"Biol Reprod"},{"key":"2019070503124678100_bib36","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc Natl Acad Sci"},{"key":"2019070503124678100_bib37","article-title":"Venny. An interactive tool for comparing lists with Venn Diagrams","author":"Oliveros","year":"2207-2015"},{"key":"2019070503124678100_bib38","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1210\/me.2011-1196","article-title":"Research resource: interactome of human embryo implantation: identification of gene expression pathways, regulation, and integrated regulatory networks","volume":"26","author":"Altmae","year":"2012","journal-title":"Mol Endocrinol"},{"key":"2019070503124678100_bib39","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s12958-015-0066-4","article-title":"In vitro decidualisation of canine uterine stromal cells","volume":"13","author":"Kautz","year":"2015","journal-title":"Reprod Biol Endocrinol"},{"key":"2019070503124678100_bib40","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.theriogenology.2010.10.030","article-title":"Expression and functional implications of peroxisome proliferator-activated receptor gamma (PPARgamma) in canine reproductive tissues during normal pregnancy and parturition and at antiprogestin induced abortion","volume":"75","author":"Kowalewski","year":"2011","journal-title":"Theriogenology"},{"key":"2019070503124678100_bib41","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/biolreprod\/5.2.194","article-title":"The prenatal development of the dog: pre-implantation events","volume":"5","author":"Holst","year":"1971","journal-title":"Biol Reprod"},{"issue":"Suppl 2","key":"2019070503124678100_bib42","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1439-0531.2009.01414.x","article-title":"Endocrinologic control of normal canine ovarian function","volume":"44","author":"Concannon","year":"2009","journal-title":"Reprod Domest Anim"},{"key":"2019070503124678100_bib43","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/BF00519908","article-title":"Chorionic development and structure of the placenta zonaria in the cat, dog and fox (author's transl)","volume":"143","author":"Kehrer","year":"1973","journal-title":"Z Anat Entwicklungsgesch"},{"key":"2019070503124678100_bib44","first-page":"127","article-title":"Placentation","volume-title":"Marshall's Physiology of Reproduction","author":"Amoroso","year":"1952"},{"key":"2019070503124678100_bib45","doi-asserted-by":"crossref","first-page":"21785","DOI":"10.1074\/jbc.R000003200","article-title":"Ligand binding to integrins","volume":"275","author":"Plow","year":"2000","journal-title":"J Biol Chem"},{"key":"2019070503124678100_bib46","first-page":"643","article-title":"Aberrant integrin expression in the endometrium of women with endometriosis","volume":"79","author":"Lessey","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"2019070503124678100_bib47","doi-asserted-by":"crossref","first-page":"253","DOI":"10.2478\/v10181-011-0038-3","article-title":"Analysis of integrins and vascular endothelial growth factor isoforms mRNA expression in the canine uterus during perimplantation period","volume":"14","author":"Bukowska","year":"2011","journal-title":"Pol J Vet Sci"},{"key":"2019070503124678100_bib48","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1091\/mbc.1.10.731","article-title":"Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits","volume":"1","author":"Engvall","year":"1990","journal-title":"Cell Regul"},{"key":"2019070503124678100_bib49","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/BF00221758","article-title":"An immunohistochemical study of human endometrial extracellular matrix during the menstrual cycle and first trimester of pregnancy","volume":"253","author":"Aplin","year":"1988","journal-title":"Cell Tissue Res"},{"key":"2019070503124678100_bib50","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1093\/humrep\/der075","article-title":"Transcriptome analysis reveals dialogues between human trophectoderm and endometrial cells during the implantation period","volume":"26","author":"Haouzi","year":"2011","journal-title":"Hum Reprod"},{"key":"2019070503124678100_bib51","doi-asserted-by":"crossref","first-page":"D200","DOI":"10.1093\/nar\/gkw1129","article-title":"CDD\/SPARCLE: functional classification of proteins via subfamily domain architectures","volume":"45","author":"Marchler-Bauer","year":"2017","journal-title":"Nucleic Acids Res"},{"key":"2019070503124678100_bib52","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1210\/endo.131.5.1425413","article-title":"Progesterone control of fibronectin secretion in guinea pig endometrium","volume":"131","author":"Mularoni","year":"1992","journal-title":"Endocrinology"},{"key":"2019070503124678100_bib53","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1083\/jcb.94.3.597","article-title":"Fibronectin and cell shape in vivo: studies on the endometrium during pregnancy","volume":"94","author":"Grinnell","year":"1982","journal-title":"J Cell Biol"},{"issue":"Suppl A","key":"2019070503124678100_bib54","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1053\/plac.2000.0521","article-title":"Paracrine and autocrine regulators of trophoblast invasion\u2013a review","volume":"21","author":"Bischof","year":"2000","journal-title":"Placenta"},{"key":"2019070503124678100_bib55","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1530\/REP-09-0341","article-title":"Interleukin-8 (CXCL8) stimulates trophoblast cell migration and invasion by increasing levels of matrix metalloproteinase (MMP)2 and MMP9 and integrins alpha5 and beta1","volume":"139","author":"Jovanovic","year":"2010","journal-title":"Reproduction"},{"key":"2019070503124678100_bib56","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1111\/j.1439-0531.2006.00838.x","article-title":"Matrix metalloproteinase (MMP)-2 and MMP-9 activity in the canine uterus before and during placentation","volume":"42","author":"Beceriklisoy","year":"2007","journal-title":"Reprod Domest Anim"},{"key":"2019070503124678100_bib57","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/j.1439-0531.2007.00966.x","article-title":"Expression of genes in the canine pre-implantation uterus and embryo: implications for an active role of the embryo before and during invasion","volume":"43","author":"Schafer-Somi","year":"2008","journal-title":"Reprod Domest Anim"},{"key":"2019070503124678100_bib58","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0014-5793(94)80250-5","article-title":"Progesterone increases the production of tissue inhibitor of metalloproteinases-2 in rabbit uterine cervical fibroblasts","volume":"341","author":"Imada","year":"1994","journal-title":"FEBS Lett"},{"key":"2019070503124678100_bib59","doi-asserted-by":"crossref","first-page":"773","DOI":"10.7150\/ijms.11610","article-title":"Progesterone Inhibits Leptin-Induced Invasiveness of BeWo Cells","volume":"12","author":"Jo","year":"2015","journal-title":"Int J Med Sci"},{"key":"2019070503124678100_bib60","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ando.2016.04.015","article-title":"PAPP-A and the IGF system","volume":"77","author":"Monget","year":"2016","journal-title":"Ann Endocrinol (Paris)"},{"key":"2019070503124678100_bib61","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ando.2013.02.003","article-title":"Cross-talk between insulin signaling and cell proliferation pathways","volume":"74","author":"Burnol","year":"2013","journal-title":"Ann Endocrinol (Paris)"},{"key":"2019070503124678100_bib62","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.mce.2014.01.023","article-title":"Insulin-like growth factor I induces proliferation and migration of porcine trophectoderm cells through multiple cell signaling pathways, including protooncogenic protein kinase 1 and mitogen-activated protein kinase","volume":"384","author":"Jeong","year":"2014","journal-title":"Mol Cell Endocrinol"},{"key":"2019070503124678100_bib63","first-page":"442","article-title":"The effects of progesterone and insulin-like growth factor (IGF- I and IGF-II) on proliferation in human decidual stromal cells of early pregnancy in vitro","volume":"40","author":"Li","year":"2009","journal-title":"Sichuan Da Xue Xue Bao Yi Xue Ban"},{"key":"2019070503124678100_bib64","doi-asserted-by":"crossref","first-page":"4173","DOI":"10.1210\/en.2007-0268","article-title":"The postimplantation embryo differentially regulates endometrial gene expression and decidualization","volume":"148","author":"Kashiwagi","year":"2007","journal-title":"Endocrinology"},{"key":"2019070503124678100_bib65","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.placenta.2006.04.006","article-title":"New light on early post-implantation pregnancy in the mouse: roles for insulin-like growth factor-II (IGF-II)?","volume":"28","author":"Pringle","year":"2007","journal-title":"Placenta"},{"key":"2019070503124678100_bib66","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0960-9822(98)70082-X","article-title":"Nuclear localization signal-independent and importin\/karyopherin-independent nuclear import of beta-catenin","volume":"8","author":"Fagotto","year":"1998","journal-title":"Curr Biol"},{"key":"2019070503124678100_bib67","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/emboj\/21.3.377","article-title":"Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains","volume":"21","author":"Jakel","year":"2002","journal-title":"Embo J"},{"key":"2019070503124678100_bib68","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.placenta.2010.07.011","article-title":"Wnt signalling in implantation, decidualisation and placental differentiation\u2013review","volume":"31","author":"Sonderegger","year":"2010","journal-title":"Placenta"},{"key":"2019070503124678100_bib69","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.4049\/jimmunol.1201925","article-title":"Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-epsilon expression","volume":"191","author":"Matsumiya","year":"2013","journal-title":"J Immunol"},{"key":"2019070503124678100_bib70","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.ygeno.2004.03.003","article-title":"Characterization of the type I interferon locus and identification of novel genes","volume":"84","author":"Hardy","year":"2004","journal-title":"Genomics"},{"key":"2019070503124678100_bib71","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1111\/j.1742-4658.2011.08079.x","article-title":"Targeted disruption of one of the importin alpha family members leads to female functional incompetence in delivery","volume":"278","author":"Moriyama","year":"2011","journal-title":"Febs j"},{"key":"2019070503124678100_bib72","first-page":"604","article-title":"Increased importin 13 activity is associated with the pathogenesis of pterygium","volume":"19","author":"Xu","year":"2013","journal-title":"Mol Vis"},{"key":"2019070503124678100_bib73","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/tra.12174","article-title":"Biological significance of the importin-beta family-dependent nucleocytoplasmic transport pathways","volume":"15","author":"Kimura","year":"2014","journal-title":"Traffic"},{"key":"2019070503124678100_bib74","doi-asserted-by":"crossref","first-page":"26725","DOI":"10.1016\/S0021-9258(19)74373-7","article-title":"A serum-derived hyaluronan-associated protein (SHAP) is the heavy chain of the inter alpha-trypsin inhibitor","volume":"268","author":"Huang","year":"1993","journal-title":"J Biol Chem"},{"key":"2019070503124678100_bib75","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0014-5793(95)00882-A","article-title":"The major acute phase serum protein in pigs is homologous to human plasma kallikrein sensitive PK-120","volume":"371","author":"Gonzalez-Ramon","year":"1995","journal-title":"FEBS Lett"},{"key":"2019070503124678100_bib76","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1530\/rep.0.1260621","article-title":"Expression of inter-alpha-trypsin inhibitor heavy chains in endometrium of cyclic and pregnant gilts","volume":"126","author":"Geisert","year":"2003","journal-title":"Reproduction"},{"key":"2019070503124678100_bib77","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/PL00000211","article-title":"The novel acute phase protein, IHRP, inhibits actin polymerization and phagocytosis of polymorphonuclear cells","volume":"49","author":"Choi-Miura","year":"2000","journal-title":"Inflamm Res"},{"key":"2019070503124678100_bib78","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1038\/nrd3599","article-title":"Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets","volume":"10","author":"Jun","year":"2011","journal-title":"Nat Rev Drug Discov"},{"key":"2019070503124678100_bib79","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.tibs.2008.07.006","article-title":"The CCN family of proteins: structure-function relationships","volume":"33","author":"Holbourn","year":"2008","journal-title":"Trends Biochem Sci"},{"key":"2019070503124678100_bib80","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1007\/s00018-014-1556-9","article-title":"The role of the CCN family of proteins in female reproduction","volume":"71","author":"Winterhager","year":"2014","journal-title":"Cell Mol Life Sci"},{"key":"2019070503124678100_bib81","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s12185-014-1534-x","article-title":"Nov\/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin alphavbeta3","volume":"99","author":"Ishihara","year":"2014","journal-title":"Int J Hematol"},{"key":"2019070503124678100_bib82","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1093\/molehr\/gal044","article-title":"Decreased expression of the angiogenic regulators CYR61 (CCN1) and NOV (CCN3) in human placenta is associated with pre-eclampsia","volume":"12","author":"Gellhaus","year":"2006","journal-title":"Mol Hum Reprod"},{"key":"2019070503124678100_bib83","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9","article-title":"The Ki-67 protein: from the known and the unknown","volume":"182","author":"Scholzen","year":"2000","journal-title":"J Cell Physiol"},{"key":"2019070503124678100_bib84","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.4049\/jimmunol.133.4.1710","article-title":"Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67","volume":"133","author":"Gerdes","year":"1984","journal-title":"J Immunol"},{"key":"2019070503124678100_bib85","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1365-2184.2007.00433.x","article-title":"Chromophore-assisted light inactivation of pKi-67 leads to inhibition of ribosomal RNA synthesis","volume":"40","author":"Rahmanzadeh","year":"2007","journal-title":"Cell Prolif"},{"key":"2019070503124678100_bib86","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/ncb1693","article-title":"Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2","volume":"10","author":"Ji","year":"2008","journal-title":"Nat Cell Biol"},{"key":"2019070503124678100_bib87","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1146\/annurev.biochem.75.103004.142647","article-title":"Mechanism and function of formins in the control of actin assembly","volume":"76","author":"Goode","year":"2007","journal-title":"Annu Rev Biochem"},{"key":"2019070503124678100_bib88","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1038\/ncb1745","article-title":"WAVE and Arp2\/3 jointly inhibit filopodium formation by entering into a complex with mDia2","volume":"10","author":"Beli","year":"2008","journal-title":"Nat Cell Biol"},{"key":"2019070503124678100_bib89","doi-asserted-by":"crossref","first-page":"4646","DOI":"10.1091\/mbc.E15-09-0626","article-title":"Cell type-dependent mechanisms for formin-mediated assembly of filopodia","volume":"26","author":"Young","year":"2015","journal-title":"Mol Biol Cell"},{"key":"2019070503124678100_bib90","doi-asserted-by":"crossref","first-page":"e317","DOI":"10.1371\/journal.pbio.0050317","article-title":"Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells","volume":"5","author":"Yang","year":"2007","journal-title":"PLoS Biol"},{"key":"2019070503124678100_bib91","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.yexcr.2006.10.033","article-title":"RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking","volume":"313","author":"Wallar","year":"2007","journal-title":"Exp Cell Res"},{"key":"2019070503124678100_bib92","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1091\/mbc.e07-10-1086","article-title":"mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells","volume":"19","author":"Watanabe","year":"2008","journal-title":"Mol Biol Cell"},{"key":"2019070503124678100_bib93","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.cub.2007.03.024","article-title":"Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex","volume":"17","author":"Eisenmann","year":"2007","journal-title":"Curr Biol"},{"key":"2019070503124678100_bib94","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1158\/0008-5472.CAN-08-3709","article-title":"Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells","volume":"69","author":"Lizarraga","year":"2009","journal-title":"Cancer Res"},{"key":"2019070503124678100_bib95","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1091\/mbc.e13-08-0482","article-title":"Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration","volume":"25","author":"Daou","year":"2014","journal-title":"Mol Biol Cell"},{"key":"2019070503124678100_bib96","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/nrm2816","article-title":"Unleashing formins to remodel the actin and microtubule cytoskeletons","volume":"11","author":"Chesarone","year":"2010","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2019070503124678100_bib97","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10555-008-9170-7","article-title":"Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion","volume":"28","author":"Narumiya","year":"2009","journal-title":"Cancer Metastasis Rev"},{"key":"2019070503124678100_bib98","doi-asserted-by":"crossref","first-page":"5601","DOI":"10.1158\/0008-5472.CAN-08-3860","article-title":"Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease","volume":"69","author":"Di Vizio","year":"2009","journal-title":"Cancer Res"},{"key":"2019070503124678100_bib99","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1051\/animres:19920321","article-title":"Pregnancy diagnosis in the bitch: the development of a test based on the measurement of acute phase proteins in the blood","volume":"41","author":"Evans","year":"1992","journal-title":"Annales De Zootechnie"},{"key":"2019070503124678100_bib100","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.2460\/ajvr.1996.57.09.1382","article-title":"Postimplantation increase in plasma fibrinogen concentration with increase in relaxin concentration in pregnant dogs","volume":"57","author":"Concannon","year":"1996","journal-title":"Am J Vet Res"},{"key":"2019070503124678100_bib101","first-page":"159","article-title":"Acute phase proteins in canine pregnancy (Canis familiaris)","volume":"47","author":"Eckersall","year":"1993","journal-title":"J Reprod Fertil Suppl"},{"key":"2019070503124678100_bib102","doi-asserted-by":"crossref","first-page":"5784","DOI":"10.1016\/S0021-9258(18)83618-3","article-title":"The expression of alpha(1)-acid glycoprotein mRNA during rat development. High levels of expression in the decidua","volume":"264","author":"Thomas","year":"1989","journal-title":"J Biol Chem"},{"key":"2019070503124678100_bib103","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0378(89)90002-8","article-title":"Cytokine networks in the uteroplacental unit: macrophages as pivotal regulatory cells","volume":"16","author":"Hunt","year":"1989","journal-title":"J Reprod Immunol"},{"key":"2019070503124678100_bib104","first-page":"429","article-title":"The secretory immune system as part of the placental barrier in the second trimester of pregnancy in humans","volume":"15","author":"Ben-Hur","year":"2001","journal-title":"In Vivo"},{"key":"2019070503124678100_bib105","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1600-0897.2004.00156.x","article-title":"Macrophages and apoptotic cell clearance during pregnancy","volume":"51","author":"Abrahams","year":"2004","journal-title":"Am J Reprod Immunol"},{"key":"2019070503124678100_bib106","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/mi.2008.5","article-title":"Mucins in the mucosal barrier to infection","volume":"1","author":"Linden","year":"2008","journal-title":"Mucosal Immunol"},{"key":"2019070503124678100_bib107","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/1477-7827-1-116","article-title":"Innate immune defences in the human endometrium","volume":"1","author":"King","year":"2003","journal-title":"Reprod Biol Endocrinol"},{"key":"2019070503124678100_bib108","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0003-9861(76)90461-6","article-title":"Progesterone induction of lysozyme and peptidase activities in the porcine uterus","volume":"177","author":"Roberts","year":"1976","journal-title":"Arch Biochem Biophys"},{"key":"2019070503124678100_bib109","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1093\/molehr\/gah246","article-title":"IDO expression on decidual and peripheral blood dendritic cells and monocytes\/macrophages after treatment with CTLA-4 or interferon-gamma increase in normal pregnancy but decrease in spontaneous abortion","volume":"11","author":"Miwa","year":"2005","journal-title":"Mol Hum Reprod"},{"key":"2019070503124678100_bib110","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1084\/jem.189.9.1363","article-title":"Inhibition of\u2009 T cell proliferation by macrophage tryptophan catabolism","volume":"189","author":"Munn","year":"1999","journal-title":"J Exp Med"},{"key":"2019070503124678100_bib111","doi-asserted-by":"crossref","first-page":"3596","DOI":"10.4049\/jimmunol.164.7.3596","article-title":"Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation","volume":"164","author":"Hwu","year":"2000","journal-title":"J Immunol"},{"key":"2019070503124678100_bib112","doi-asserted-by":"crossref","first-page":"5953","DOI":"10.4049\/jimmunol.1001628","article-title":"IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis","volume":"185","author":"Yan","year":"2010","journal-title":"J Immunol"},{"key":"2019070503124678100_bib113","doi-asserted-by":"crossref","first-page":"e89006","DOI":"10.1371\/journal.pone.0089006","article-title":"Stromal cells from human decidua exert a strong inhibitory effect on NK cell function and dendritic cell differentiation","volume":"9","author":"Croxatto","year":"2014","journal-title":"PLoS One"},{"key":"2019070503124678100_bib114","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.1600-0897.2004.00217.x","article-title":"The immune environment in human endometrium during the window of implantation","volume":"52","author":"Lobo","year":"2004","journal-title":"Am J Reprod Immunol"},{"key":"2019070503124678100_bib115","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1572-0241.2004.40012.x-i1","article-title":"Comparative effects of L-tryptophan and 1-methyl-tryptophan on immunoregulation induced by sperm, human pre-implantation embryo and trophoblast supernatants","volume":"50","author":"Gutierrez","year":"2003","journal-title":"Am J Reprod Immunol"},{"key":"2019070503124678100_bib116","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1093\/humupd\/6.1.28","article-title":"Uterine leukocytes and decidualization","volume":"6","author":"King","year":"2000","journal-title":"Hum Reprod Update"},{"key":"2019070503124678100_bib117","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1387\/ijdb.082763jb","article-title":"Immune cells in the placental bed","volume":"54","author":"Bulmer","year":"2010","journal-title":"Int J Dev Biol"},{"key":"2019070503124678100_bib118","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nri1897","article-title":"Immunology of placentation in eutherian mammals","volume":"6","author":"Moffett","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"2019070503124678100_bib119","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.cellimm.2013.07.008","article-title":"Role of AIF-1 in the regulation of inflammatory activation and diverse disease processes","volume":"284","author":"Zhao","year":"2013","journal-title":"Cell Immunol"},{"key":"2019070503124678100_bib120","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1080\/08916930601083946","article-title":"Allograft inflammatory factor-1 and its immune regulation","volume":"40","author":"Liu","year":"2007","journal-title":"Autoimmunity"},{"key":"2019070503124678100_bib121","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1161\/01.ATV.0000130024.50058.de","article-title":"AIF-1 expression modulates proliferation of human vascular smooth muscle cells by autocrine expression of G-CSF","volume":"24","author":"Chen","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2019070503124678100_bib122","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1203\/PDR.0b013e3181bf572b","article-title":"Overexpression of allograft inflammatory factor-1 promotes the proliferation and migration of human endothelial cells (HUV-EC-C) probably by up-regulation of basic fibroblast growth factor","volume":"67","author":"Jia","year":"2010","journal-title":"Pediatr Res"},{"key":"2019070503124678100_bib123","doi-asserted-by":"crossref","first-page":"C256","DOI":"10.1152\/ajpcell.00325.2008","article-title":"AIF-1 expression regulates endothelial cell activation, signal transduction, and vasculogenesis","volume":"296","author":"Tian","year":"2009","journal-title":"Am J Physiol Cell Physiol"},{"key":"2019070503124678100_bib124","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1172\/JCI118003","article-title":"Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection","volume":"95","author":"Utans","year":"1995","journal-title":"J Clin Invest"},{"key":"2019070503124678100_bib125","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1034\/j.1600-0897.2003.00060.x","article-title":"Expression of allograft inflammatory factor-1 in mouse uterus and poly(I:C)-induced fetal resorption","volume":"50","author":"Shimada","year":"2003","journal-title":"Am J Reprod Immunol"},{"key":"2019070503124678100_bib126","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1530\/ror.0.0030052","article-title":"Cytokines and implantation","volume":"3","author":"Sharkey","year":"1998","journal-title":"Rev Reprod"},{"key":"2019070503124678100_bib127","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0012-1606(91)90236-V","article-title":"Cytokines modulate pre-implantation development and pregnancy","volume":"146","author":"Tartakovsky","year":"1991","journal-title":"Dev Biol"},{"key":"2019070503124678100_bib128","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0165-0378(98)00017-5","article-title":"Cytokines and embryo implantation1","volume":"39","author":"Sim\u00f3n","year":"1998","journal-title":"J Reprod Immunol"},{"key":"2019070503124678100_bib129","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1097\/FJC.0b013e318093ec8f","article-title":"Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha\/CXCR4 via PI3K\/Akt\/eNOS signal transduction pathway","volume":"50","author":"Zheng","year":"2007","journal-title":"J Cardiovasc Pharmacol"},{"key":"2019070503124678100_bib130","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/79738","article-title":"A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo","volume":"1","author":"Matloubian","year":"2000","journal-title":"Nat Immunol"},{"key":"2019070503124678100_bib131","first-page":"399","article-title":"[Expressions of CXCL16\/CXCR6 and CXCL12\/CXCR4 in first-trimester human trophoblast cells]","volume":"41","author":"Huang","year":"2006","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"2019070503124678100_bib132","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1093\/humrep\/dei436","article-title":"Chemokine CXCL16, a scavenger receptor, induces proliferation and invasion of first-trimester human trophoblast cells in an autocrine manner","volume":"21","author":"Huang","year":"2006","journal-title":"Hum Reprod"},{"key":"2019070503124678100_bib133","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jri.2011.01.016","article-title":"CXCR7 and syndecan-4 are potential receptors for CXCL12 in human cytotrophoblasts","volume":"89","author":"Schanz","year":"2011","journal-title":"J Reprod Immunol"},{"key":"2019070503124678100_bib134","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1111\/j.1471-0528.1986.tb07834.x","article-title":"Prostaglandin D2 release by endometrium and myometrium","volume":"93","author":"Rees","year":"1986","journal-title":"Br J Obstet Gynaecol"},{"key":"2019070503124678100_bib135","first-page":"440","article-title":"Prostaglandin D2 production by term human decidua: cellular origins defined using flow cytometry","volume":"80","author":"Norwitz","year":"1992","journal-title":"Obstet Gynecol"},{"key":"2019070503124678100_bib136","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1084\/jem.193.2.255","article-title":"Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2","volume":"193","author":"Hirai","year":"2001","journal-title":"J Exp Med"},{"key":"2019070503124678100_bib137","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1093\/molehr\/8.2.181","article-title":"Accumulation of CRTH2-positive T-helper 2 and T-cytotoxic 2 cells at implantation sites of human decidua in a prostaglandin D(2)-mediated manner","volume":"8","author":"Michimata","year":"2002","journal-title":"Mol Hum Reprod"},{"key":"2019070503124678100_bib138","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1034\/j.1600-0897.2002.01113.x","article-title":"Prostaglandin D2 and reproduction","volume":"47","author":"Saito","year":"2002","journal-title":"Am J Reprod Immunol"},{"key":"2019070503124678100_bib139","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/01.shk.0000223121.03523.69","article-title":"Synergistic effect of peroxisome proliferator activated receptor-gamma and liver X receptor-alpha in the regulation of inflammation in macrophages","volume":"26","author":"Piraino","year":"2006","journal-title":"Shock"},{"key":"2019070503124678100_bib140","doi-asserted-by":"crossref","first-page":"6207","DOI":"10.1073\/pnas.0306743102","article-title":"Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance","volume":"102","author":"Jones","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2019070503124678100_bib141","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1463-1326.2007.00708.x","article-title":"Pomegranate flower: a unique traditional antidiabetic medicine with dual PPAR-alpha\/-gamma activator properties","volume":"10","author":"Li","year":"2008","journal-title":"Diabetes Obes Metab"},{"key":"2019070503124678100_bib142","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1095\/biolreprod.104.039032","article-title":"Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells","volume":"73","author":"Ackerman","year":"2005","journal-title":"Biol Reprod"},{"key":"2019070503124678100_bib143","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.theriogenology.2009.09.020","article-title":"Prostaglandin-D synthetase induces transcription of the LH beta subunit in the primary culture of chicken anterior pituitary cells via the PPAR signaling pathway","volume":"73","author":"Chen","year":"2010","journal-title":"Theriogenology"},{"key":"2019070503124678100_bib144","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1071\/RD9890237","article-title":"Establishment of pregnancy in sheep and pigs","volume":"1","author":"Bazer","year":"1989","journal-title":"Reprod Fertil Dev"},{"issue":"Suppl 2","key":"2019070503124678100_bib145","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1439-0531.2009.01414.x","article-title":"Endocrinologic control of normal canine ovarian function","volume":"44","author":"Concannon","year":"2009","journal-title":"Reprod Domest Anim"},{"key":"2019070503124678100_bib146","first-page":"169","article-title":"Embryo development, hormonal requirements and maternal responses during canine pregnancy","volume":"57","author":"Concannon","year":"2001","journal-title":"J Reprod Fertil Suppl"},{"key":"2019070503124678100_bib147","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/978-3-319-15856-3_10","article-title":"Implantation and Establishment of Pregnancy in Human and Nonhuman Primates","volume":"216","author":"Su","year":"2015","journal-title":"Adv Anat Embryol Cell Biol"},{"key":"2019070503124678100_bib148","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1055\/s-2007-991042","article-title":"Decidualization of the human endometrium: mechanisms, functions, and clinical perspectives","volume":"25","author":"Gellersen","year":"2007","journal-title":"Semin Reprod Med"},{"key":"2019070503124678100_bib149","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1210\/er.2014-1045","article-title":"Cyclic decidualization of the human endometrium in reproductive health and failure","volume":"35","author":"Gellersen","year":"2014","journal-title":"Endocr Rev"},{"key":"2019070503124678100_bib150","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1210\/endo-122-4-1466","article-title":"Estrous cycle- and pregnancy-related differences in expression of the proenkephalin and proopiomelanocortin genes in the ovary and uterus","volume":"122","author":"Jin","year":"1988","journal-title":"Endocrinology"},{"key":"2019070503124678100_bib151","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1095\/biolreprod59.4.925","article-title":"Expression of opioid receptors and ligands in pregnant mouse uterus and placenta","volume":"59","author":"Zhu","year":"1998","journal-title":"Biol Reprod"},{"key":"2019070503124678100_bib152","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/jcp.22056","article-title":"Retinoic acid-metabolizing enzyme cytochrome P450 26a1 (cyp26a1) is essential for implantation: functional study of its role in early pregnancy","volume":"223","author":"Han","year":"2010","journal-title":"J Cell Physiol"},{"key":"2019070503124678100_bib153","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1093\/humrep\/deq268","article-title":"Retinoic acid metabolizing enzyme CYP26A1 is implicated in rat embryo implantation","volume":"25","author":"Xia","year":"2010","journal-title":"Hum Reprod"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/97\/2\/197\/28905511\/iox063.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T23:04:03Z","timestamp":1719270243000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article\/97\/2\/197\/3884624"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,23]]},"references-count":153,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,6,23]]},"published-print":{"date-parts":[[2017,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/biolre\/iox063","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,8]]},"published":{"date-parts":[[2017,6,23]]}}}