{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:39:13Z","timestamp":1791891553200,"version":"4.3.4"},"reference-count":91,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2002,2,1]],"date-time":"2002-02-01T00:00:00Z","timestamp":1012521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,12,4]],"date-time":"2017-12-04T00:00:00Z","timestamp":1512345600000},"content-version":"vor","delay-in-days":5785,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Anaesthesia"],"published-print":{"date-parts":[[2002,2]]},"DOI":"10.1093\/bja\/88.2.199","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T18:28:32Z","timestamp":1027708112000},"page":"199-214","source":"Crossref","is-referenced-by-count":370,"title":["Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review"],"prefix":"10.1016","volume":"88","author":[{"given":"M.","family":"Hyllested","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.L.","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Kehlet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/bja\/88.2.199_bib1","first-page":"1","article-title":"Single dose oral ibuprofen and diclofenac for postoperative pain","author":"Collins","year":"1998","journal-title":"Cochrane Systematic Rev"},{"key":"10.1093\/bja\/88.2.199_bib2","first-page":"1","article-title":"Single dose paracetamol (acetaminophen), with and without codeine, for postoperative pain","author":"Moore","year":"1998","journal-title":"Cochrane Systematic Rev"},{"key":"10.1093\/bja\/88.2.199_bib3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1366-0071(99)80006-0","article-title":"Paracetamol revisited: a review of the pharmacokinetics and pharmacodynamics","volume":"2","author":"Ward","year":"1999","journal-title":"Acute Pain"},{"key":"10.1093\/bja\/88.2.199_bib4","first-page":"469","article-title":"Paracetamol and propacetamol for post-operative pain: contrasts to traditional NSAIDs. Bailli\u00e8re's","volume":"9","author":"Wiebalck","year":"1995","journal-title":"Clin Anaesthesiol"},{"key":"10.1093\/bja\/88.2.199_bib5","first-page":"119","article-title":"The efficacy of nonopioid analgesics for postoperative dental pain: a meta-analysis","volume":"44","author":"Ahmad","year":"1997","journal-title":"Anesth Prog"},{"key":"10.1093\/bja\/88.2.199_bib6","series-title":"An Evidence-Based Resource for Pain Relief","first-page":"10","article-title":"Judging the quality of trials","author":"McQuay","year":"1998"},{"key":"10.1093\/bja\/88.2.199_bib7","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0304-3959(96)03319-2","article-title":"Paracetamol with and without codeine in acute pain: a quantitative systematic review","volume":"70","author":"Moore","year":"1997","journal-title":"Pain"},{"issue":"Suppl 2","key":"10.1093\/bja\/88.2.199_bib8","doi-asserted-by":"crossref","first-page":"355S","DOI":"10.1111\/j.1365-2125.1980.tb01823.x","article-title":"Clinical efficacy of mild analgesics in pain following gynaecological or dental surgery: report on multicentre studies","volume":"10","author":"Gomez-Jimenez","year":"1980","journal-title":"Br J Clin Pharmacol"},{"key":"10.1093\/bja\/88.2.199_bib9","series-title":"Mortality in Anaesthesia","first-page":"196","article-title":"Relief of postoperative pain with zomepirac, paracetamol with codeine, or placebo","author":"Breivik","year":"1983"},{"key":"10.1093\/bja\/88.2.199_bib10","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/bja\/39.2.146","article-title":"A comparison of aspirin and paracetamol","volume":"39","author":"Parkhouse","year":"1967","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib11","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1302\/0301-620X.66B2.6546760","article-title":"Open meniscectomy: enhanced recovery after synovial prostaglandin inhibition","volume":"66","author":"Muckle","year":"1984","journal-title":"J Bone Joint Surg Br"},{"key":"10.1093\/bja\/88.2.199_bib12","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1093\/bja\/50.9.931","article-title":"Comparative assessment of fenoprofen and paracetamol given in combination for pain after surgery","volume":"50","author":"Davie","year":"1978","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib13","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0099-2399(06)80098-1","article-title":"Effectiveness of various medications on postoperative pain following complete instrumentation","volume":"20","author":"Torabinejad","year":"1994","journal-title":"J Endodon"},{"key":"10.1093\/bja\/88.2.199_bib14","first-page":"65","article-title":"The analgesic effect of preoperative administration of propacetamol, tenoxicam or a mixture of both in arthroscopic, outpatient knee surgery","volume":"50","author":"VanLancker","year":"1999","journal-title":"Acta Anaesthesiol Belg"},{"key":"10.1093\/bja\/88.2.199_bib15","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1090-3801(97)90050-1","article-title":"No analgesic effect of ibuprofen or paracetamol vs placebo for hysterectomies","volume":"1","author":"Dahl","year":"1997","journal-title":"Eur J Pain"},{"key":"10.1093\/bja\/88.2.199_bib16","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00005537-199801000-00018","article-title":"Tube placement: a prospective, randomized double-blind study","volume":"108","author":"Derkay","year":"1998","journal-title":"Laryngoscope"},{"key":"10.1093\/bja\/88.2.199_bib17","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/bja\/77.4.445","article-title":"Morphine consumption in patients receiving rectal paracetamol and diclofenac alone and in combination","volume":"77","author":"Montgomery","year":"1996","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib18","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1213\/00000539-199903000-00028","article-title":"A double-blinded evaluation of propacetamol versus ketorolac in combination with patient-controlled analgesia morphine: analgesic efficacy and tolerability after gynecologic surgery","volume":"88","author":"Varrassi","year":"1999","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/88.2.199_bib19","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/j.1399-6576.1992.tb03475.x","article-title":"Application of sublingual buprenorphine in combination with naproxen or paracetamol for post-operative pain relief in cholecystectomy patients in a double-blind study","volume":"36","author":"Witjes","year":"1992","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1093\/bja\/88.2.199_bib20","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/bja\/83.2.253","article-title":"Rectal paracetamol has a significant morphine-sparing effect after hysterectomy","volume":"83","author":"Cobby","year":"1999","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib21","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3109\/13645709709153328","article-title":"Pain control in the week following laparoscopic surgery: a comparison of sustained-release ibuprofen and paracetamol","volume":"6","author":"Owen","year":"1997","journal-title":"Min Invasive Ther Allied Technol"},{"key":"10.1093\/bja\/88.2.199_bib22","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/clpt.1986.15","article-title":"Ketorolac and acetaminophen for orthopedic postoperative pain","volume":"39","author":"McQuay","year":"1986","journal-title":"Clin Pharmacol Ther"},{"key":"10.1093\/bja\/88.2.199_bib23","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1038\/clpt.1990.105","article-title":"Bromfenac, acetaminophen, and placebo in orthopedic postoperative pain","volume":"47","author":"McQuay","year":"1990","journal-title":"Clin Pharmacol Ther"},{"key":"10.1093\/bja\/88.2.199_bib24","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/BF03011934","article-title":"Postoperative analgesia with i.v. propacetamol and ketoprofen combination after disc surgery","volume":"44","author":"Fletcher","year":"1997","journal-title":"Can J Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib25","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1002\/j.1552-4604.1989.tb03380.x","article-title":"Ibuprofen and acetaminophen in the relief of postpartum episiotomy pain","volume":"29","author":"Schachtel","year":"1989","journal-title":"J Clin Pharmacol"},{"key":"10.1093\/bja\/88.2.199_bib26","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/BF00265841","article-title":"Comparison of postpartum pain treatments using a sequential trial design: II. Naproxen versus paracetamol","volume":"40","author":"Skovlund","year":"1991","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1093\/bja\/88.2.199_bib27","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/0002-9378(86)90291-7","article-title":"Effects of meclofenamate and acetaminophen on abdominal pain following tubal occlusion","volume":"155","author":"Huang","year":"1986","journal-title":"Am J Obstet Gynecol"},{"key":"10.1093\/bja\/88.2.199_bib28","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1046\/j.1460-9592.1997.d01-47.x","article-title":"Acetaminophen or ketorolac for post myringotomy pain in children? A prospective, double-blinded comparison","volume":"7","author":"Bean-Lijewski","year":"1997","journal-title":"Paediatr Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib29","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1111\/j.1365-2044.1992.tb04210.x","article-title":"The effect of paracetamol or diclofenac administered before operation on postoperative pain and behaviour after adenoidectomy in small children","volume":"47","author":"Baer","year":"1992","journal-title":"Anaesthesia"},{"key":"10.1093\/bja\/88.2.199_bib30","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1034\/j.1399-6576.2000.440312.x","article-title":"Diclofenac or acetaminophen for analgesia in paediatric tonsillectomy outpatients","volume":"44","author":"R\u00f8msing","year":"2000","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1093\/bja\/88.2.199_bib31","first-page":"226","article-title":"A double-blind evaluation of ketorolac tromethamine versus acetaminophen in pediatric tonsillectomy: analgesia and bleeding","volume":"80","author":"Rusy","year":"1995","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/88.2.199_bib32","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/BF03008224","article-title":"Perioperative effects of oral ketorolac and acetaminophen in children undergoing bilateral myringotomy","volume":"39","author":"Watcha","year":"1992","journal-title":"Can J Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib33","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1034\/j.1399-6576.2001.450108.x","article-title":"Preoperative rectal diclofenac versus paracetamol for tonsillectomy: effects on pain and blood loss","volume":"45","author":"Schmidt","year":"2001","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1093\/bja\/88.2.199_bib34","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1002\/j.1552-4604.1989.tb03273.x","article-title":"Ibuprofen and acetaminophen in the relief of acute pain: a randomized, double-blind, placebo-controlled study","volume":"29","author":"Cooper","year":"1989","journal-title":"J Clin Pharmacol"},{"key":"10.1093\/bja\/88.2.199_bib35","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0002-9343(86)90110-5","article-title":"Suppression of dental pain by the preoperative administration of flurbiprofen","volume":"80","author":"Dionne","year":"1986","journal-title":"Am J Med"},{"key":"10.1093\/bja\/88.2.199_bib36","first-page":"394","article-title":"A single-dose, double-blind comparison of naproxen sodium, acetaminophen, and placebo in postoperative dental pain","volume":"16","author":"Kiersch","year":"1994","journal-title":"Clin Ther"},{"key":"10.1093\/bja\/88.2.199_bib37","first-page":"106","article-title":"Analgesics in pediatric dental surgery: relative efficacy of aluminum ibuprofen suspension and acetaminophen elixir","volume":"54","author":"McGaw","year":"1987","journal-title":"ASDC J Dent Child"},{"key":"10.1093\/bja\/88.2.199_bib38","doi-asserted-by":"crossref","first-page":"257","DOI":"10.14219\/jada.archive.1990.0237","article-title":"Multicenter clinical trial of ibuprofen and acetaminophen in the treatment of postoperative dental pain","volume":"121","author":"Mehlisch","year":"1990","journal-title":"J Am Dent Assoc"},{"key":"10.1093\/bja\/88.2.199_bib39","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/0149-2918(95)80063-8","article-title":"Comparative study of ibuprofen lysine and acetaminophen in patients with postoperative dental pain","volume":"17","author":"Mehlisch","year":"1995","journal-title":"Clin Ther"},{"key":"10.1093\/bja\/88.2.199_bib40","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/j.1875-9114.1988.tb04075.x","article-title":"The pain intensity at analgesic intake, and the efficacy of diflunisal in single doses and effervescent acetaminophen in single and repeated doses","volume":"8","author":"Nystrom","year":"1988","journal-title":"Pharmacotherapy"},{"key":"10.1093\/bja\/88.2.199_bib41","first-page":"34","article-title":"The effects of indoprofen vs paracetamol on swelling, pain and other events after surgery","volume":"24","author":"Olstad","year":"1986","journal-title":"Int J Clin Pharmacol Ther Toxicol"},{"key":"10.1093\/bja\/88.2.199_bib42","doi-asserted-by":"crossref","first-page":"11S","DOI":"10.1002\/j.1552-4604.1998.tb04412.x","article-title":"Analgesic efficacy and safety of (R)-ketoprofen in postoperative dental pain","volume":"38","author":"Cooper","year":"1998","journal-title":"J Clin Pharmacol"},{"key":"10.1093\/bja\/88.2.199_bib43","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/sj.bdj.4804728","article-title":"Comparison of diflunisal and paracetamol in the management of pain following wisdom teeth removal","volume":"152","author":"Irvine","year":"1982","journal-title":"Br Dent J"},{"key":"10.1093\/bja\/88.2.199_bib44","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0901-5027(89)80107-9","article-title":"A comparison of paracetamol and diflunisal for pain control following 3rd molar surgery","volume":"18","author":"Rodrigo","year":"1989","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1093\/bja\/88.2.199_bib45","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1046\/j.1365-2125.1996.34015.x","article-title":"The efficacy of ketoprofen and paracetamol (acetaminophen) in postoperative pain after third molar surgery","volume":"41","author":"Seymour","year":"1996","journal-title":"Br J Clin Pharmacol"},{"key":"10.1093\/bja\/88.2.199_bib46","first-page":"229","article-title":"Tenoxicam for pain relief following third molar surgery","volume":"4","author":"Cheung","year":"1992","journal-title":"Anesth Pain Control Dent"},{"key":"10.1093\/bja\/88.2.199_bib47","first-page":"89","article-title":"A controlled comparative evaluation of acetaminophen and aspirin in the treatment of postoperative pain","volume":"7","author":"Mehlisch","year":"1984","journal-title":"Clin Ther"},{"key":"10.1093\/bja\/88.2.199_bib48","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1053\/cp.1999.v66.103629001","article-title":"Combining diclofenac with acetaminophen or acetaminophen-codeine after oral surgery: a randomized, double-blind single-dose study","volume":"66","author":"Breivik","year":"1999","journal-title":"Clin Pharmacol Ther"},{"key":"10.1093\/bja\/88.2.199_bib49","first-page":"573","article-title":"Postextraction pain relief in children: a clinical trial of liquid analgesics","volume":"23","author":"Moore","year":"1985","journal-title":"Int J Clin Pharmacol Ther Toxicol"},{"key":"10.1093\/bja\/88.2.199_bib50","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1177\/030006058401200604","article-title":"A double-blind randomized study of an aspirin\/caffeine combination versus acetaminophen\/aspirin combination versus acetaminophen versus placebo in patients with moderate to severe post-partum pain","volume":"12","author":"Rubin","year":"1984","journal-title":"J Int Med Res"},{"key":"10.1093\/bja\/88.2.199_bib51","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1460-9592.1995.tb00275.x","article-title":"Postoperative morphine requirements, nausea and vomiting following anaesthesia for tonsillectomy. Comparison of intravenous morphine and non-opioid analgesic techniques","volume":"5","author":"Mather","year":"1995","journal-title":"Paediatr Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib52","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1034\/j.1399-6576.2000.440807.x","article-title":"Randomised, placebo-controlled study of the postoperative analgesic effects of ketoprofen after spinal fusion surgery","volume":"44","author":"Aubrun","year":"2000","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1093\/bja\/88.2.199_bib53","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1213\/00000539-200002000-00035","article-title":"The pharmacokinetics and analgesic efficacy of larger dose rectal acetaminophen (40 mg\/kg) in adults: a double-blinded, randomized study","volume":"90","author":"Beck","year":"2000","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/88.2.199_bib54","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/sj.bdj.4805486","article-title":"The efficacy of diclofenac sodium (Voltarol) with and without paracetamol in the control of post-surgical dental pain","volume":"157","author":"Matthews","year":"1984","journal-title":"Br Dent J"},{"key":"10.1093\/bja\/88.2.199_bib55","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1056\/NEJM199906173402407","article-title":"Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs","volume":"340","author":"Wolfe","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1093\/bja\/88.2.199_bib56","doi-asserted-by":"crossref","first-page":"38","DOI":"10.2165\/00003495-199200445-00006","article-title":"Are perioperative nonsteroidal anti-inflammatory drugs ulcerogenic in the short term?","volume":"44","author":"Kehlet","year":"1992","journal-title":"Drugs"},{"key":"10.1093\/bja\/88.2.199_bib57","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1001\/jama.1996.03530290046036","article-title":"Parenteral ketorolac and risk of gastrointestinal and operative site bleeding","volume":"275","author":"Strom","year":"1996","journal-title":"JAMA"},{"key":"10.1093\/bja\/88.2.199_bib58","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0140-6736(91)90744-A","article-title":"Upper gastrointestinal bleeding in relation to previous use of analgesics and non-steroidal anti-inflammatory drugs. Catalan Countries Study on Upper Gastrointestinal Bleeding","volume":"337","author":"Laporte","year":"1991","journal-title":"Lancet"},{"key":"10.1093\/bja\/88.2.199_bib59","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1093\/bja\/71.5.619","article-title":"Aspirin-induced asthma","volume":"71","author":"Power","year":"1993","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib60","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0091-6749(95)70290-3","article-title":"Prevalence of cross-sensitivity with acetaminophen in aspirin-sensitive asthmatic subjects","volume":"96","author":"Settipane","year":"1995","journal-title":"J Allergy Clin Immunol"},{"key":"10.1093\/bja\/88.2.199_bib61","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0140-6736(71)91125-1","article-title":"Plasma-paracetamol half-life and hepatic necrosis in patients with paracetamol overdosage","author":"Prescott","year":"1971","journal-title":"Lancet"},{"key":"10.1093\/bja\/88.2.199_bib62","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.2042-7158.1997.tb06809.x","article-title":"Ibuprofen and paracetamol: relative safety in non-prescription dosages","volume":"49","author":"Rainsford","year":"1997","journal-title":"J Pharm Pharmacol"},{"key":"10.1093\/bja\/88.2.199_bib63","doi-asserted-by":"crossref","first-page":"399","DOI":"10.7326\/0003-4819-104-3-399","article-title":"Acetaminophen hepatotoxicity in alcoholics. A therapeutic misadventure","volume":"104","author":"Seeff","year":"1986","journal-title":"Ann Intern Med"},{"key":"10.1093\/bja\/88.2.199_bib64","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/clpt.1983.14","article-title":"Acetaminophen in chronic liver disease","volume":"33","author":"Benson","year":"1983","journal-title":"Clin Pharmacol Ther"},{"key":"10.1093\/bja\/88.2.199_bib65","doi-asserted-by":"crossref","first-page":"17S","DOI":"10.1016\/S0002-9343(98)00276-9","article-title":"Nonsteroidal anti-inflammatory drug-associated toxicity of the liver, gastrointestinal tract, and esophagus","volume":"105","author":"Bjorkman","year":"1998","journal-title":"Am J Med"},{"key":"10.1093\/bja\/88.2.199_bib66","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1113\/jphysiol.1980.sp013088","article-title":"Prostaglandin synthesis and renal function in man","volume":"298","author":"Haylor","year":"1980","journal-title":"J Physiol (London)"},{"key":"10.1093\/bja\/88.2.199_bib67","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1146\/annurev.pa.33.040193.002251","article-title":"Renal toxicity of nonsteroidal anti-inflammatory drugs","volume":"32","author":"Murray","year":"1993","journal-title":"Ann Rev Pharmacol Toxicol"},{"key":"10.1093\/bja\/88.2.199_bib68","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1177\/0310057X9902700603","article-title":"The effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on postoperative renal function: a meta-analysis","volume":"27","author":"Lee","year":"1999","journal-title":"Anaesth Intensive Care"},{"key":"10.1093\/bja\/88.2.199_bib69","doi-asserted-by":"crossref","first-page":"193","DOI":"10.7326\/0003-4819-126-3-199702010-00003","article-title":"Parenteral ketorolac: The risk of acute renal failure","volume":"126","author":"Feldman","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1093\/bja\/88.2.199_bib70","first-page":"255","article-title":"Acute effects of paracetamol on prostaglandin synthesis and renal function in normal man and in patients with renal failure","volume":"34","author":"Berg","year":"1990","journal-title":"Clin Nephrol"},{"key":"10.1093\/bja\/88.2.199_bib71","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/j.1365-2125.1990.tb03657.x","article-title":"The comparative effects of paracetamol and indomethacin on renal function in healthy female volunteers","volume":"29","author":"Prescott","year":"1990","journal-title":"Br J Clin Pharmacol"},{"key":"10.1093\/bja\/88.2.199_bib72","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1152\/jappl.1999.86.2.598","article-title":"Effects of acetaminophen and ibuprofen on renal function in the stressed kidney","volume":"86","author":"Farquhar","year":"1999","journal-title":"J Appl Physiol"},{"key":"10.1093\/bja\/88.2.199_bib73","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1017\/S0022215100147486","article-title":"Salicylates and post-tonsillectomy haemorrhage","volume":"98","author":"Carrick","year":"1984","journal-title":"J Laryngol Otol"},{"key":"10.1093\/bja\/88.2.199_bib74","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1365-2273.1988.tb01118.x","article-title":"Post-tonsillectomy haemorrhage and analgesics. A comparative study of acetylsalicylic acid and paracetamol","volume":"13","author":"Stage","year":"1988","journal-title":"Clin Otolaryngol"},{"key":"10.1093\/bja\/88.2.199_bib75","first-page":"1136","article-title":"Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine","volume":"81","author":"Gunter","year":"1995","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/88.2.199_bib76","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1007\/BF03011766","article-title":"Preoperative ketorolac increases bleeding after tonsillectomy in children","volume":"43","author":"Splinter","year":"1996","journal-title":"Can J Anaesth"},{"key":"10.1093\/bja\/88.2.199_bib77","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1001\/archotol.1996.01890210017004","article-title":"Intraoperative ketorolac and tonsillectomy bleeding","volume":"122","author":"Judkins","year":"1996","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1093\/bja\/88.2.199_bib78","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1288\/00005537-199506000-00008","article-title":"Perioperative ketorolac tromethamine and postoperative hemorrhage in cases of tonsillectomy and adenoidectomy","volume":"105","author":"Gallagher","year":"1995","journal-title":"Laryngoscope"},{"key":"10.1093\/bja\/88.2.199_bib79","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1080\/000164700317413076","article-title":"A systematic survey of 13 randomized trials of non-steroidal anti-inflammatory drugs for the prevention of heterotopic bone formation after major hip surgery","volume":"71","author":"Neal","year":"2000","journal-title":"Acta Orthop Scand"},{"key":"10.1093\/bja\/88.2.199_bib80","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1302\/0301-620X.82B5.9899","article-title":"Nonunion of the femoral diaphysis. The influence of reaming and non-steroidal anti-inflammatory drugs","volume":"82","author":"Giannoudis","year":"2000","journal-title":"J Bone Joint Surg Br"},{"key":"10.1093\/bja\/88.2.199_bib81","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/0031-9384(94)90388-3","article-title":"Nonsteroidal anti-inflammatory drugs affect normal sleep patterns in humans","volume":"55","author":"Murphy","year":"1994","journal-title":"Physiol Behav"},{"key":"10.1093\/bja\/88.2.199_bib82","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0031-9384(95)02036-5","article-title":"Nonsteroidal anti-inflammatory drugs alter body temperature and suppress melatonin in humans","volume":"59","author":"Murphy","year":"1996","journal-title":"Physiol Behav"},{"key":"10.1093\/bja\/88.2.199_bib83","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1213\/00000539-199905000-00032","article-title":"Persistently high plasma morphine-6-glucuronide levels despite decreased hourly patient-controlled analgesia morphine use after single-dose diclofenac: potential for opioid-related toxicity","volume":"88","author":"Tighe","year":"1999","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/88.2.199_bib84","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/rheumatology\/27.2.117","article-title":"Equianalgesic effects of paracetamol and indomethacin in rheumatoid arthritis","volume":"27","author":"Seideman","year":"1988","journal-title":"Br J Rheumatol"},{"key":"10.1093\/bja\/88.2.199_bib85","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3109\/17453679308993626","article-title":"Naproxen and paracetamol compared with naproxen only in coxarthrosis. Increased effect of the combination in 18 patients","volume":"64","author":"Seideman","year":"1993","journal-title":"Acta Orthop Scand"},{"key":"10.1093\/bja\/88.2.199_bib86","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1093\/rheumatology\/32.12.1077","article-title":"Additive effect of combined naproxen and paracetamol in rheumatoid arthritis","volume":"32","author":"Seideman","year":"1993","journal-title":"Br J Rheumatol"},{"key":"10.1093\/bja\/88.2.199_bib87","first-page":"7","article-title":"Paracetamol in rheumatoid arthritis","volume":"44","author":"Seideman","year":"1993","journal-title":"Agents Actions Suppl"},{"key":"10.1093\/bja\/88.2.199_bib88","series-title":"An Evidence-Based Resource for Pain Relief","first-page":"19","article-title":"Estimating relative effectiveness","author":"McQuay","year":"1998"},{"key":"10.1093\/bja\/88.2.199_bib89","series-title":"An Evidence-Based Resource for Pain Relief","first-page":"14","article-title":"Pain measurement, study design, and validity","author":"McQuay","year":"1998"},{"key":"10.1093\/bja\/88.2.199_bib90","series-title":"An Evidence-Based Resource for Pain Relief","first-page":"32","article-title":"Combining data and interpreting the results","author":"McQuay","year":"1998"},{"key":"10.1093\/bja\/88.2.199_bib91","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1034\/j.1399-6576.2000.440314.x","article-title":"High-dose rectal and oral acetaminophen in postoperative patients-serum and saliva concentrations","volume":"44","author":"Hahn","year":"2000","journal-title":"Acta Anaesthesiol Scand"}],"container-title":["British Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091217365315?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091217365315?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/bja\/article-pdf\/88\/2\/199\/18265627\/880199.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T23:44:35Z","timestamp":1682207075000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007091217365315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,2]]},"references-count":91,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2002,2]]}},"alternative-id":["S0007091217365315"],"URL":"https:\/\/doi.org\/10.1093\/bja\/88.2.199","relation":{},"ISSN":["0007-0912"],"issn-type":[{"value":"0007-0912","type":"print"}],"subject":[],"published":{"date-parts":[[2002,2]]}}}