{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T16:59:51Z","timestamp":1793897991631,"version":"4.8.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,12,4]],"date-time":"2017-12-04T00:00:00Z","timestamp":1512345600000},"content-version":"vor","delay-in-days":1859,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["bjanaesthesia.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["British Journal of Anaesthesia"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1093\/bja\/aes248","type":"journal-article","created":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T23:05:50Z","timestamp":1343862350000},"page":"754-761","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Effect of preoperative fever-range whole-body hyperthermia on immunological markers in patients undergoing colorectal cancer surgery"],"prefix":"10.1016","volume":"109","author":[{"given":"I","family":"Sulyok","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Fleischmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Stift","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Roth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Lebherz-Eichinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Kasper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Spittler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Kimberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/bja\/aes248_bib1","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/archsurg.141.11.1132","article-title":"Cell response to surgery","volume":"141","author":"Ni Choileain","year":"2006","journal-title":"Arch Surg"},{"key":"10.1093\/bja\/aes248_bib2","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s00595-010-4323-z","article-title":"Immunosuppression following surgical and traumatic injury","volume":"40","author":"Kimura","year":"2010","journal-title":"Surg Today"},{"key":"10.1093\/bja\/aes248_bib3","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1213\/01.ANE.0000082995.44040.07","article-title":"Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures","volume":"97","author":"Melamed","year":"2003","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/aes248_bib4","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1093\/bja\/aem218","article-title":"Low-dose ketamine affects immune responses in humans during the early postoperative period","volume":"99","author":"Beilin","year":"2007","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/aes248_bib5","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1097\/00000539-200006000-00028","article-title":"The effects of tramadol and morphine on immune responses and pain after surgery in cancer patients","volume":"90","author":"Sacerdote","year":"2000","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/aes248_bib6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jss.2005.04.028","article-title":"Opiate analgesics contribute to the development of post-injury immunosuppression","volume":"129","author":"Alexander","year":"2005","journal-title":"J Surg Res"},{"key":"10.1093\/bja\/aes248_bib7","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1097\/00000542-200610000-00008","article-title":"Can anesthetic technique for primary breast cancer surgery affect recurrence or metastasis?","volume":"105","author":"Exadaktylos","year":"2006","journal-title":"Anesthesiology"},{"key":"10.1093\/bja\/aes248_bib8","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1093\/bja\/aeq164","article-title":"Effect of anaesthetic technique and other perioperative factors on cancer recurrence","volume":"105","author":"Snyder","year":"2010","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/aes248_bib10","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/01.anes.0000278906.86815.eb","article-title":"Effects of the antimicrobial peptide LL-37 and hyperthermic preconditioning in septic rats","volume":"107","author":"Torossian","year":"2007","journal-title":"Anesthesiology"},{"key":"10.1093\/bja\/aes248_bib11","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1379\/1466-1268(2001)006<0306:CTSVIT>2.0.CO;2","article-title":"Cell type-specific variations in the induction of hsp70 in human leukocytes by feverlike whole body hyperthermia","volume":"6","author":"Oehler","year":"2001","journal-title":"Cell Stress Chaperones"},{"key":"10.1093\/bja\/aes248_bib12","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/02656730801895058","article-title":"The Kadota Fund International Forum 2004\u2014clinical group consensus","volume":"24","author":"van der Zee","year":"2008","journal-title":"Int J Hyperthermia"},{"key":"10.1093\/bja\/aes248_bib13","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/oxfordjournals.bja.a013366","article-title":"Validity and reliability of a postoperative quality of recovery score: the QoR-40","volume":"84","author":"Myles","year":"2000","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/aes248_bib14","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1097\/00000658-200301000-00015","article-title":"Perioperative GLY-GLN infusion diminishes the surgery-induced period of immunosuppression: accelerated restoration of the lipopolysaccharide-stimulated tumor necrosis factor-alpha response","volume":"237","author":"Exner","year":"2003","journal-title":"Ann Surg"},{"key":"10.1093\/bja\/aes248_bib15","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1245\/ASO.2003.02.007","article-title":"Potential prophylactic measures against postoperative immunosuppression: could they reduce recurrence rates in oncological patients?","volume":"10","author":"Shakhar","year":"2003","journal-title":"Ann Surg Oncol"},{"key":"10.1093\/bja\/aes248_bib16","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1067\/msy.2003.141","article-title":"Increased surgical stress promotes tumor metastasis","volume":"133","author":"Tsuchiya","year":"2003","journal-title":"Surgery"},{"key":"10.1093\/bja\/aes248_bib17","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00423-005-0557-4","article-title":"Surgical trauma and immunosuppression: pathophysiology and potential immunomodulatory approaches","volume":"390","author":"Angele","year":"2005","journal-title":"Langenbecks Arch Surg"},{"key":"10.1093\/bja\/aes248_bib18","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1093\/bja\/58.5.535","article-title":"Reversible inhibition of natural killer cell activity by volatile anaesthetic agents in vitro","volume":"58","author":"Woods","year":"1986","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/aes248_bib19","doi-asserted-by":"crossref","first-page":"R645","DOI":"10.1186\/bcr1036","article-title":"Anticancer properties of propofol-docosahexaenoate and propofol-eicosapentaenoate on breast cancer cells","volume":"7","author":"Siddiqui","year":"2005","journal-title":"Breast Cancer Res"},{"key":"10.1093\/bja\/aes248_bib20","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1056\/NEJM199605093341901","article-title":"Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group","volume":"334","author":"Kurz","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1093\/bja\/aes248_bib21","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1097\/00000542-199909000-00026","article-title":"Hypothermia in barbiturate-anesthetized rats suppresses natural killer cell activity and compromises resistance to tumor metastasis: a role for adrenergic mechanisms","volume":"91","author":"Ben-Eliyahu","year":"1999","journal-title":"Anesthesiology"},{"key":"10.1093\/bja\/aes248_bib22","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s12026-009-8115-8","article-title":"Diverse immune mechanisms may contribute to the survival benefit seen in cancer patients receiving hyperthermia","volume":"46","author":"Peer","year":"2010","journal-title":"Immunol Res"},{"key":"10.1093\/bja\/aes248_bib23","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0140-6736(03)14075-5","article-title":"Heat shock proteins as regulators of the immune response","volume":"362","author":"Pockley","year":"2003","journal-title":"Lancet"},{"key":"10.1093\/bja\/aes248_bib24","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1097\/00002371-199311000-00016","article-title":"Heat shock protein vaccines against cancer","volume":"14","author":"Blachere","year":"1993","journal-title":"J Immunother Emphasis Tumor Immunol"},{"key":"10.1093\/bja\/aes248_bib25","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00262-002-0263-9","article-title":"Immunization with heat shock protein 70 from methylcholanthrene-induced sarcomas induces tumor protection correlating with in vitro T cell responses","volume":"51","author":"Ciupitu","year":"2002","journal-title":"Cancer Immunol Immunother"},{"key":"10.1093\/bja\/aes248_bib26","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1158\/0008-5472.CAN-07-5704","article-title":"Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis","volume":"68","author":"Egberts","year":"2008","journal-title":"Cancer Res"},{"issue":"Suppl. 1","key":"10.1093\/bja\/aes248_bib27","doi-asserted-by":"crossref","first-page":"i104","DOI":"10.1136\/ard.2010.140145","article-title":"Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage","volume":"70","author":"Grivennikov","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"10.1093\/bja\/aes248_bib28","doi-asserted-by":"crossref","first-page":"C1140","DOI":"10.1152\/ajpcell.1995.269.5.C1140","article-title":"Warming macrophages to febrile range destabilizes tumor necrosis factor-alpha mRNA without inducing heat shock","volume":"269","author":"Ensor","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1093\/bja\/aes248_bib29","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0009-8981(02)00101-8","article-title":"Pathobiochemistry and clinical use of procalcitonin","volume":"323","author":"Meisner","year":"2002","journal-title":"Clin Chim Acta"},{"key":"10.1093\/bja\/aes248_bib30","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1213\/01.ane.0000215998.21739.48","article-title":"Increased interleukin-6 after cardiac surgery predicts infection","volume":"102","author":"Sander","year":"2006","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/aes248_bib31","first-page":"283","article-title":"The use of rectal temperature to monitor heat stroke","volume":"89","author":"Ash","year":"1992","journal-title":"Mo Med"}],"container-title":["British Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091217316379?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091217316379?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/bja\/article-pdf\/109\/5\/754\/18254809\/aes248.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T18:35:26Z","timestamp":1757788526000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007091217316379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0007091217316379"],"URL":"https:\/\/doi.org\/10.1093\/bja\/aes248","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717954660.793463274","asserted-by":"object"}]},"ISSN":["0007-0912"],"issn-type":[{"value":"0007-0912","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of preoperative fever-range whole-body hyperthermia on immunological markers in patients undergoing colorectal cancer surgery","name":"articletitle","label":"Article Title"},{"value":"British Journal of Anaesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/bja\/aes248","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 The Author(s). Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}