{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T10:55:04Z","timestamp":1792580104606,"version":"4.5.0"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,12,4]],"date-time":"2017-12-04T00:00:00Z","timestamp":1512345600000},"content-version":"vor","delay-in-days":703,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Anaesthesia"],"published-print":{"date-parts":[[2016]]},"DOI":"10.1093\/bja\/aew214","type":"journal-article","created":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T11:29:28Z","timestamp":1472210968000},"page":"ii74-ii84","source":"Crossref","is-referenced-by-count":57,"special_numbering":"S2","title":["New antiplatelet drugs and new oral anticoagulants"],"prefix":"10.1016","volume":"117","author":[{"given":"V.","family":"Koenig-Oberhuber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Filipovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/bja\/aew214_bib1","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1016\/S0140-6736(14)61652-4","article-title":"On World Thrombosis Day","volume":"384","author":"Raskob","year":"2014","journal-title":"Lancet"},{"key":"10.1093\/bja\/aew214_bib2","series-title":"Deaths from cardiovascular diseases and diabetes. WHO","year":"2016"},{"key":"10.1093\/bja\/aew214_bib3","doi-asserted-by":"crossref","first-page":"2922","DOI":"10.1093\/eurheartj\/ehr373","article-title":"Antiplatelet agents for the treatment and prevention of atherothrombosis","volume":"32","author":"Patrono","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1093\/bja\/aew214_bib4","unstructured":"Choudhry NK, Desai NR, Fischer MA et al. 2012. Alosa Foundation, Inc. Available from http:\/\/www.alosafoundation.org\/wp-content\/uploads\/2013\/03\/Antiplatelet_UnAd.pdf (accessed 21 February 2016)."},{"key":"10.1093\/bja\/aew214_bib5","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1093\/eurheartj\/ehu278","volume":"35","author":"Windecker","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1093\/bja\/aew214_bib6","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1161\/STR.0000000000000024","article-title":"Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"45","author":"Kernan","year":"2014","journal-title":"Stroke"},{"key":"10.1093\/bja\/aew214_bib7","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1161\/CIRCULATIONAHA.110.963843","article-title":"Aspirin: a historical and contemporary therapeutic overview","volume":"123","author":"Fuster","year":"2011","journal-title":"Circulation"},{"issue":"Suppl 1","key":"10.1093\/bja\/aew214_bib8","doi-asserted-by":"crossref","first-page":"i3","DOI":"10.1093\/bja\/aet402","article-title":"Perioperative management of antiplatelet therapy","volume":"111","author":"Oprea","year":"2013","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/aew214_bib9","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1213\/ANE.0b013e318203f38d","article-title":"Antiplatelet drugs: a review of their pharmacology and management in the perioperative period","volume":"112","author":"Hall","year":"2011","journal-title":"Anesth Analg"},{"key":"10.1093\/bja\/aew214_bib10","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.324.7329.71","article-title":"Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients","volume":"324","year":"2002","journal-title":"Br Med J"},{"key":"10.1093\/bja\/aew214_bib11","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/j.athoracsur.2012.07.086","article-title":"2012 update to the Society of Thoracic Surgeons guideline on use of antiplatelet drugs in patients having cardiac and noncardiac operations","volume":"94","author":"Ferraris","year":"2012","journal-title":"Ann Thorac Surg"},{"key":"10.1093\/bja\/aew214_bib12","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1182\/asheducation-2011.1.62","article-title":"Advances in antiplatelet therapy","volume":"2011","author":"Michelson","year":"2011","journal-title":"Hematology Am Soc Hematol Educ Program"},{"issue":"2 Suppl","key":"10.1093\/bja\/aew214_bib13","doi-asserted-by":"crossref","first-page":"e120S","DOI":"10.1378\/chest.11-2294","article-title":"New antithrombotic drugs: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"141","author":"Weitz","year":"2012","journal-title":"Chest"},{"key":"10.1093\/bja\/aew214_bib14","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0140-6736(98)11086-3","article-title":"Platelet GPIIb-IIIa blockers","volume":"353","author":"Topol","year":"1999","journal-title":"Lancet"},{"key":"10.1093\/bja\/aew214_bib15","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/j.1365-2125.2011.03999.x","article-title":"Anti-platelet therapy: ADP receptor antagonists","volume":"72","author":"Wijeyeratne","year":"2011","journal-title":"Br J Clin Pharmacol"},{"issue":"Suppl 2","key":"10.1093\/bja\/aew214_bib16","first-page":"29","article-title":"Pharmacokinetic profile of 14C-labeled clopidogrel","volume":"25","author":"Lins","year":"1999","journal-title":"Semin Thromb Hemost"},{"key":"10.1093\/bja\/aew214_bib17","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1517\/14656566.2010.498820","article-title":"Nonresponders to clopidogrel: pharmacokinetics and interactions involved","volume":"11","author":"Giorgi","year":"2010","journal-title":"Expert Opin Pharmacother"},{"key":"10.1093\/bja\/aew214_bib18","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1002\/phar.1477","article-title":"Ticagrelor: pharmacokinetics, pharmacodynamics, clinical efficacy, and safety","volume":"34","author":"Dobesh","year":"2014","journal-title":"Pharmacotherapy"},{"key":"10.1093\/bja\/aew214_bib19","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1182\/asheducation.V2012.1.529.3799663","article-title":"Perioperative management of patients on chronic antithrombotic therapy","volume":"2012","author":"Ortel","year":"2012","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"10.1093\/bja\/aew214_bib20","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1001\/jama.2011.2002","article-title":"Bridging antiplatelet therapy with cangrelor in patients undergoing cardiac surgery: a randomized controlled trial","volume":"307","author":"Angiolillo","year":"2012","journal-title":"JAMA"},{"key":"10.1093\/bja\/aew214_bib21","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ehj.2003.10.013","article-title":"Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology","volume":"25","author":"Patrono","year":"2004","journal-title":"Eur Heart J"},{"key":"10.1093\/bja\/aew214_bib22","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1160\/TH11-10-0727","article-title":"GPIIb\/IIIa inhibitors: from bench to bedside and back to bench again","volume":"107","author":"Armstrong","year":"2012","journal-title":"Thromb Haemost"},{"key":"10.1093\/bja\/aew214_bib23","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/j.1365-2125.2010.03879.x","article-title":"Anti-platelet therapy: glycoprotein IIb-IIIa antagonists","volume":"72","author":"Schneider","year":"2011","journal-title":"Br J Clin Pharmacol"},{"key":"10.1093\/bja\/aew214_bib24","series-title":"Thromboseprophylaxe und periinterventionelle antithrombotische Therapie","author":"Filipovic","year":"2014"},{"key":"10.1093\/bja\/aew214_bib25","doi-asserted-by":"crossref","first-page":"e326S","DOI":"10.1378\/chest.11-2298","article-title":"Perioperative management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice guidelines (9th edition)","volume":"141","author":"Douketis","year":"2012","journal-title":"Chest"},{"key":"10.1093\/bja\/aew214_bib26","first-page":"1484","article-title":"Perioperative antiplatelet therapy","volume":"82","author":"Chassot","year":"2010","journal-title":"Am Fam Physician"},{"issue":"Suppl 1","key":"10.1093\/bja\/aew214_bib27","doi-asserted-by":"crossref","first-page":"i96","DOI":"10.1093\/bja\/aet401","article-title":"New oral anticoagulants and regional anaesthesia","volume":"111","author":"Benzon","year":"2013","journal-title":"Br J Anaesth"},{"key":"10.1093\/bja\/aew214_bib28","series-title":"Guidelines for the use of antiplatelet therapy in patients with coronary stents undergoing non-cardiac surgery","year":"2009"},{"key":"10.1093\/bja\/aew214_bib29","series-title":"Empfehlungen der Arbeitsgruppe perioperative Gerinnung der O\u00d6GARI","year":"2013"},{"key":"10.1093\/bja\/aew214_bib30","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1253\/circj.CJ-88-0009","article-title":"Guidelines for Perioperative Cardiovascular Evaluation and Management for Noncardiac Surgery","volume":"75","author":"Kyo","year":"2011","journal-title":"Circ J"},{"key":"10.1093\/bja\/aew214_bib31","series-title":"Perioperative Management of Antithrombotic Therapy","author":"Douketis","year":"2016"},{"key":"10.1093\/bja\/aew214_bib32","doi-asserted-by":"crossref","first-page":"38","DOI":"10.4244\/EIJV10I1A8","article-title":"Perioperative management of antiplatelet therapy in patients with coronary stents undergoing cardiac and non-cardiac surgery: a consensus document from Italian cardiological, surgical and anaesthesiological societies","volume":"10","author":"Rossini","year":"2014","journal-title":"EuroIntervention"},{"key":"10.1093\/bja\/aew214_bib33","doi-asserted-by":"crossref","first-page":"49","DOI":"10.7326\/0003-4819-157-1-201206190-00429","article-title":"Red blood cell transfusion: a clinical practice guideline from the AABB","volume":"157","author":"Carson","year":"2012","journal-title":"Ann Intern Med"},{"key":"10.1093\/bja\/aew214_bib34","first-page":"349","article-title":"Antiplatelet agents in clinical practice and their haemorrhagic risk","volume":"11","author":"Gresele","year":"2013","journal-title":"Blood Transfus"},{"key":"10.1093\/bja\/aew214_bib35","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1007\/s00108-009-2569-6","article-title":"Significance of platelet function tests","volume":"51","author":"Wolf","year":"2010","journal-title":"Internist"},{"key":"10.1093\/bja\/aew214_bib36","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/j.1365-2125.2011.03955.x","article-title":"Monitoring the effectiveness of antiplatelet therapy: opportunities and limitations","volume":"72","author":"Sambu","year":"2011","journal-title":"Br J Clin Pharmacol"},{"key":"10.1093\/bja\/aew214_bib37","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s00101-012-2041-1","article-title":"Platelet function: new drugs, new assays: possible impacts on operative medicine?","volume":"61","author":"Mahla","year":"2012","journal-title":"Anaesthesist"},{"key":"10.1093\/bja\/aew214_bib38","doi-asserted-by":"crossref","first-page":"e120S","DOI":"10.1378\/chest.11-2294","article-title":"American College of Chest Physicians. New antithrombotic drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines","volume":"141(2 Suppl","author":"Weitz","year":"2012","journal-title":"Chest"},{"key":"10.1093\/bja\/aew214_bib39","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1161\/CIRCULATIONAHA.109.853119","article-title":"New anticoagulants","volume":"121","author":"Eikelboom","year":"2010","journal-title":"Circulation"},{"key":"10.1093\/bja\/aew214_bib40","doi-asserted-by":"crossref","first-page":"e24S","DOI":"10.1378\/chest.11-2291","article-title":"Parenteral anticoagulants: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"141","author":"Garcia","year":"2012","journal-title":"Chest"},{"key":"10.1093\/bja\/aew214_bib41","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1365-2125.2011.03916.x","article-title":"Parenteral anticoagulants: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"72","author":"Lee","year":"2011","journal-title":"Br J Clin Pharmacol"},{"key":"10.1093\/bja\/aew214_bib42","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s40262-012-0030-9","article-title":"New oral anticoagulants: comparative pharmacology with vitamin K antagonists","volume":"52","author":"Scaglione","year":"2013","journal-title":"Clin Pharmacokinet"},{"issue":"6 Suppl","key":"10.1093\/bja\/aew214_bib43","doi-asserted-by":"crossref","first-page":"160S","DOI":"10.1378\/chest.08-0670","article-title":"Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)","volume":"133","author":"Ansell","year":"2008","journal-title":"Chest"},{"key":"10.1093\/bja\/aew214_bib44","unstructured":"2005. Available from http:\/\/www.drugbank.ca\/drugs\/DB00682 (accessed 25 October 2015))."},{"key":"10.1093\/bja\/aew214_bib45","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1182\/asheducation-2013.1.464","article-title":"Pros and cons of new oral anticoagulants","volume":"2013","author":"Bauer","year":"2013","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"10.1093\/bja\/aew214_bib46","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/978-3-642-00663-0_13","article-title":"Drug-induced liver injury in humans: the case of ximelagatran","volume":"196","author":"Keisu","year":"2010","journal-title":"Handb Exp Pharmacol"},{"key":"10.1093\/bja\/aew214_bib47","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1161\/CIRCULATIONAHA.110.004424","article-title":"Dabigatran etexilate: a new oral thrombin inhibitor","volume":"123","author":"Hankey","year":"2011","journal-title":"Circulation"},{"key":"10.1093\/bja\/aew214_bib48","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1053\/j.seminhematol.2014.03.005","article-title":"Direct oral anticoagulants\u2014pharmacology, drug interactions, and side effects","volume":"51","author":"Dempfle","year":"2014","journal-title":"Semin Hematol"},{"key":"10.1093\/bja\/aew214_bib49","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.2146\/ajhp110418","article-title":"Apixaban: a novel oral inhibitor of factor Xa","volume":"69","author":"Nutescu","year":"2012","journal-title":"Am J Health Syst Pharm"},{"key":"10.1093\/bja\/aew214_bib50","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.2146\/ajhp070624","article-title":"Rivaroxaban: an oral direct inhibitor of factor Xa","volume":"65","author":"Gulseth","year":"2008","journal-title":"Am J Health Syst Pharm"},{"key":"10.1093\/bja\/aew214_bib51","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1093\/eurheartj\/ehu181","article-title":"Edoxaban: a focused review of its clinical pharmacology","volume":"35","author":"Lip","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1093\/bja\/aew214_bib52","series-title":"Anticoagulant Management of Patients Undergoing Elective who Require Temporary Interruption of Warfarin Therapy","author":"Douketis","year":"2005"},{"key":"10.1093\/bja\/aew214_bib53","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1056\/NEJMoa1501035","article-title":"Perioperative bridging anticoagulation in patients with atrial fibrillation","volume":"373","author":"Douketis","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1093\/bja\/aew214_bib54","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1161\/CIRCULATIONAHA.114.011777","article-title":"Use and outcomes associated with bridging during anticoagulation interruptions in patients with atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)","volume":"131","author":"Steinberg","year":"2015","journal-title":"Circulation"},{"key":"10.1093\/bja\/aew214_bib55","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1161\/CIR.0000000000000040","article-title":"2014 AHA\/ACC\/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology\/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society","volume":"130","author":"January","year":"2014","journal-title":"Circulation"},{"key":"10.1093\/bja\/aew214_bib56","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1016\/j.jacc.2015.08.002","article-title":"Bridging anticoagulation: primum non nocere","volume":"66","author":"Rechenmacher","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1093\/bja\/aew214_bib57","unstructured":"CoaguSave 2015. Available from http:\/\/www.girard.li\/girardDev\/index_light_slider.html (accessed 25 October 2015)."},{"key":"10.1093\/bja\/aew214_bib58","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1093\/eurheartj\/eht557","article-title":"Peri-interventional management of novel oral anticoagulants in daily care: results from the prospective Dresden NOAC registry","volume":"35","author":"Beyer-Westendorf","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1093\/bja\/aew214_bib59","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1056\/NEJMra1206531","article-title":"Management of antithrombotic therapy in patients undergoing invasive procedures","volume":"368","author":"Baron","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1093\/bja\/aew214_bib60","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1053\/j.seminhematol.2014.02.001","article-title":"Perioperative management issues of direct oral anticoagulants","volume":"51","author":"Kozek-Langenecker","year":"2014","journal-title":"Semin Hematol"},{"key":"10.1093\/bja\/aew214_bib61","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1053\/j.seminhematol.2014.02.002","article-title":"Direct oral anticoagulants and bleeding risk (in comparison to vitamin K antagonists and heparins), and the treatment of bleeding","volume":"51","author":"Palareti","year":"2014","journal-title":"Semin Hematol"},{"key":"10.1093\/bja\/aew214_bib62","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1586\/14779072.2015.987126","article-title":"Monitoring and reversal strategies for new oral anticoagulants","volume":"13","author":"Vanden Daelen","year":"2015","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1093\/bja\/aew214_bib63","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s11239-013-0885-0","article-title":"Reversal of novel oral anticoagulants in patients with major bleeding","volume":"35","author":"Siegal","year":"2013","journal-title":"J Thromb Thrombolysis"},{"key":"10.1093\/bja\/aew214_bib64","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/imj.12448","article-title":"New oral anticoagulants: a practical guide on prescription, laboratory testing and peri-procedural\/bleeding management. Australasian Society of Thrombosis and Haemostasis","volume":"44","author":"Tran","year":"2014","journal-title":"Intern Med J"},{"key":"10.1093\/bja\/aew214_bib65","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.amjmed.2011.10.017","article-title":"Interpretation of point-of-care INR results in patients treated with dabigatran","volume":"125","author":"van Ryn","year":"2012","journal-title":"Am J Med"},{"key":"10.1093\/bja\/aew214_bib66","series-title":"New\/Novel Oral Anticoagulants (NOACs) Perioperative Management","year":"2015"},{"key":"10.1093\/bja\/aew214_bib67","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1093\/eurheartj\/eht134","article-title":"EHRA practical guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation: executive summary","volume":"34","author":"Heidbuchel","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1093\/bja\/aew214_bib68","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1477-9560-11-8","article-title":"New oral anticoagulants: discussion on monitoring and adherence should start now!","volume":"11","author":"Ten Cate","year":"2013","journal-title":"Thromb J"},{"key":"10.1093\/bja\/aew214_bib69","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1093\/eurheartj\/eht049","article-title":"New oral anticoagulants in addition to single or dual antiplatelet therapy after an acute coronary syndrome: a systematic review and meta-analysis","volume":"34","author":"Oldgren","year":"2013","journal-title":"Eur Heart J"}],"container-title":["British Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091217301472?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091217301472?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/bja\/article-pdf\/117\/suppl_2\/ii74\/6692055\/aew214.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T15:13:26Z","timestamp":1601046806000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007091217301472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":69,"alternative-id":["S0007091217301472"],"URL":"https:\/\/doi.org\/10.1093\/bja\/aew214","relation":{},"ISSN":["0007-0912"],"issn-type":[{"value":"0007-0912","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}