{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T22:20:25Z","timestamp":1786659625004,"version":"build-2736575974"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T00:00:00Z","timestamp":1686614400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Clinical Research Plan of Shanghai Hospital Development Center","award":["SHDC2020CR1014B"],"award-info":[{"award-number":["SHDC2020CR1014B"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81972934"],"award-info":[{"award-number":["81972934"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273515"],"award-info":[{"award-number":["82273515"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003395","name":"Shanghai Municipal Education Commission","doi-asserted-by":"publisher","award":["2019-01-07-00-07-E00046"],"award-info":[{"award-number":["2019-01-07-00-07-E00046"]}],"id":[{"id":"10.13039\/501100003395","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Shanghai Academic Research Leader","doi-asserted-by":"publisher","award":["20XD1403300"],"award-info":[{"award-number":["20XD1403300"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Patient global assessment (PtGA) has been recommended as one of the core domains in psoriasis clinical trials. Among multiple versions of PtGA, the single-question, 11-point PtGA numeric rating scale (NRS) remains to be validated in patients with plaque psoriasis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To evaluate the psychometric characteristics of an 11-point PtGA NRS for disease severity in patients with moderate-to-severe plaque psoriasis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Data were analysed from 759 patients with moderate-to-severe psoriasis in the Shanghai Psoriasis Effectiveness Evaluation CoHort (SPEECH), a prospective, multicentre and observational registry assessing the comparative effectiveness and safety of biologics (adalimumab, ustekinumab, secukinumab or ixekizumab), conventional systemic therapies (acitretin or methotrexate) and phototherapy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The test\u2013retest reliability of the PtGA NRS showed good agreement (intraclass correlation coefficient range 0.79\u20130.83). No floor or ceiling effects of PtGA NRS were observed. The PtGA NRS was significantly correlated with the Psoriasis Area and Severity Index (PASI), static Physician Global Assessment (sPGA), body surface area, Dermatology Quality of Life Index (DLQI) and Hospital Anxiety and Depression Scale. Relatively large correlations of PtGA NRS with PASI and the DLQI \u2018symptoms and feelings\u2019 domain (all correlations \u2265 0.4 except at baseline) supported convergent validity. The presence of psoriatic arthritis or joint symptoms had no significant association with the PtGA NRS. In multivariate regression analyses, the PtGA NRS at baseline was predicted by age, lesion extent, lesion intensity, patients\u2019 symptoms and feelings, and impact on work or school. The PtGA NRS displayed known-groups validity with the PASI, sPGA and DLQI score bands. The PtGA NRS was responsive to change in PASI and DLQI after treatment. Anchor- and distribution-based approaches supported \u20133 as the minimal important difference for PtGA NRS. An absolute PtGA NRS \u2264 2 during follow-up was concordant with the state of minimal disease activity based on a 90% reduction in PASI (PASI 90) or PASI 90 plus a DLQI of 0\/1. Sensitivity analysis using subgroup comparison and multiple imputation model yielded consistent conclusions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The PtGA NRS showed good reliability, validity and responsiveness in patients with psoriasis, and was feasible in clinical trials and daily practice.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjd\/ljad188","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T12:30:08Z","timestamp":1686573008000},"page":"437-446","source":"Crossref","is-referenced-by-count":22,"title":["Measurement properties of the patient global assessment numerical rating scale in moderate-to-severe psoriasis"],"prefix":"10.1093","volume":"189","author":[{"given":"Ning","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Dermatology, Shanghai Skin Disease Hospital, Institute of Psoriasis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Shanghai Skin Disease Hospital, Institute of Psoriasis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Shanghai Skin Disease Hospital, Institute of Psoriasis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Shanghai Tenth People\u2019s Hospital, Tongji University School of Medicine , Shanghai , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhua","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Huashan Hospital, Fudan University , Shanghai , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinling","family":"Bi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Changhai Hospital, Second Military Medical University , Shanghai , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital , Shanghai , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine , Shanghai , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangfeng","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Shanghai Skin Disease Hospital, Institute of Psoriasis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1273-7881","authenticated-orcid":false,"given":"Yuling","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Shanghai Skin Disease Hospital, Institute of Psoriasis"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,6,13]]},"reference":[{"key":"2023091515310710300_ljad188-B1","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","article-title":"Psoriasis","volume":"397","author":"Griffiths","year":"2021","journal-title":"Lancet"},{"key":"2023091515310710300_ljad188-B2","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1001\/jamadermatol.2021.3341","article-title":"Patient-reported outcome measures as complementary information to clinician-reported outcome \u00admeasures in patients with psoriasis","volume":"157","author":"Barbieri","year":"2021","journal-title":"JAMA Dermatol"},{"key":"2023091515310710300_ljad188-B3","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s40257-019-00496-w","article-title":"Investigator and patient global assessment measures for psoriasis clinical trials: a systematic review on measurement properties from the International Dermatology Outcome Measures (IDEOM) initiative","volume":"21","author":"Perez-Chada","year":"2020","journal-title":"Am J Clin Dermatol"},{"key":"2023091515310710300_ljad188-B4","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.jaad.2019.09.008","article-title":"Achieving consensus on patient-reported outcome measures in clinical practice for inflammatory skin disorders","volume":"88","author":"Perez-Chada","year":"2023","journal-title":"J Am Acad Dermatol"},{"key":"2023091515310710300_ljad188-B5","doi-asserted-by":"crossref","first-page":"898","DOI":"10.3899\/jrheum.100857","article-title":"Patient global assessment in psoriatic arthritis: a multicenter GRAPPA and OMERACT study","volume":"38","author":"Cauli","year":"2011","journal-title":"J Rheumatol"},{"key":"2023091515310710300_ljad188-B6","doi-asserted-by":"crossref","first-page":"844","DOI":"10.3899\/jrheum.110919","article-title":"Construct validity of the modified numeric rating scale of patient global assessment in psoriatic arthritis","volume":"39","author":"Leung","year":"2012","journal-title":"J Rheumatol"},{"key":"2023091515310710300_ljad188-B7","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.jbspin.2015.06.018","article-title":"Patient global assessment in psoriatic arthritis \u2013 what does it mean? An analysis of 223 patients from the Psoriatic arthritis impact of disease (PsAID) study","volume":"83","author":"T\u00e4lli","year":"2016","journal-title":"Joint Bone Spine"},{"key":"2023091515310710300_ljad188-B8","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1136\/ard.2006.051706","article-title":"Performance of response criteria for assessing peripheral arthritis in patients with psoriatic arthritis: analysis of data from randomised controlled trials of two tumour necrosis factor inhibitors","volume":"65","author":"Fransen","year":"2006","journal-title":"Ann Rheum Dis"},{"key":"2023091515310710300_ljad188-B9","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1002\/acr.20155","article-title":"Validation of minimal disease activity criteria for psoriatic arthritis using interventional trial data","volume":"62","author":"Coates","year":"2010","journal-title":"Arthritis Care Res (Hoboken"},{"key":"2023091515310710300_ljad188-B10","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1001\/jamadermatol.2018.1165","article-title":"Identifying a core domain set to assess psoriasis in clinical trials","volume":"154","author":"Callis Duffin","year":"2018","journal-title":"JAMA Dermatol"},{"key":"2023091515310710300_ljad188-B11","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1038\/jid.2009.391","article-title":"How good are clinical severity and outcome measures for psoriasis?: quantitative evaluation in a systematic review","volume":"130","author":"Spuls","year":"2010","journal-title":"J Invest Dermatol"},{"key":"2023091515310710300_ljad188-B12","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.jpainsymman.2010.08.016","article-title":"Studies comparing Numerical Rating Scales, Verbal Rating Scales, and Visual Analogue Scales for assessment of pain intensity in adults: a systematic literature review","volume":"41","author":"Hjermstad","year":"2011","journal-title":"J Pain Symptom Manage"},{"key":"2023091515310710300_ljad188-B13","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1111\/j.1365-2133.2007.07817.x","article-title":"The Dermatology Life Quality Index: assessing the efficacy of biological therapies for psoriasis","volume":"156","author":"Katugampola","year":"2007","journal-title":"Br J Dermatol"},{"issue":"29","key":"2023091515310710300_ljad188-B14","article-title":"The hospital anxiety and depression scale","volume":"1","author":"Snaith","year":"2003","journal-title":"Health Qual Life Outcomes"},{"key":"2023091515310710300_ljad188-B15","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jcm.2016.02.012","article-title":"A guideline of selecting and reporting intraclass correlation coefficients for reliability research","volume":"15","author":"Koo","year":"2016","journal-title":"J Chiropr Med"},{"key":"2023091515310710300_ljad188-B16","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jclinepi.2006.03.012","article-title":"Quality criteria were proposed for measurement properties of health status questionnaires","volume":"60","author":"Terwee","year":"2007","journal-title":"J Clin Epidemiol"},{"key":"2023091515310710300_ljad188-B17","volume-title":"Psychological Testing and Assessment.","author":"Cohen","year":"2017","edition":"9th edn"},{"key":"2023091515310710300_ljad188-B18","volume-title":"Applied Multivariate Statistics for the Social Sciences","author":"Stevens","year":"2002"},{"key":"2023091515310710300_ljad188-B19","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1111\/bjd.20600","article-title":"MULTIPLE ways to correct for MULTIPLE comparisons in MULTIPLE types of studies","volume":"185","author":"Hollestein","year":"2021","journal-title":"Br J Dermatol"},{"key":"2023091515310710300_ljad188-B20","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.5334\/ijic.65","article-title":"Statistical significant change versus relevant or important change in (quasi) experimental design: some conceptual and methodological problems in estimating magnitude of intervention-related change in health services research","volume":"2","author":"Middel","year":"2002","journal-title":"Int J Integr Care"},{"key":"2023091515310710300_ljad188-B21","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jclinepi.2017.06.009","article-title":"Minimal important difference to infer changes in health-related quality of life \u2013 a systematic review","volume":"89","author":"Jayadevappa","year":"2017","journal-title":"J Clin Epidemiol"},{"key":"2023091515310710300_ljad188-B22","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1159\/000365390","article-title":"Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data","volume":"230","author":"Basra","year":"2015","journal-title":"Dermatology"},{"key":"2023091515310710300_ljad188-B23","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3","article-title":"Index for rating diagnostic tests","volume":"3","author":"Youden","year":"1950","journal-title":"Cancer"},{"key":"2023091515310710300_ljad188-B24","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/s12955-020-01344-w","article-title":"How is the minimal clinically important difference established in health-related quality of life instruments? Review of anchors and methods","volume":"18","author":"Mouelhi","year":"2020","journal-title":"Health Qual Life Outcomes"},{"key":"2023091515310710300_ljad188-B25","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.jaad.2017.06.162","article-title":"Assessing clinical response and defining minimal disease activity in plaque psoriasis with the Physician Global Assessment and body surface area (PGA \u00d7 BSA) composite tool: an analysis of apremilast phase 3 ESTEEM data","volume":"77","author":"Gottlieb","year":"2017","journal-title":"J Am Acad Dermatol"},{"key":"2023091515310710300_ljad188-B26","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1038\/jid.2013.138","article-title":"The Simplified Psoriasis Index (SPI): a practical tool for assessing psoriasis","volume":"133","author":"Chularojanamontri","year":"2013","journal-title":"J Invest Dermatol"},{"key":"2023091515310710300_ljad188-B27","first-page":"419","article-title":"Factor analysis of the Beer Sheva Psoriasis Severity Score (BPSS)","volume":"10","author":"Cohen","year":"2008","journal-title":"Isr Med Assoc J"},{"key":"2023091515310710300_ljad188-B28","first-page":"260","article-title":"The National Psoriasis Foundation Psoriasis Score (NPF-PS) system versus the Psoriasis Area Severity Index (PASI) and Physician's Global Assessment (PGA): a comparison","volume":"2","author":"Gottlieb","year":"2003","journal-title":"J Drugs Dermatol"},{"key":"2023091515310710300_ljad188-B29","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.3899\/jrheum.090084","article-title":"Test-retest reliability of patient global assessment and physician global assessment in rheumatoid arthritis","volume":"36","author":"Rohekar","year":"2009","journal-title":"J\u00a0Rheumatol"},{"key":"2023091515310710300_ljad188-B30","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.jaad.2021.01.014","article-title":"Assessing psoriasis severity: psychometric validation of overall physician global assessment","volume":"86","author":"Taliercio","year":"2022","journal-title":"J Am Acad Dermatol"},{"key":"2023091515310710300_ljad188-B31","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s12895-019-0088-2","article-title":"A multi-item Physician Global Assessment scale to assess psoriasis disease severity: validation based on four phase III tofacitinib studies","volume":"19","author":"Callis Duffin","year":"2019","journal-title":"BMC Dermatol"},{"key":"2023091515310710300_ljad188-B32","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1007\/s11136-013-0384-y","article-title":"Psychometric validation of the physician global assessment scale for assessing severity of psoriasis disease activity","volume":"22","author":"Cappelleri","year":"2013","journal-title":"Qual Life Res"},{"key":"2023091515310710300_ljad188-B33","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3200\/JEXE.74.3.249-266","article-title":"Understanding correlation: factors that affect the size of r","volume":"74","author":"Goodwin","year":"2006","journal-title":"J Exp Educ"},{"key":"2023091515310710300_ljad188-B34","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s13555-020-00475-8","article-title":"Treat-to-target approach for the management of patients with moderate-to-severe plaque psoriasis: consensus recommendations","volume":"11","author":"Gisondi","year":"2021","journal-title":"Dermatol Ther (Heidelb)"},{"key":"2023091515310710300_ljad188-B35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00403-010-1080-1","article-title":"Definition of treatment goals for moderate to severe psoriasis: a European consensus","volume":"303","author":"Mrowietz","year":"2011","journal-title":"Arch Dermatol Res"},{"key":"2023091515310710300_ljad188-B36","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1111\/bjd.18333","article-title":"Psoriasis treat to target: defining outcomes in psoriasis using data from a real-world, population-based cohort study (the British Association of Dermatologists Biologics and Immunomodulators Register, BADBIR)","volume":"182","author":"Mahil","year":"2020","journal-title":"Br J Dermatol"},{"key":"2023091515310710300_ljad188-B37","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1159\/000499925","article-title":"Exploration of the product of the 5-Point Investigator's Global Assessment and body surface area (IGA \u00d7 BSA) as a practical minimal disease activity goal in patients with moderate-to-severe psoriasis","volume":"235","author":"Gottlieb","year":"2019","journal-title":"Dermatology"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjd\/advance-article-pdf\/doi\/10.1093\/bjd\/ljad188\/51091873\/ljad188.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjd\/article-pdf\/189\/4\/437\/51605035\/ljad188.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjd\/article-pdf\/189\/4\/437\/51605035\/ljad188.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T17:14:15Z","timestamp":1694798055000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/189\/4\/437\/7195083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,13]]},"references-count":37,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,6,13]]},"published-print":{"date-parts":[[2023,9,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bjd\/ljad188","relation":{},"ISSN":["0007-0963","1365-2133"],"issn-type":[{"value":"0007-0963","type":"print"},{"value":"1365-2133","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,10]]},"published":{"date-parts":[[2023,6,13]]}}}