{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T17:43:41Z","timestamp":1785001421682,"version":"3.55.0"},"reference-count":46,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"German\u2013Israeli Foundation"},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["202208080206"],"award-info":[{"award-number":["202208080206"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Short anagen hair (SAH) is a rare paediatric hair disorder characterized by a short anagen phase, an inability to grow long scalp hair and a negative psychological impact. The genetic basis of SAH is currently unknown.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To perform molecular genetic investigations in 48 individuals with a clinical phenotype suggestive of SAH to identify, if any, the genetic basis of this condition.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Exome sequencing was performed in 27 patients diagnosed with SAH or with a complaint of short, nongrowing hair. The cohort was screened for variants with a minor allele frequency (MAF) &amp;lt; 5% in the general population and a Combined Annotation Dependent Depletion (CADD) score &amp;gt; 15, to identify genes whose variants were enriched in this cohort. Sanger sequencing was used for variant validation and screening of 21 additional individuals with the same clinical diagnosis and their relatives. Genetic association testing of SAH-related variants for male pattern hair loss (MPHL) was performed using UK Biobank data.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Analyses revealed that 20 individuals (42%) carried mono- or biallelic pathogenic variants in WNT10A. Rare WNT10A variants are associated with a phenotypic spectrum ranging from no clinical signs to severe ectodermal dysplasia. A significant association was found between WNT10A and SAH, and this was mostly observed in individuals with light-coloured hair and regression of the frontoparietal hairline. Notably, the most frequent variant in the cohort [c.682T&amp;gt;A;p.(Phe228Ile)] was in linkage disequilibrium with four common WNT10A variants, all of which have a known association with MPHL. Using UK Biobank data, our analyses showed that c.682T&amp;gt;A;p.(Phe228Ile) and one other variant identified in the SAH cohort are also associated with MPHL, and partially explain the known associations between WNT10A and MPHL.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our results suggest that WNT10A is associated with SAH and that SAH has a genetic overlap with the common phenotype MPHL. The presumed shared biologic effect of WNT10A variants in SAH and MPHL is a shortening of the anagen phase. Other factors, such as modifier genes and sex, may also play a role in the clinical manifestation of hair phenotypes associated with the WNT10A locus.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjd\/ljad314","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T10:11:09Z","timestamp":1693995069000},"page":"741-749","source":"Crossref","is-referenced-by-count":14,"title":["Short anagen hair syndrome: association with mono- and biallelic variants in <i>WNT10A<\/i> and a genetic overlap with male pattern hair loss"],"prefix":"10.1093","volume":"189","author":[{"given":"Nicole","family":"Cesarato","sequence":"first","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnes","family":"Schwieger-Briel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dermatology, University Children\u2019s Hospital Zurich , Zurich , Switzerland"},{"name":"Department of Dermatology, Medical Center \u2013 University of Freiburg , Freiburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmina","family":"Gossmann","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina K","family":"Henne","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Hillmann","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin , Berlin , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonie H","family":"Frommherz","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, Ludwig-Maximilian-University of Munich , Munich , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Wehner","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Xiong","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Thiele","sequence":"additional","affiliation":[{"name":"Cologne Center for Genomics, University of Cologne , Cologne , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinzenz","family":"Oji","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospital of Muenster , Muenster , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donatella","family":"Milani","sequence":"additional","affiliation":[{"name":"Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iliana","family":"Tantcheva-Poor","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine and University Hospital Cologne, University of Cologne , Cologne , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Giehl","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, Ludwig-Maximilian-University of Munich , Munich , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina","family":"F\u00f6lster-Holst","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, University Hospital Schleswig-Holstein , Kiel , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Teichler","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dermatology, Catholic Children's Hospital Wilhelmstift , Hamburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Braeckmans","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dermatology, Catholic Children's Hospital Wilhelmstift , Hamburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H","family":"Hoeger","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dermatology, Catholic Children's Hospital Wilhelmstift , Hamburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Jones","sequence":"additional","affiliation":[{"name":"Clinical Genetics Department, Nottingham University Hospitals NHS Trust , Nottingham , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Frank","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, University Medical Center G\u00f6ttingen , G\u00f6ttingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Weibel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dermatology, University Children\u2019s Hospital Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Blume-Peytavi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin , Berlin , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henning","family":"Hamm","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology, and Allergology, University Hospital W\u00fcrzburg , W\u00fcrzburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus M","family":"N\u00f6then","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Geyer","sequence":"additional","affiliation":[{"name":"Institute of Structural Biology, University of Bonn, Medical Faculty and University Hospital Bonn , Bonn , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Heilmann-Heimbach","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F Buket","family":"Basmanav","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5024-3623","authenticated-orcid":false,"given":"Regina C","family":"Betz","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,6]]},"reference":[{"key":"2023122117541236900_ljad314-B1","first-page":"30","article-title":"Short anagen syndrome","volume":"2","author":"Whitmore","year":"1999","journal-title":"J Clin Dermatol"},{"key":"2023122117541236900_ljad314-B2","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1365-2133.2000.03720.x","article-title":"Congenital hypotrichosis due to short anagen","volume":"143","author":"Barraud-Klenovsek","year":"2000","journal-title":"Br J Dermatol"},{"key":"2023122117541236900_ljad314-B3","doi-asserted-by":"crossref","first-page":"e349","DOI":"10.1111\/1346-8138.15494","article-title":"Short anagen syndrome: a unique short hair syndrome without any characteristic hair morphological abnormality","volume":"47","author":"Segawa","year":"2020","journal-title":"J Dermatol"},{"key":"2023122117541236900_ljad314-B4","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1111\/pde.14750","article-title":"Short anagen syndrome: a case series and algorithm for diagnosis","volume":"38","author":"Starace","year":"2021","journal-title":"Pediatr Dermatol"},{"key":"2023122117541236900_ljad314-B5","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/pde.13478","article-title":"Short anagen syndrome: case series and literature review","volume":"35","author":"Oberlin","year":"2018","journal-title":"Pediatr Dermatol"},{"key":"2023122117541236900_ljad314-B6","doi-asserted-by":"crossref","first-page":"e279","DOI":"10.1016\/j.jaad.2012.06.012","article-title":"Short anagen syndrome in a girl with curly dark hair and consanguineous parents","volume":"67","author":"Doche","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"2023122117541236900_ljad314-B7","doi-asserted-by":"crossref","first-page":"S130","DOI":"10.1016\/j.jaad.2004.12.029","article-title":"Short anagen syndrome","volume":"53","author":"Antaya","year":"2005","journal-title":"J Am Acad Dermatol"},{"key":"2023122117541236900_ljad314-B8","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/pde.15002","article-title":"The psychologic impact of loose anagen syndrome and short anagen syndrome","volume":"39","author":"Randolph","year":"2022","journal-title":"Pediatr Dermatol"},{"key":"2023122117541236900_ljad314-B9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0256846","article-title":"Evidence for a functional interaction of WNT10A and EBF1 in male-pattern baldness","volume":"16","author":"Hochfeld","year":"2021","journal-title":"PLOS ONE"},{"key":"2023122117541236900_ljad314-B10","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1038\/s41467-017-01490-8","article-title":"GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk","volume":"8","author":"Pirastu","year":"2017","journal-title":"Nat Commun"},{"key":"2023122117541236900_ljad314-B11","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1038\/jid.2013.43","article-title":"Androgenetic alopecia: identification of four genetic risk loci and evidence for the contribution of WNT signaling to its etiology","volume":"133","author":"Heilmann","year":"2013","journal-title":"J Invest Dermatol"},{"key":"2023122117541236900_ljad314-B12","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-018-07862-y","article-title":"Dissection of genetic variation and evidence for pleiotropy in male pattern baldness","volume":"9","author":"Yap","year":"2018","journal-title":"Nat Commun"},{"key":"2023122117541236900_ljad314-B13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1006594","article-title":"Genetic prediction of male pattern baldness","volume":"13","author":"Hagenaars","year":"2017","journal-title":"PLOS Genet"},{"key":"2023122117541236900_ljad314-B14","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.ajhg.2016.10.004","article-title":"Mutations in three genes encoding proteins involved in hair shaft formation cause\u00a0\u00aduncombable hair syndrome","volume":"99","author":"\u00dc Basmanav","year":"2016","journal-title":"Am J Hum Genet"},{"key":"2023122117541236900_ljad314-B15","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13073-021-00835-9","article-title":"CADD-splice-improving genome-wide variant effect prediction using deep learning-derived splice scores","volume":"13","author":"Rentzsch","year":"2021","journal-title":"Genome Med"},{"key":"2023122117541236900_ljad314-B16","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nmeth0410-248","article-title":"A method and server for predicting damaging missense mutations","volume":"7","author":"Adzhubei","year":"2010","journal-title":"Nat Methods"},{"key":"2023122117541236900_ljad314-B17","volume-title":"R: A Language and Environment for Statistical Computing","year":"2012"},{"key":"2023122117541236900_ljad314-B18","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/s41586-020-2308-7","article-title":"The mutational constraint spectrum quantified from variation in 141,456 humans","volume":"581","author":"Karczewski","year":"2020","journal-title":"Nature"},{"key":"2023122117541236900_ljad314-B19","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.1093\/bioinformatics\/btv402","article-title":"LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants","volume":"31","author":"Machiela","year":"2015","journal-title":"Bioinformatics"},{"key":"2023122117541236900_ljad314-B20","doi-asserted-by":"crossref","first-page":"W296","DOI":"10.1093\/nar\/gky427","article-title":"SWISS-MODEL: homology modelling of protein structures and complexes","volume":"46","author":"Waterhouse","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"2023122117541236900_ljad314-B21","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/s41594-019-0216-z","article-title":"Crystal structure of a mammalian Wnt-frizzled complex","volume":"26","author":"Hirai","year":"2019","journal-title":"Nat Struct Mol Biol"},{"key":"2023122117541236900_ljad314-B22","doi-asserted-by":"crossref","first-page":"4541","DOI":"10.1038\/s41467-021-24731-3","article-title":"Cryo-EM structure of human Wntless in complex with Wnt3a","volume":"12","author":"Zhong","year":"2021","journal-title":"Nat Commun"},{"key":"2023122117541236900_ljad314-B23","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","article-title":"Highly accurate protein structure prediction with AlphaFold","volume":"596","author":"Jumper","year":"2021","journal-title":"Nature"},{"key":"2023122117541236900_ljad314-B24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13742-015-0047-8","article-title":"Second-generation PLINK: rising to the challenge of larger and richer datasets","volume":"4","author":"Chang","year":"2015","journal-title":"Gigascience"},{"key":"2023122117541236900_ljad314-B25","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1038\/s41588-020-00735-5","article-title":"Functionally informed fine-mapping and polygenic localization of complex trait heritability","volume":"52","author":"Weissbrod","year":"2020","journal-title":"Nat Genet"},{"key":"2023122117541236900_ljad314-B26","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1111\/rssb.12388","article-title":"A simple new approach to variable selection in regression, with application to genetic fine mapping","volume":"82","author":"Wang","year":"2020","journal-title":"J R Stat Soc Ser B Stat Methodol"},{"key":"2023122117541236900_ljad314-B27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1010299","article-title":"Fine-mapping from summary data with the \u201cSum of Single Effects\u201d model","volume":"18","author":"Zou","year":"2022","journal-title":"PLOS Genet"},{"key":"2023122117541236900_ljad314-B28","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ajhg.2009.06.001","article-title":"WNT10A mutations are a frequent cause of a broad spectrum of ectodermal dysplasias with sex-biased manifestation pattern in heterozygotes","volume":"85","author":"Bohring","year":"2009","journal-title":"Am J Hum Genet"},{"key":"2023122117541236900_ljad314-B29","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1111\/bjd.20601","article-title":"WNT10A, dermatology and dentistry","volume":"185","author":"Doolan","year":"2021","journal-title":"Br J Dermatol"},{"key":"2023122117541236900_ljad314-B30","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2218238120","article-title":"Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination","volume":"120","author":"Tsutsumi","year":"2023","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2023122117541236900_ljad314-B31","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1002\/humu.21384","article-title":"Only four genes (EDA1, EDAR, EDARADD, and WNT10A) account for 90% of hypohidrotic\/anhidrotic ectodermal dysplasia cases","volume":"32","author":"Cluzeau","year":"2011","journal-title":"Hum Mutat"},{"key":"2023122117541236900_ljad314-B32","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1186\/s13023-019-1251-x","article-title":"EDA, EDAR, EDARADD and WNT10A allelic variants in patients with ectodermal derivative impairment in the Spanish population","volume":"14","author":"Martinez-Romero","year":"2019","journal-title":"Orphanet J Rare Dis"},{"key":"2023122117541236900_ljad314-B33","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00439-013-1360-x","article-title":"WNT10A variants are associated with non-syndromic tooth agenesis in the general population","volume":"133","author":"Song","year":"2014","journal-title":"Hum Genet"},{"key":"2023122117541236900_ljad314-B34","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1002\/ajmg.a.35747","article-title":"Mutations in WNT10A are frequently involved in oligodontia associated with minor signs of ectodermal dysplasia","volume":"161A","author":"Plaisancie","year":"2013","journal-title":"Am J Med Genet A"},{"key":"2023122117541236900_ljad314-B35","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1002\/ajmg.a.36388","article-title":"Tricho-odonto-onycho-dermal dysplasia and WNT10A mutations","volume":"164A","author":"Kantaputra","year":"2014","journal-title":"Am J Med Genet A"},{"key":"2023122117541236900_ljad314-B36","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/mgg3.111","article-title":"Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds","volume":"3","author":"Yang","year":"2015","journal-title":"Mol Genet Genom Med"},{"key":"2023122117541236900_ljad314-B37","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/exd.12965","article-title":"Hunting the genes in male-pattern alopecia: how important are they, how close are we and what will they tell us?","volume":"25","author":"Heilmann-Heimbach","year":"2016","journal-title":"Exp Dermatol"},{"key":"2023122117541236900_ljad314-B38","doi-asserted-by":"crossref","first-page":"15397","DOI":"10.1038\/ncomms15397","article-title":"WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation","volume":"8","author":"Xu","year":"2017","journal-title":"Nat Commun"},{"key":"2023122117541236900_ljad314-B39","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0925-4773(01)00452-X","article-title":"Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis","volume":"107","author":"Reddy","year":"2001","journal-title":"Mech Dev"},{"key":"2023122117541236900_ljad314-B40","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/nature05659","article-title":"Scratching the surface of skin development","volume":"445","author":"Fuchs","year":"2007","journal-title":"Nature"},{"key":"2023122117541236900_ljad314-B41","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1111\/bjd.18356","article-title":"Deciphering the molecular morphology of the human hair cycle: Wnt signalling during the telogen-anagen transformation","volume":"182","author":"Hawkshaw","year":"2020","journal-title":"Br J Dermatol"},{"key":"2023122117541236900_ljad314-B42","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1111\/j.1365-2133.2010.09703.x","article-title":"Phenotypic variability associated with WNT10A nonsense mutations","volume":"162","author":"Van Geel","year":"2010","journal-title":"Br J Dermatol"},{"key":"2023122117541236900_ljad314-B43","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1177\/0022034520962728","article-title":"Functional effects of WNT10A rare variants associated with tooth agenesis","volume":"100","author":"Zeng","year":"2021","journal-title":"J Dent Res"},{"key":"2023122117541236900_ljad314-B44","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1111\/ijd.12150","article-title":"Minoxidil improved hair density in an Asian girl with short anagen syndrome: a case report and review of literature","volume":"55","author":"Cheng","year":"2016","journal-title":"Int J Dermatol"},{"key":"2023122117541236900_ljad314-B45","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jdermsci.2011.01.013","article-title":"Minoxidil activates \u03b2-catenin pathway in human dermal papilla cells: a possible explanation for its anagen prolongation effect","volume":"62","author":"Kwack","year":"2011","journal-title":"J Dermatol Sci"},{"key":"2023122117541236900_ljad314-B46","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1067\/mjd.2002.124088","article-title":"A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men","volume":"47","author":"Olsen","year":"2002","journal-title":"J Am Acad Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjd\/advance-article-pdf\/doi\/10.1093\/bjd\/ljad314\/51840344\/ljad314.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjd\/article-pdf\/189\/6\/741\/54729145\/ljad314.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjd\/article-pdf\/189\/6\/741\/54729145\/ljad314.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T19:24:58Z","timestamp":1703186698000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/189\/6\/741\/7261337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,6]]},"references-count":46,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,9,6]]},"published-print":{"date-parts":[[2023,11,16]]}},"URL":"https:\/\/doi.org\/10.1093\/bjd\/ljad314","relation":{},"ISSN":["0007-0963","1365-2133"],"issn-type":[{"value":"0007-0963","type":"print"},{"value":"1365-2133","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,12]]},"published":{"date-parts":[[2023,9,6]]}}}