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This study analysed the microbiome of lesional, perilesional and healthy skin samples, and found significant differences, including increased Mycoplasma and Bacillus in lesional skin. The reduction of Cutibacterium variants D1 and H1 in HS-affected skin highlights their potential as therapeutic targets, suggesting a strategy of topical replacement therapy.<\/jats:p>","DOI":"10.1093\/bjd\/ljae371","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T18:20:33Z","timestamp":1727806833000},"page":"359-361","source":"Crossref","is-referenced-by-count":3,"title":["Microbiome characterization of skin biopsies in Spanish patients with hidradenitis suppurativa shows a decrease in D1 and H1 lineages of <i>Cutibacterium acnes<\/i>"],"prefix":"10.1093","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6134-5155","authenticated-orcid":false,"given":"Jorge","family":"Roman\u00ed","sequence":"first","affiliation":[{"name":"Department of Dermatology, Hospital General de Granollers , Barcelona 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