{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:43:39Z","timestamp":1790747019472,"version":"4.1.0"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council of Australia","doi-asserted-by":"publisher","award":["1185416"],"award-info":[{"award-number":["1185416"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council of Australia","doi-asserted-by":"publisher","award":["1155413"],"award-info":[{"award-number":["1155413"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council of Australia","doi-asserted-by":"publisher","award":["2026567"],"award-info":[{"award-number":["2026567"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Increased levels of skin detection activities are suspected of driving recent rapid increases in melanoma incidence. While ecological studies report rising rates of skin biopsies in many industrialized populations, few studies have accessed individual-level clinical data to test the hypothesis that people exposed to skin screening and surveillance go on to experience higher levels of biopsies and excisions, and a higher incidence of melanoma.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To measure the incidence rates of detection events and melanoma diagnoses in a national cohort during follow-up, stratified according to screening or surveillance activities in the index year.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a prospective cohort study of 10 674 200 adults using linked data from Australia\u2019s universal health insurance scheme (2011\u20132016). Participants who underwent biopsies or who were diagnosed with skin cancer in 2011\u201312 were excluded. We then defined participants as surveilled, screened or unscreened for skin cancer based on medical claims occurring in 2013. We compared rates of biopsies, excisions for suspected melanoma and excisions for histologically confirmed melanoma during follow-up (2014\u20132016).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>After adjusting for sociodemographic factors, screened people were significantly more likely than unscreened people to undergo skin biopsies [rate ratio (RR) 2.59, 95% confidence interval (CI) 2.56\u20132.63], excisions for suspected melanoma (RR 2.57, 95% CI 2.53\u20132.60) and excisions for confirmed melanoma (hazard ratio 3.32, 95% CI 3.24\u20133.40) during follow-up. Similarly elevated rates of subsequent diagnostic events were observed for the surveilled group. Importantly, rates of detection and rates of melanoma remained elevated in each of the subsequent years of follow-up among those who were screened or surveilled in the index year.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>People undergoing skin screening or surveillance subsequently experience higher rates of diagnostic scrutiny and higher rates of melanoma.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjd\/ljae372","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T18:21:24Z","timestamp":1727806884000},"page":"238-246","source":"Crossref","is-referenced-by-count":6,"title":["Melanoma as a detection-dependent cancer: proxy measures of screening and surveillance associated with 3-year incidence of detection procedures for skin cancer in\u00a0a national prospective study"],"prefix":"10.1093","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1462-4968","authenticated-orcid":false,"given":"Nirmala","family":"Pandeya","sequence":"first","affiliation":[{"name":"Department of Population Health, QIMR Berghofer Medical Research Institute , Herston, QLD ,","place":["Australia"]},{"name":"Faculty of Medicine, University of Queensland , Brisbane, QLD ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4483-1888","authenticated-orcid":false,"given":"Catherine M","family":"Olsen","sequence":"additional","affiliation":[{"name":"Department of Population Health, QIMR Berghofer Medical Research Institute , Herston, QLD ,","place":["Australia"]},{"name":"Faculty of Medicine, University of Queensland , Brisbane, QLD ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel E","family":"Neale","sequence":"additional","affiliation":[{"name":"Department of Population Health, QIMR Berghofer Medical Research Institute , Herston, QLD ,","place":["Australia"]},{"name":"Faculty of Medicine, University of Queensland , Brisbane, QLD ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2563-9559","authenticated-orcid":false,"given":"David C","family":"Whiteman","sequence":"additional","affiliation":[{"name":"Department of Population Health, QIMR Berghofer Medical Research Institute , Herston, QLD ,","place":["Australia"]},{"name":"Faculty of Medicine, University of Queensland , Brisbane, QLD ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,10,1]]},"reference":[{"key":"2025012411194516100_ljae372-B1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/(SICI)1096-9098(199802)67:2<73::AID-JSO1>3.0.CO;2-I","article-title":"Non-metastasizing melanoma?","volume":"67","author":"Burton","year":"1998","journal-title":"J Surg Oncol"},{"key":"2025012411194516100_ljae372-B2","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/00008390-199404000-00005","article-title":"Recent incidence trends imply a nonmetastasizing form of invasive melanoma","volume":"4","author":"Burton","year":"1994","journal-title":"Melanoma Res"},{"key":"2025012411194516100_ljae372-B3","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1002\/ijc.2910550512","article-title":"An analysis of a melanoma epidemic","volume":"55","author":"Burton","year":"1993","journal-title":"Int J 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