{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T22:41:19Z","timestamp":1791844879683,"version":"4.3.4"},"reference-count":82,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Mycosis fungoides (MF) is considered rare in children and adolescents. Accumulating experience indicates that compared with adult patients, almost all paediatric patients with MF are diagnosed at an early stage of disease, exhibit higher rates of atypical presentations and follow a notably indolent course. Despite the need for special staging\/investigations specific for children and adolescents, the staging of paediatric MF is currently based primarily on standard practice in adults. The aim of this work was to develop staging recommendations specifically designed for MF in children and adolescents, on behalf of the three largest societies for cutaneous lymphomas, the International Society for Cutaneous Lymphomas, the European Organisation for Research and Treatment of Cancer \u2013 Cutaneous Lymphoma Tumor Group, and the United States Cutaneous Lymphoma Consortium. We developed this guideline through an international expert consensus process and in accordance with the EQUATOR Network\u2019s recommendations for guideline development. A modified Delphi process was conducted, using questionnaires covering topics including the definition, characteristics and staging of paediatric MF. Two rounds of expert feedback were conducted, with an additional hybrid consensus meeting. We reached a consensus that the term \u2018paediatric MF\u2019 should be reserved for MF diagnosed at \u2264 18\u2005years of age. Panellists specified the unique clinical characteristics of paediatric MF, including a high prevalence of hypopigmented and folliculotropic variants, and reached a consensus on the indolent nature of the disease during childhood and adolescence with rare progression to advanced stage. The consensus reached recommends that while the staging approach is largely similar to that in adults, imaging for early-stage paediatric MF should rely on ultrasound of the lymph nodes if indicated, rather than computed tomography with contrast or integrated with positron emission tomography. Along with this, clinicians should be aware that in children, palpable lymph nodes are common owing to the increased incidence of infectious diseases. In summary, this guideline addresses the major clinical characteristics of paediatric MF, which differ from those in adults, and provides practical staging recommendations considering the safety implications specific for this age group.<\/jats:p>","DOI":"10.1093\/bjd\/ljaf199","type":"journal-article","created":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T07:18:04Z","timestamp":1748071084000},"page":"405-414","source":"Crossref","is-referenced-by-count":13,"title":["ISCL\/EORTC-CLTG\/USCLC recommendations for the diagnosis, staging and treatment of early-stage paediatric mycosis fungoides: a modified Delphi consensus. Part one: diagnosis and staging"],"prefix":"10.1093","volume":"193","author":[{"given":"Emmilia","family":"Hodak","sequence":"first","affiliation":[{"name":"Division of Oncology, Davidoff Medical Center, Rabin Medical Center, Beilinson Hospital, Faculty of Medical and Health Sciences, Tel Aviv University , Tel Aviv ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris","family":"Amitay-Laish","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Rabin Medical Center, Beilinson Hospital, Faculty of Medical and Health Sciences, Tel Aviv University , Tel Aviv ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Bagot","sequence":"additional","affiliation":[{"name":"Dermatology Department, Saint-Louis Hospital, AP-HP, Universit\u00e9 Paris Cit\u00e9 , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7053-7431","authenticated-orcid":false,"given":"Maxime","family":"Battistella","sequence":"additional","affiliation":[{"name":"Pathology Department, Saint-Louis Hospital , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Ben Amitai","sequence":"additional","affiliation":[{"name":"Pediatric Dermatology Unit, Schneider Children\u2019s Medical Center of Israel , Petach Tikva ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Cozzio","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Canton Hospital St Gallen ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeleine","family":"Duvic","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University of Texas, MD Anderson Cancer Center , Houston, TX ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Ferenczi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University of Connecticut School of Medicine , Farmington, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine","family":"Foss","sequence":"additional","affiliation":[{"name":"Yale Cancer Center, Yale School of Medicine , New Haven, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larisa","family":"Geskin","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Columbia University Irving Medical Center , New York, NY ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5478-8735","authenticated-orcid":false,"given":"Emmanuella","family":"Guenova","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; and University Institute and Clinic for Immunodermatology, Medical Faculty, Johannes Kepler University , Linz ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youn H","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Oncology, Department of Medicine, Stanford University , Stanford, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark Jean-Aan","family":"Koh","sequence":"additional","affiliation":[{"name":"Department of Dermatology, KK Women\u2019s and Children\u2019s Hospital ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Molg\u00f3","sequence":"additional","affiliation":[{"name":"Departamento de Dermatolog\u00eda, Facultad de Medicina, Pontificia Universidad Cat\u00f3lica de Chile , Santiago 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,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amra","family":"Osmancevic","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg ,","place":["Sweden"]},{"name":"Region V\u00e4stra G\u00f6taland, Sahlgrenska University Hospital, Department of Dermatology and Venereology , Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelia","family":"Papadavid","sequence":"additional","affiliation":[{"name":"Attikon General University Hospital, National and Kapodistrian University of Athens , Athens ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Bin","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Kosin University College of Medicine , Busan ,","place":["South 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