{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T15:13:28Z","timestamp":1779203608526,"version":"3.51.4"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,19]]},"abstract":"<jats:title>Lay Summary<\/jats:title>\n                  <jats:p>Nodular prurigo (NP) is a chronic skin condition. Lesions can be either single or widespread on the body. Thus, it can have a negative impact on a person\u2019s quality of life. The exact cause of NP is unknown, as several mechanisms play a role. These mechanisms sometimes overlap between physical and brain\u2013behavioural elements. Dermatologists diagnose NP based on a history of long-lasting itching and scratching.<\/jats:p>\n                  <jats:p>A Guideline Development Group met to produce a new guideline for treating people with NP. The group included consultant dermatologists, a psychotherapist, dermatology trainees, a general practitioner and people with lived experience of NP. The group identified and reviewed the current literature on treating NP. They discussed the findings at length before producing a set of recommendations. The guideline will provide up-to-date management guidance for healthcare practitioners.<\/jats:p>\n                  <jats:p>Initial steps included taking a full history and examination of patients. This included causes of itch, patient education and reversing the itch\u2013scratch habit. The first treatment option is usually topical therapy (applied to the skin). If this fails, other options include phototherapy and oral medications. Further treatments include nonsedating antihistamines and low-dose antidepressants. Steroid injections or cryotherapy (freezing with liquid nitrogen) are options for single lesions.<\/jats:p>\n                  <jats:p>The guideline provides recommendations for treating people with NP. It also includes recommendations for future research and audit points for hospitals. A patient information leaflet is available on the British Association of Dermatologists\u2019 website (https:\/\/www.skinhealthinfo.org.uk\/condition\/nodular-prurigo).<\/jats:p>","DOI":"10.1093\/bjd\/ljag070","type":"journal-article","created":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T12:48:51Z","timestamp":1772628531000},"page":"1035-1045","source":"Crossref","is-referenced-by-count":0,"title":["British Association of Dermatologists living guideline for\u00a0managing people with nodular prurigo (prurigo nodularis) 2025"],"prefix":"10.1093","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4235-2085","authenticated-orcid":false,"given":"George W M","family":"Millington","sequence":"first","affiliation":[{"name":"Norfolk and Norwich University Hospitals NHS Foundation Trust , Norwich ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5293-0953","authenticated-orcid":false,"given":"Priya 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,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0135-6458","authenticated-orcid":false,"given":"Jane C","family":"Sterling","sequence":"additional","affiliation":[{"name":"Addenbrooke\u2019s Hospital, Cambridge University Hospitals NHS Foundation Trust , Cambridge ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenny\u00a0R","family":"Hughes","sequence":"additional","affiliation":[{"name":"Princess of Wales Hospital, Cwm Taf Morgannwg University Health Board , Bridgend ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0812-7044","authenticated-orcid":false,"given":"Marieta","family":"Papanikolaou","sequence":"additional","affiliation":[{"name":"Norfolk and Norwich University Hospitals NHS Foundation Trust , Norwich ,","place":["UK"]},{"name":"Dr Philip Frost Department of Dermatology and Cutaneous Surgery, Miami Itch Centre, 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