{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T07:45:48Z","timestamp":1791791148586,"version":"4.3.4"},"reference-count":6,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23AR077073"],"award-info":[{"award-number":["K23AR077073"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001582","name":"Dermatology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001582","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Prurigo nodularis (PN) is a chronic inflammatory skin disease with a poorly understood pathogenesis. We performed single-cell RNA sequencing on skin samples from patients with PN to characterize tissue-resident memory T-cell (TRM) subsets. Our findings reveal heterogeneous populations of PN CD4 TRMs in relation to the transcriptomes of atopic dermatitis and psoriasis, with immunological heterogeneity correlating with treatment response.<\/jats:p>","DOI":"10.1093\/bjd\/ljag324","type":"journal-article","created":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T11:52:06Z","timestamp":1786189926000},"source":"Crossref","is-referenced-by-count":0,"title":["Single-cell RNA sequencing reveals a distinct resident memory T-cell phenotype in prurigo nodularis"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4737-8740","authenticated-orcid":false,"given":"Jay R","family":"Patel","sequence":"first","affiliation":[{"name":"Department of Dermatology, University of Maryland School of Medicine , Baltimore, MD ,","place":["USA"]},{"name":"Maryland Itch Center, University of Maryland School of Medicine , Baltimore, MD 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