{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:59:29Z","timestamp":1791827969232,"version":"4.3.4"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1167","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Health Commission Foundation of Heilongjiang Province, China","award":["20230909020381"],"award-info":[{"award-number":["20230909020381"]}]},{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province, China","doi-asserted-by":"crossref","award":["LH2022H033"],"award-info":[{"award-number":["LH2022H033"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>This study aimed to assess the diagnostic efficacy of the ovarian adnexal reporting and data system (O-RADS) and ultrasound (US) and its sub-classification system for distinguishing ovarian masses.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>O-RADS US was used for the retrospective analysis of 606 ovarian masses of Chinese from 2 medical centres by 2 gynaecologic sonographers with varying experience. The O-RADS 4 categories masses were further sub-classified into O-RADS 4a and O-RADS 4b through 3 different approaches (O-RADS A1\/A2\/A3).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The AUC of O-RADS US for differentiating benign from malignant ovarian masses was 0.927 (95% CI, 0.903-0.946, P\u2009&amp;lt;\u2009.001). The optimal cut-off value for predicting malignancy was &amp;gt;O-RADS 3, with sensitivity and specificity of 98.60% and 68.90%, respectively. The diagnostic efficacy of the 3 sub-classification systems surpassed that of O-RADS US (P\u2009&amp;lt;\u2009.05). Specifically, A2 approach (within O-RADS 4 lesions, unilocular and multilocular cysts with solid components were sub-classified as O-RADS 4b, whereas the remaining O-RADS 4 lesions were sub-classified as O-RADS 4a) resulted in an AUC of 0.942 (95% CI, 0.921-0.960, P\u2009&amp;lt;\u2009.001). The best cut-off value predicting malignancy was &amp;gt;O-RADS 4a, exhibiting relatively high specificity (82.51%) and maintaining a high sensitivity (93.01%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The diagnostic efficacy of O-RADS US for identifying ovarian tumours is good, but specificity is slightly lower. This study enhanced diagnostic specificity after subclassifying O-RADS 4 lesions, especially A2 approach. It holds significant clinical value for Chinese women and merits further clinical promotion and application.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge<\/jats:title>\n                  <jats:p>The sub-classification of O-RADS US allows better identifying ovarian tumours, facilitating informed preoperative clinical management and diagnosis.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjr\/tqae247","type":"journal-article","created":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T05:28:42Z","timestamp":1735536522000},"page":"448-457","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic value of the ovarian adnexal reporting and data system ultrasound in ovarian masses: a 2-center study"],"prefix":"10.1093","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-4602-3459","authenticated-orcid":false,"given":"Fei","family":"Teng","sequence":"first","affiliation":[{"name":"In-Patient Ultrasound Department, Second Affiliated Hospital of Harbin Medical University , Harbin, 150081,","place":["China"]},{"name":"Ultrasound Department, Fourth Affiliated Hospital of Harbin Medical University , Harbin, 150001,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honglei","family":"Xie","sequence":"additional","affiliation":[{"name":"Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University , Harbin, 150081,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wei","sequence":"additional","affiliation":[{"name":"In-Patient Ultrasound Department, Second Affiliated Hospital of Harbin Medical University , Harbin, 150081,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dehong","family":"Che","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Second Affiliated Hospital of Harbin Medical University , Harbin, 150081,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Wang","sequence":"additional","affiliation":[{"name":"In-Patient Ultrasound Department, Second Affiliated Hospital of Harbin Medical University , Harbin, 150081,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengwei","family":"Wu","sequence":"additional","affiliation":[{"name":"In-Patient Ultrasound Department, Second Affiliated Hospital of Harbin Medical University , Harbin, 150081,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"He","sequence":"additional","affiliation":[{"name":"Ultrasound Department, Fourth Affiliated 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