{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T17:39:15Z","timestamp":1788025155001,"version":"build-2784847793"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"1167","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Abdominal wall endometriosis (AWE) consists of endometrial tissue between the peritoneum and the abdominal wall. The established treatment involves amenorrheic drugs\u2014not always successful and tolerated\u2014or invasive surgery. In this scenario, minimally invasive techniques such as cryoablation are a potential option. In this study, we primarily aimed to evaluate the efficacy of percutaneous cryoablation in reducing pain scores of AWE patients and analyze their satisfaction with the procedure and its related adverse events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>MEDLINE, EMBASE, and Cochrane\u2019s databases were systematically searched for studies that employed percutaneous cryoablation therapy for AWE and reported any of the outcomes of interest. The primary outcome was the reduction in the visual analog scale (VAS) score after treatment. R Software was used for the statistical analysis. Heterogeneity was assessed using I2 statistics. The Risk Of Bias In Non-Randomized Studies\u2014of Interventions framework assessed potential bias in each selected study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We included 4 studies, containing 126 patients. All articles were retrospective studies. The difference between the VAS scores before and after treatment was on average 5.97 points (95% CI 5.42-6.52; P\u2009&amp;lt;.01; I2\u2009=\u20090%). The pooled satisfaction rate among patients in the selected studies was 93.1% (95% CI 88.66-97.34; P\u2009=\u2009.51; I2\u2009=\u20090%). The pooled prevalence of adverse events was only 5.48% (95% CI 1.71-11.20; P\u2009=\u2009.58; I2\u2009=\u20090%). Bias analysis showed an overall moderate risk in all included articles.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our study demonstrated that cryoablation could reduce pain complaints in patients, while presenting a low incidence rate of adverse effects. Randomized clinical trials with a larger number of patients are necessary for greater conclusions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge<\/jats:title>\n                  <jats:p>(1) AWE affects about 3.5% of women. The standard treatment is invasive surgery. (2) This meta-analysis demonstrated that cryoablation can effectively reduce pain scores while presenting a low rate of adverse effects. (3) Cryoablation is a feasible treatment for AWE, furthermore allowing shorter hospital stays and few complications for the patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjr\/tqaf009","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T16:08:36Z","timestamp":1737043716000},"page":"345-353","source":"Crossref","is-referenced-by-count":6,"title":["Percutaneous cryoablation therapy for abdominal wall endometriosis: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5101-8356","authenticated-orcid":false,"given":"Let\u00edcia Helena","family":"Ka\u00e7a do Carmo","sequence":"first","affiliation":[{"name":"Department of Medical Imaging, Hematology and Clinical Oncology, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo , Ribeir\u00e3o Preto, S\u00e3o Paulo, 14049-900,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Brito Ceolin de Faria","sequence":"additional","affiliation":[{"name":"Vila Velha University , Vila Velha, Espirito Santo, 29102-920,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00edlia","family":"da Cruz Fagundes","sequence":"additional","affiliation":[{"name":"Imaging Diagnostic Center, Oswaldo Cruz German Hospital , S\u00e3o Paulo, S\u00e3o Paulo, 01323-020,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Costa de Oliveira Lima","sequence":"additional","affiliation":[{"name":"Pontifical Catholic University of Campinas Medical School , Campinas, S\u00e3o Paulo, 13034-685,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Verdan Moreira","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital of the Federal University of Juiz de Fora , Juiz de Fora, Minas Gerais, 36036-900,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8702-5541","authenticated-orcid":false,"given":"Guilherme","family":"Strieder de Oliveira","sequence":"additional","affiliation":[{"name":"Diagnostic Radiology Department, Rio Grande do Sul Federal University , Porto Alegre, Rio Grande do Sul, 90010-150,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Vidal Le\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Musculoskeletal Radiology, University of Iowa , Iowa City, Iowa, 52242,","place":["United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuela","family":"Mendes Junqueira de Barros","sequence":"additional","affiliation":[{"name":"Jos\u00e9 do Ros\u00e1rio Velano University , Alfenas, Minas Gerais, 37132-440,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriana","family":"Mariussi","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Albert Einstein Hospital , S\u00e3o Paulo, S\u00e3o Paulo, 05652-900,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Moretti Monsignore","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, Hematology and Clinical Oncology, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo , Ribeir\u00e3o Preto, S\u00e3o Paulo, 14049-900,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Giansante Abud","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, Hematology and Clinical Oncology, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo , Ribeir\u00e3o Preto, S\u00e3o Paulo, 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