{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T04:16:40Z","timestamp":1750997800566,"version":"3.41.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"1171","license":[{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Joint Research Development"},{"name":"Shenkang and United Imaging on Clinical Research and Translation","award":["SKLY2022CRT201"],"award-info":[{"award-number":["SKLY2022CRT201"]}]},{"name":"Shanghai Municipal Key Clinical Specialty","award":["shslczdzk03202"],"award-info":[{"award-number":["shslczdzk03202"]}]},{"name":"Shanghai Municipal \u201cExplorer Plan\u201d","award":["24TS1411000"],"award-info":[{"award-number":["24TS1411000"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To evaluate the image quality of the free-breathing, non-ECG-multitasking T1 mapping and to compare T1 values, lesion area, and ROC curve with those derived from the traditional MOLLI sequence in ischaemic and non-ischaemic cardiomyopathy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In vitro, T1 values from CMR multitasking and MOLLI images were compared in 4 phantoms. In vivo studies included 108 patients (38 ischaemic cardiomyopathy, 70 non-ischaemic cardiomyopathy) and 31 healthy volunteers. All underwent mid-ventricular short-axis CMR Multitasking (free-breathing) and MOLLI (breath-held). Image quality was scored (4-point scale). T1 values and lesion areas were compared via linear regression, Bland-Altman analysis, and ROC curves (LGE as reference).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Phantom T1 values showed excellent agreement (Multitasking versus reference: R2\u2009=\u20090.99, P\u2009&amp;lt;\u2009.001). In vivo, multitasking strongly correlated with MOLLI for native T1 in healthy subjects (R2\u2009=\u20090.69), ischaemic (R2\u2009=\u20090.71), and non-ischaemic groups (R2\u2009=\u20090.81, all P\u2009&amp;lt;\u2009.001). Multitasking demonstrated superior image quality in patients with breath-holding difficulties and adverse heart rates (P\u2009&amp;lt;\u2009.001). MOLLI image quality declined with breath-holding difficulties, arrhythmia, and high BMI (P\u2009&amp;lt;\u2009.05); multitasking was less affected but still impacted by BMI (P\u2009&amp;lt;\u2009.05). Lesion areas showed no inter-sequence differences (P\u2009&amp;gt;\u2009.05). ROC analysis revealed comparable diagnostic accuracy between sequences in stable patients (P\u2009&amp;gt;\u2009.05), but superior multitasking performance in breath-holding difficulties and arrhythmia subgroups (P\u2009&amp;lt;\u2009.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Multitasking provides accurate T1 quantification and lesion delineation in cardiomyopathy, with enhanced robustness for patients with poor breath-holding or arrhythmia. BMI-related limitations warrant technical refinement.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge<\/jats:title>\n                  <jats:p>Free-breathing, non-ECG CMR multitasking achieves accurate T1 mapping in ischaemic\/non-ischaemic cardiomyopathy, overcoming ECG\/respiratory limitation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjr\/tqaf104","type":"journal-article","created":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T20:34:16Z","timestamp":1747082056000},"page":"1112-1123","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of free-breathing, non-ECG-triggered magnetic resonance T1 mapping derived from multitasking imaging at 3.0\u2009T in patients with ischaemic and non-ischaemic cardiomyopathy"],"prefix":"10.1093","volume":"98","author":[{"given":"Shiya","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiying","family":"Hua","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaqiong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongfei","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajun","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqi","family":"She","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Radiology, Zhongshan Hospital (Minhang Branch), Fudan University and Shanghai Geriatric Medical Center , Shanghai 200237,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiying","family":"Ge","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Radiology, Zhongshan Hospital (Minhang Branch), Fudan University and Shanghai Geriatric Medical Center , Shanghai 200237,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengsu","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinyin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 200032,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6810-2527","authenticated-orcid":false,"given":"Hang","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging , Shanghai 200032,","place":["China"]},{"name":"Department of Medical Imaging, Shanghai Medical School, Fudan University , Shanghai 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