{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T08:24:56Z","timestamp":1791447896445,"version":"4.3.3"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"1173","license":[{"start":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T00:00:00Z","timestamp":1751068800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014461","name":"Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014461","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012139","name":"The Royal Marsden NHS Foundation Trust","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012139","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000650","name":"The Institute of Cancer Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000650","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Royal Marsden Cancer Charity, and Cancer Research"},{"name":"Royal of College of Radiologists"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Transcatheter CT hepatic angiography (CTHA) enhances liver tumour ablation by enabling multiple direct intra-arterial contrast injections during a single procedure. We report the implementation of a single-room CTHA workflow using a mobile fluoroscopic C-arm, focusing on feasibility and safety.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A prospective service evaluation was conducted following a radiation risk assessment and training at an expert centre. Feasibility\u2014defined as the ability to integrate CTHA into a four-hour ablation session\u2014was assessed alongside technical success, which was defined as acquisition of CTHA images. All CTHA-related adverse events were recorded and graded using the Common Terminology Criteria for Adverse Events (CTCAE). Radiation dose, contrast volume, and tumour visualization were also documented.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Twenty patients (14 men, median age 66\u2009years) underwent 21 CTHA procedures (April\u2013September 2024). Feasibility and technical success were 100%, without any instance of CTHA-related complications. Median catheterization time was 10\u2009min16\u2009s, contrast dose was 174\u2009mL (7 acquisitions), and radiation dose-area product was 18.86\u2009Gy\u00b7cm2. Ninety-seven percent of tumours (32\/33) were visible. All these tumours were completely covered by an ablation zone using image fusion software.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Single-room CTHA using a mobile C-arm is feasible and safe for liver tumour ablation. This technique enhances tumour and ablation zone visibility whilst requiring low contrast volumes, enabling multiple acquisitions and real-time margin assessment. Our technique can be readily implemented without expensive infrastructure, holding significant promise in improving liver ablation outcomes and broadening access to advanced interventional oncology techniques.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge<\/jats:title>\n                  <jats:p>Single-room CTHA can be readily implemented in centres with catheterization experience, without expensive infrastructure. The method holds significant promise in improving liver ablation outcomes and broadening access to state-of-the-art interventional oncology techniques globally.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjr\/tqaf117","type":"journal-article","created":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T12:20:51Z","timestamp":1751113251000},"page":"1394-1402","source":"Crossref","is-referenced-by-count":2,"title":["Single-room transcatheter CT hepatic angiography for microwave liver ablation: a feasibility and safety study"],"prefix":"10.1093","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8504-2968","authenticated-orcid":false,"given":"Edward W","family":"Johnston","sequence":"first","affiliation":[{"name":"Interventional Radiology, The Royal Marsden Hospital , London SW36JJ,","place":["United Kingdom"]},{"name":"Radiotherapy and Imaging, Institute of Cancer Research , Sutton SM2 5NG,","place":["United 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