{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:09:41Z","timestamp":1760242181449,"version":"build-2065373602"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"1174","license":[{"start":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T00:00:00Z","timestamp":1750636800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC1004104"],"award-info":[{"award-number":["2018YFC1004104"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>We compared the predictive performance of apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM) parameters in assessing small for gestational age (SGA) pregnancies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Perspective study. Twenty-eight normal controls and 30 SGA pregnancies underwent IVIM scans on a 3.0\u2009T MRI scanner. The diffusion coefficient (D), pseudodiffusion coefficient (D*), and perfusion fraction (f) were calculated from the IVIM, and the ADC was derived from the IVIM sequence with monoexponential fitting of the IVIM data at b-values of 0 and 800\u2009s\/mm. All 4 parameters and AUC within the placenta were compared between normal and SGA pregnancies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>All of mean ADC ([1.69\u2009\u00b1\u20090.19]\u2009\u00d7\u200910\u22123\u2009mm2\/s vs [1.42\u2009\u00b1\u20090.28]\u2009\u00d7\u200910\u22123\u2009mm2\/s), D (1901.08\u2009\u00b1\u2009199.77\u2009\u00b5m2\/s vs 1635.17\u2009\u00b1\u2009244.18\u2009\u00b5m2\/s), D* (56\u2009445.78\u2009\u00b1\u20098125.91\u2009\u00b5m2\/s vs 47\u2009600.62\u2009\u00b1\u20097642.15\u2009\u00b5m2\/s), and f (33.35%\u2009\u00b1\u20093.36% vs 27.30\u2009\u00b1\u20093.48%) were significantly decreased in SGA pregnancies (P\u2009&amp;lt;\u2009.001 for all). The diagnostic performance of f (AUC\u2009=\u20090.896; sensitivity, 80.00%; specificity, 92.86%; cut-off value, 29.28%) was significantly better than ADC (AUC\u2009=\u20090.788; sensitivity, 86.67%; specificity, 70.83%; cut-off value, 1.63\u2009\u00d7\u200910\u22123\u2009mm2\/s; P\u2009=\u2009.035), D (AUC\u2009=\u20090.798; sensitivity, 70.00%; specificity, 82.14%; cut-off value, 1708.17\u2009\u00b5m2\/s; P\u2009=\u2009.041), and D* (AUC\u2009=\u20090.800; sensitivity, 63.33%; specificity, 89.29%; cut-off value, 48181.97\u2009\u00b5m2\/s; P\u2009=\u2009.044).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our study suggested that f, a perfusion parameter derived from IVIM, was a more powerful independent predictor than ADC and other IVIM parameters of SGA pregnancies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge<\/jats:title>\n                  <jats:p>This study compared the ADC and IVIM in diagnosing SGA.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjr\/tqaf136","type":"journal-article","created":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T22:18:47Z","timestamp":1751149127000},"page":"1615-1622","source":"Crossref","is-referenced-by-count":0,"title":["Use of diffusion-weighted magnetic resonance imaging to distinguish between normal and small for gestational age pregnancies: comparison of intravoxel incoherent motion derived parameters and apparent diffusion coefficient"],"prefix":"10.1093","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8353-0522","authenticated-orcid":false,"given":"Junshen","family":"He","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University , Guangzhou, 510515,","place":["China"]},{"name":"Department of Obstetrics and Gynecology, Faculty of Medical and Health Sciences, University of Auckland , Auckland, 1142,","place":["New Zealand"]},{"name":"Auckland Bioengineering Institute, University of Auckland , Auckland, 1010,","place":["New Zealand"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liqun","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University , Guangzhou, 510515,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nanfang Hospital, Southern Medical University , Guangzhou, 510515,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunlin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University , Guangzhou, 510515,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8196-4340","authenticated-orcid":false,"given":"Ping","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University , Guangzhou, 510515,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,6,23]]},"reference":[{"key":"2025101113172388500_tqaf136-B1","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1097\/AOG.0000000000003070","article-title":"ACOG Practice Bulletin No. 204: Fetal Growth Restriction","volume":"133","author":"American College of Obstetricians and Gynecologists' Committee on Practice Bulletins\u2014Obstetrics and the Society forMaternal-FetalMedicin","year":"2019","journal-title":"Obstet 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