{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:09:36Z","timestamp":1760242176910,"version":"build-2065373602"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"1174","license":[{"start":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T00:00:00Z","timestamp":1753228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute of Health Research","doi-asserted-by":"crossref","award":["NIHR206522"],"award-info":[{"award-number":["NIHR206522"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The radiotherapy (RT) pathway faces bottlenecks. The Rapid Adaptive and Cost-Effective Radiotherapy (RACE) study evaluates the feasibility of using diagnostic MRI (dMRI) scans for planning prostate MRI-guided adaptive RT (MRIgART).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We audited prostate cancer patients treated with 5-fraction (#) stereotactic body radiotherapy (SBRT) between March 2023 and January 2024, assessing dMRI for RT planning suitability. Planning suitability required a T2-weighted sequence for target\/organs at risk (OAR) delineation and a large field-of-view (LFOV). Scans were classified as RT plan suitable or as having specific issues (incomplete body coverage or slice thickness &amp;gt;10\u00a0mm). Workflow analysis from RT referral to first fraction estimated potential time savings with simulation-free RT (SFRT). Case studies illustrated identified issues and proposed solutions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>dMRIs were available for 93% of patients, with scans originating from various hospitals and conducted on 1.5 Tesla (T) or 3\u2009T MRI scanners. Ideal image characteristics for RT planning were met in 38% of MRIs. Issues such as cropped field of view (FOV) and low slice resolution were identified, but proposed solutions could increase the number of patients with suitable scans to 87%.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The findings suggest that with appropriate technical solutions, most dMRI scans can be adapted for RT planning purposes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge<\/jats:title>\n                  <jats:p>The study highlights the potential of SFRT to reduce treatment delays and improve cost-effectiveness.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjr\/tqaf163","type":"journal-article","created":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T18:28:57Z","timestamp":1753295337000},"page":"1591-1595","source":"Crossref","is-referenced-by-count":0,"title":["Simulation-free radiotherapy on the MR-linac in prostate cancer"],"prefix":"10.1093","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1016-9841","authenticated-orcid":false,"given":"Sian","family":"Cooper","sequence":"first","affiliation":[{"name":"The Institute of Cancer Research , London, SM2 5NG,","place":["United Kingdom"]},{"name":"The Royal Marsden NHS Foundation Trust , London, SM2 5PT,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan","family":"Chick","sequence":"additional","affiliation":[{"name":"The Joint Department of Physics, The Royal Marsden Hospital and the Institute of Cancer Research , London, SM2 5PT,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis","family":"Casey","sequence":"additional","affiliation":[{"name":"The Joint Department of Physics, The Royal Marsden Hospital and the Institute of Cancer Research , London, SM2 5PT,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Alexander","sequence":"additional","affiliation":[{"name":"The Institute of Cancer Research , London, SM2 5NG,","place":["United Kingdom"]},{"name":"The Royal Marsden NHS Foundation Trust , London, SM2 5PT,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simeon","family":"Nill","sequence":"additional","affiliation":[{"name":"The Joint Department of Physics, The Royal Marsden Hospital and the Institute of Cancer Research , London, SM2 5PT,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Oelfke","sequence":"additional","affiliation":[{"name":"The Joint Department of Physics, The Royal Marsden Hospital and the Institute of Cancer Research , London, SM2 5PT,","place":["United 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