{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T07:23:42Z","timestamp":1768634622100,"version":"3.49.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"1176","license":[{"start":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T00:00:00Z","timestamp":1755475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the mid- and long-term outcome of recanalization of accessory hepatic vein (AHV) secondary to hepatic venous outflow obstruction and to compare the mid- and long-term outcome and technical efficacy and safety of AHV recanalization with native hepatic vein (HV) recanalization in hepatic vein outflow tract obstruction (HVOTO) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective observational study, conducted at a single-centre, evaluated the mid- and long-term outcomes of AHV recanalization compared to native HV recanalization in 170 HVOTO patients treated between January 2013 and October 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients were divided into 2 groups based on the type of recanalization performed: AHV (n\u2009=\u200926) and native HV (n\u2009=\u2009144). Technical success was achieved in 100% of AHV cases and 95.8% of native HV cases. The primary patency rates at 1, 3, and 5\u2009years were 95.9%, 92.3%, and 76.9% for AHV and 96.5%, 93%, and 79.1% for native HV, respectively. Significant improvements in liver stiffness, clinical symptoms, and hepatic function were observed post-intervention in both groups, with no significant differences in outcomes. Transplant-free survival rates at 1, 3, and 5\u2009years were also comparable between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrates that AHV recanalization is a safe and effective alternative to native HV recanalization, providing comparable long-term outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Advances in knowledge<\/jats:title>\n                    <jats:p>It offers a promising option for HVOTO patients with dominant AHV and extensive intrahepatic collaterals, further supporting its integration into the stepwise management of HVOTO.<\/jats:p>\n                  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