{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T17:54:32Z","timestamp":1781718872095,"version":"3.54.5"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"1183","license":[{"start":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T00:00:00Z","timestamp":1775865600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Early screening is necessary to prevent increasing osteoporosis and fragility fractures. Though Dual-energy x-ray absorptiometry (DEXA) defines osteoporosis, it does not predict fragility-fractures well. Trabecular structure as seen on MRI may be more sensitive and specific for osteoporosis and distal radius trabecular structure may identify changes earlier. We aimed to compare distal-radius trabecular structure as seen on MRI in patients with normal risk for fragility fractures to those with increased risk of fragility fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ten low-risk and 9 high-risk subjects underwent ultrashort echo time (UTE) MRI sequence scanning of an uninjured distal radius. Structural components included trabecular plate width, plate\u2013rod ratio, plate volume fraction, rod volume fraction, trabecular thickness, pore size, pore size variation, and trabecular density. A t-test or Mann\u2013Whitney U test was conducted to determine differences in trabecular structure between low- and high-risk groups. Specificity and sensitivity were calculated to assess wrist MRI as a screening tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were statistically significant differences between low- and risk-risk groups for all parameters except trabecular thickness (P\u2009&amp;lt;\u2009.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study supports the feasibility of wrist MRI as a screening tool for early osteoporosis. This could potentially enable early prevention. Further study including longitudinal follow-up to determine the ability of this tool to predict fragility fractures is needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Advances in knowledge<\/jats:title>\n                    <jats:p>We compared trabecular structure in wrist MRI of high-risk and low-risk for fragility fracture, finding significant differences with optimal sensitivity\/specificity to predict osteoporosis. Wrist MRI may offer early and effective screening for osteoporosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjr\/tqag080","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T06:43:57Z","timestamp":1776062637000},"page":"1326-1330","source":"Crossref","is-referenced-by-count":0,"title":["Wrist MRI trabecular structure and osteoporosis-a pilot study"],"prefix":"10.1093","volume":"99","author":[{"given":"Allison","family":"Ariniello","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, NYU Grossman School of Medicine , NY 10016,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoliu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Departments of ECE and Radiology, University of Iowa , Iowa City 52242,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Punam K","family":"Saha","sequence":"additional","affiliation":[{"name":"Departments of ECE and Radiology, University of Iowa , Iowa City 52242,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Radiology, NYU Grossman School of Medicine , NY 10016,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven Z","family":"Glickel","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, NYU Grossman School of Medicine , NY 10016,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9092-3930","authenticated-orcid":false,"given":"Ronit","family":"Wollstein","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, NYU Grossman School of Medicine , NY 10016,","place":["United States"]},{"name":"Department of 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