{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T08:00:56Z","timestamp":1784707256660,"version":"3.55.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"1184","license":[{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Peritoneal carcinomatosis remains a major determinant of prognosis and operability in abdominopelvic malignancies, yet conventional CT\/MRI and Fluorine-18([18F])-FDG PET\/CT frequently underestimate peritoneal disease extent, particularly for small, flat, or low-FDG-avid implants. Fibroblast activation protein inhibitor (FAPI) PET targets cancer-associated fibroblasts within the tumour stroma and typically provides high tumour-to-background contrast, particularly in the abdomen. Across head-to-head studies and meta-analyses, FAPI PET\/CT consistently demonstrates higher tumour uptake and tumour-to-background ratios in peritoneal lesions and higher diagnostic sensitivity than FDG PET\/CT, with a downstream increase in imaging-derived peritoneal cancer index that shows the extent of the peritoneal disease. Emerging evidence suggests that improved peritoneal metastases mapping can meaningfully influence clinical decision-making by refining patient selection for cytoreductive surgery and intraperitoneal\/systemic therapies and by reducing the risk of understaging. Current limitations include a predominance of single-centre data in cohorts with a high pre-test probability of peritoneal disease, heterogeneous reference standards, and potential false positives from benign fibro-inflammatory or reparative processes. Ongoing prospective trials, further comparisons with CT\/MRI (including PET\/MRI), implementation studies, and health-economic evaluations will be essential to define optimal indications and confirm outcome-relevant benefit.<\/jats:p>","DOI":"10.1093\/bjr\/tqag087","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T07:49:30Z","timestamp":1776757770000},"page":"1505-1517","source":"Crossref","is-referenced-by-count":1,"title":["FAP-targeted PET imaging in peritoneal carcinomatosis"],"prefix":"10.1093","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6020-1398","authenticated-orcid":false,"given":"Ay\u00e7a","family":"Ar\u00e7ay \u00d6zt\u00fcrk","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, Institut Jules Bordet, H\u00f4pital Universitaire de Bruxelles, Universit\u00e9 Libre de Bruxelles , Brussels, 1070,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Liberale","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery and Digestive Surgical Oncology, Institut Jules Bordet, H\u00f4pital Universitaire de Bruxelles, Universit\u00e9 Libre de Bruxelles , Brussels, 1070,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Flamen","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Institut Jules Bordet, H\u00f4pital Universitaire de Bruxelles, Universit\u00e9 Libre de Bruxelles , Brussels, 1070,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"2026072203064861700_tqag087-B1","doi-asserted-by":"publisher","first-page":"e58","DOI":"10.3802\/jgo.2020.31.e58","article-title":"Incidence and predictors of peritoneal metastases 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