{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T17:08:46Z","timestamp":1789492126536,"version":"build-2803163510"},"reference-count":29,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100000646","name":"JSPS","doi-asserted-by":"publisher","award":["23K14669 and 26K10718"],"award-info":[{"award-number":["23K14669 and 26K10718"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>In radiotherapy for bleeding gastric cancer, no standard definition of response exists; studies have used transfusion-only or transfusion-plus-hemoglobin criteria. After inter-facility transfer or during home care\u2014sometimes following palliative radiotherapy\u2014laboratory results from other facilities are often unavailable, leaving patients inevaluable. We therefore tested whether omitting hemoglobin compromises the precision of response assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In criteria A, referring to our original study, patients were diagnosed as responders when all the following 3 conditions were met: (1) hemoglobin levels \u2265 8.0\u2009g\/dL; (2) 14 consecutive days without blood transfusion before blood sampling; and (3) no salvage treatment. In criteria B, patients were diagnosed as responders when only (2) and (3) of the above conditions were met. The strength of agreement between criteria A and B was estimated by calculating Gwet\u2019s first-order agreement coefficient (AC1) at 4- and 8-week follow-up for patients completing planned radiotherapy with assessable response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In 36 evaluable patients at 4-week follow-up, response rates were 69% (25\/36) by criteria A vs. 78% (28\/36) by criteria B (AC1, 0.86; almost perfect agreement). In 30 evaluable patients at 8-week follow-up, response rates were 83% (25\/30) by criteria A vs. 90% (27\/30) by criteria B (AC1, 0.91; almost perfect agreement).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Criteria A and B showed almost perfect agreement at 4- and 8-week assessments among evaluable patients with available hemoglobin data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Advances in knowledge<\/jats:title>\n                    <jats:p>Among patients with available hemoglobin data, criteria A and B showed almost perfect agreement. The observed agreement may not be fully generalizable to patients without hemoglobin assessment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjr\/tqag196","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:47:36Z","timestamp":1787323656000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparison of response criteria in palliative radiotherapy for bleeding gastric cancer: a secondary analysis of the JROSG 17-3 multicenter prospective observational study"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8066-8753","authenticated-orcid":false,"given":"Yutaro","family":"Koide","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Aichi Cancer Center , Chikusa-ku , Nagoya, 464-8681,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Saito","sequence":"additional","affiliation":[{"name":"Division of Integrative Medical Oncology, 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350-8550,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9014-5577","authenticated-orcid":false,"given":"Terufumi","family":"Kawamoto","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Juntendo University Graduate School of Medicine , Tokyo, 113-8421,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3381-0766","authenticated-orcid":false,"given":"Nobuko","family":"Utsumi","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Saitama Medical Center, Saitama Medical University , Saitama, 350-8550,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhei","family":"Sekii","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Osaka International Medical & Science Center , Osaka, 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312-0057,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunari","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Seirei Mikatahara General Hospital , Shizuoka, 433-8558,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4695-5227","authenticated-orcid":false,"given":"Kei","family":"Ito","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, Department of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital , Tokyo, 113-8677,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norio","family":"Araki","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, National Hospital Organization Kyoto Medical Center , Kyoto, 612-8555,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1354-0108","authenticated-orcid":false,"given":"Miwako","family":"Nozaki","sequence":"additional","affiliation":[{"name":"Department of Radiology, Dokkyo Medical University Saitama Medical Center , Saitama, 343-8555,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joichi","family":"Heianna","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nanbu Tokushukai Hospital , Okinawa, 901-0493,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenta","family":"Murotani","sequence":"additional","affiliation":[{"name":"Biostatistics Center, Kurume University , Fukuoka, 830-0011,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Hirano","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Chiba Tokushukai 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