{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:45:07Z","timestamp":1753875907507,"version":"3.41.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T00:00:00Z","timestamp":1746662400000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Multiple Myeloma represents a plasma cell disorder that can result in hallmark bony destructive change in addition to other signs of myelomatous disease. Imaging often helps in establishing the diagnosis and staging the patient. There are several different imaging modalities that can provide different levels of insight into the disease extent. We report a unique case of multiple myeloma where the progressive nature of the patient\u2019s disease highlights the strengths and limitations of the different imaging approaches. Whole-body MRI represents a noncontrast imaging technique that directly images the bone marrow space, allowing for disease detection that can precede the onset of cortical and trabecular destructive changes. In so doing, whole-body MRI provides a level of insight that far exceeds traditional plain films and even CT. Using the findings from many different imaging modalities (plain films, CT, PET-CT, and whole-body magnetic resonance imaging), we will discuss how imaging can help clinicians to better assess the patient\u2019s disease burden and complement the foundations of traditional disease monitoring (serology, histopathology from biopsy, direct clinical exam, and observation).<\/jats:p>","DOI":"10.1093\/bjrcr\/uaaf028","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T22:58:33Z","timestamp":1746745113000},"source":"Crossref","is-referenced-by-count":0,"title":["Whole-body MRI for a patient with progressive multiple myeloma"],"prefix":"10.1093","volume":"11","author":[{"given":"Jonathan E","family":"Henning","sequence":"first","affiliation":[{"name":"University of South Florida Morsani College of Medicine , Tampa, FL 33602,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiga","family":"Nishihori","sequence":"additional","affiliation":[{"name":"Department of Blood & Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute , Tampa, FL 33612,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ciara","family":"Freeman","sequence":"additional","affiliation":[{"name":"Department of Blood & Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute , Tampa, FL 33612,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Lazarides","sequence":"additional","affiliation":[{"name":"Department of Sarcoma, H. Lee Moffitt Cancer Center and Research Institute , Tampa, FL 33612,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinming","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Hematopathology, H. Lee Moffitt Cancer Center and Research Institute , Tampa, FL 33612,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davis","family":"Kuruvilla","sequence":"additional","affiliation":[{"name":"University of South Florida Morsani College of Medicine , Tampa, FL 33602,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Feuerlein","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Interventional Radiology, H. Lee Moffitt Cancer Center and Research Institute , Tampa, FL 33612,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James R","family":"Costello","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Interventional Radiology, H. Lee Moffitt Cancer Center and Research Institute , Tampa, FL 33612,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,5,8]]},"reference":[{"key":"2025052712482469700_uaaf028-B1","doi-asserted-by":"publisher","first-page":"e418","DOI":"10.1200\/EDBK_159009","article-title":"Updated diagnostic criteria and staging system for multiple myeloma","volume":"35","author":"Rajkumar","year":"2016","journal-title":"Am Soc Clin Oncol Educ Book"},{"volume-title":"Multiple Myeloma. [Updated 2023 Jan 30]. 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