{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T00:01:20Z","timestamp":1792886480352,"version":"4.5.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T00:00:00Z","timestamp":1636070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Gastro-oesophageal reflux disease (GORD) after bariatric surgery is a debated topic. This study investigated the prevalence of GORD and associated oesophageal complications following bariatric procedures\u2014namely, adjustable gastric banding (AGB), sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one-anastomosis gastric bypass (OAGB).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a prospective multicentre study designed to evaluate the long-term effects of bariatric surgery on GORD. Patients were studied at baseline, at &amp;gt;10\u2009years following AGB, SG, and RYGB, and at &amp;gt;3\u2009years following OAGB (due to the more recent recognition of OAGB as a standard bariatric procedure). Patients were assessed by endoscopy and GORD symptom evaluation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 241 patients were enrolled. A minimum follow-up of 10\u2009years was completed by 193 patients following AGB (57 patients), SG (95 patients), and RYGB (41 patients), and of &amp;gt;3\u2009years by 48 subjects following OAGB. GORD symptoms increased following AGB and SG (from 14 to 31.6 per cent and from 26.3 to 58.9 per cent, respectively; P\u2009&amp;lt;\u20090.0001), improved following RYGB (from 36.6 to 14.6 per cent; P\u2009&amp;lt;\u20090.0001), and were unchanged following OAGB. The overall prevalence of erosive oesophagitis was greater in the SG group (74.7 per cent) than in the AGB (42.1 per cent), RYGB (22 per cent), and OAGB (22.9 per cent) groups (P\u2009&amp;lt;\u20090.0001). Barrett\u2019s oesophagus was found only in patients who had SG (16.8 per cent). Biliary-like gastric stagnation was found in a greater proportion of SG and OAGB patients (79.7 and 69.4 per cent, respectively) than in other treatment groups (P\u2009&amp;lt;\u20090.0001). The prevalence of biliary-type reflux into the oesophagus was higher in patients who underwent SG (74.7 per cent), compared with other treatment groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Bariatric surgery leads to gastro-oesophageal complications of variable severity, particularly SG, which can result in a large proportion of patients developing Barrett\u2019s oesophagus.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjs\/znab330","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T11:33:31Z","timestamp":1631100811000},"page":"1498-1505","source":"Crossref","is-referenced-by-count":48,"title":["GORD and Barrett\u2019s oesophagus after bariatric procedures: multicentre prospective study"],"prefix":"10.1093","volume":"108","author":[{"given":"Alfredo","family":"Genco","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences, Sapienza University of Rome , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3800-167X","authenticated-orcid":false,"given":"Lidia","family":"Castagneto-Gissey","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Sapienza University of Rome , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loredana","family":"Gualtieri","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Sapienza University of Rome , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Lucchese","sequence":"additional","affiliation":[{"name":"Department of Surgery, Bariatric and Metabolic Surgery Unit, Santa Maria Nuova Hospital , Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Leuratti","sequence":"additional","affiliation":[{"name":"Department of Surgery, 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