{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:13:56Z","timestamp":1792264436267,"version":"4.4.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is a lack of consensus in selecting patients who do or do not benefit from surgery when patients present with abdominal pain and gallbladder stones are present. This review aimed to give an overview of results from recent trials and available literature to improve treatment decisions in patients with uncomplicated cholecystolithiasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>First, an overview of different symptom criteria for laparoscopic cholecystectomy in patients with uncomplicated cholecystolithiasis is given, based on national and international guidelines. Second, treatment outcomes (absence of biliary colic, pain-free state, biliary and surgical complications) are summarized, with data from three clinical trials. Finally, personal advice for treatment decisions in patients with uncomplicated cholecystolithiasis is provided, based on recent trials, the available literature, and expert opinion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This review describes different guidelines and criteria sets for uncomplicated cholecystolithiasis, provides an overview of outcomes after cholecystectomy, and advises on treatment decisions in patients with abdominal pain and gallbladder stones. After cholecystectomy, biliary colic is resolved in 95 per cent of patients. However, non-specific abdominal pain persists in 40 per cent. Irritable bowel syndrome and functional dyspepsia significantly increase the risk of persistent pain. Age, previous abdominal surgery, baseline pain score on a visual analogue scale, pain characteristics, nausea, and heartburn are part of the SUCCESS criteria, and are associated with clinically relevant pain reduction after gallbladder removal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The surgical community can now give more personalized advice on surgery to improve care for patients with abdominal pain and uncomplicated cholecystolithiasis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjs\/znac154","type":"journal-article","created":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T15:11:03Z","timestamp":1650899463000},"page":"832-838","source":"Crossref","is-referenced-by-count":21,"title":["Tailoring diagnosis and treatment in symptomatic gallstone disease"],"prefix":"10.1093","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4491-5555","authenticated-orcid":false,"given":"Carmen S S","family":"Latenstein","sequence":"first","affiliation":[{"name":"Department of Surgery, RadboudUMC , Nijmegen , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip R","family":"de Reuver","sequence":"additional","affiliation":[{"name":"Department of Surgery, RadboudUMC , Nijmegen , the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"2023063011090713900_znac154-B1","doi-asserted-by":"crossref","first-page":"16024","DOI":"10.1038\/nrdp.2016.24","article-title":"Gallstones","volume":"2","author":"Lammert","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"2023063011090713900_znac154-B2","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/s00464-012-2415-0","article-title":"Epidemiological study of provision of cholecystectomy in England from 2000 to 2009: retrospective analysis of Hospital Episode Statistics","volume":"27","author":"Sinha","year":"2013","journal-title":"Surg Endosc"},{"key":"2023063011090713900_znac154-B3","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.surg.2021.10.025","article-title":"A nationwide analysis of gallbladder surgery in England between 2000 and 2019","volume":"171","author":"Lunevicius","year":"2022","journal-title":"Surgery"},{"key":"2023063011090713900_znac154-B4","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1001\/jama.1993.03510120051029","article-title":"Increased cholecystectomy rate after the introduction of laparoscopic cholecystectomy","volume":"270","author":"Legorreta","year":"1993","journal-title":"JAMA"},{"key":"2023063011090713900_znac154-B5","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1046\/j.1365-2036.2003.01439.x","article-title":"Gallstones\u2014an increasing problem: a study of hospital admissions in England between 1989\/1990 and 1999\/2000","volume":"17","author":"Kang","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"2023063011090713900_znac154-B6","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.jhep.2016.03.005","article-title":"EASL clinical practice guidelines on the prevention, diagnosis and treatment of gallstones","volume":"65","author":"European Association for the Study of the Liver (EASL). 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