{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T14:47:55Z","timestamp":1783781275861,"version":"3.55.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T00:00:00Z","timestamp":1701820800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The necessity of performing a sentinel lymph node biopsy in patients with clinically and radiologically node-negative breast cancer after neoadjuvant chemotherapy has been questioned. The aim of this study was to determine the rate of nodal positivity in these patients and to identify clinicopathological features associated with lymph node metastasis after neoadjuvant chemotherapy (ypN+).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective multicentre study was performed. Patients with cT1\u20133 cN0 breast cancer who underwent sentinel lymph node biopsy after neoadjuvant chemotherapy between 2016 and 2021 were included. Negative nodal status was defined as the absence of palpable lymph nodes, and the absence of suspicious nodes on axillary ultrasonography, or the absence of tumour cells on axillary nodal fine needle aspiration or core biopsy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 371 patients were analysed. Overall, 47 patients (12.7%) had a positive sentinel lymph node biopsy. Nodal positivity was identified in 22 patients (29.0%) with hormone receptor+\/human epidermal growth factor receptor 2\u2212 tumours, 12 patients (13.8%) with hormone receptor+\/human epidermal growth factor receptor 2+ tumours, 3 patients (5.6%) with hormone receptor\u2212\/human epidermal growth factor receptor 2+ tumours, and 10 patients (6.5%) with triple-negative breast cancer. Multivariable logistic regression analysis showed that multicentric disease was associated with a higher likelihood of ypN+ (OR 2.66, 95% c.i. 1.18 to 6.01; P = 0.018), whilst a radiological complete response in the breast was associated with a reduced likelihood of ypN+ (OR 0.10, 95% c.i. 0.02 to 0.42; P = 0.002), regardless of molecular subtype. Only 3% of patients who had a radiological complete response in the breast were ypN+. The majority of patients (85%) with a positive sentinel node proceeded to axillary lymph node dissection and 93% had N1 disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The rate of sentinel lymph node positivity in patients who achieve a radiological complete response in the breast is exceptionally low for all molecular subtypes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjs\/znad401","type":"journal-article","created":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T05:47:26Z","timestamp":1701928046000},"source":"Crossref","is-referenced-by-count":3,"title":["Nodal positivity in patients with clinically and radiologically node-negative breast cancer treated with neoadjuvant chemotherapy: multicentre collaborative study"],"prefix":"10.1093","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0894-4079","authenticated-orcid":false,"given":"Alexandra M","family":"Zaborowski","sequence":"first","affiliation":[{"name":"Department of Breast Surgery, St Vincent\u2019s University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Doogan","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St Vincent\u2019s University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siobhan","family":"Clifford","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Mater Misericordiae University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin","family":"Dowling","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Beaumont Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farah","family":"Kazi","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St James\u2019s Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Delaney","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St James\u2019s Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himanshu","family":"Yadav","sequence":"additional","affiliation":[{"name":"Cork Breast Research Centre, Cork University Hospital , Cork , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Brady","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Bon Secours Hospital Cork , Cork , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Geraghty","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St Vincent\u2019s University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Evoy","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St Vincent\u2019s University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Rothwell","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St Vincent\u2019s University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian","family":"McCartan","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St Vincent\u2019s University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Heeney","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Mater Misericordiae University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchel","family":"Barry","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Mater Misericordiae University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siun M","family":"Walsh","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Mater Misericordiae University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Stokes","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Mater Misericordiae University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm R","family":"Kell","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Mater Misericordiae University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Beaumont Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colm","family":"Power","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Beaumont Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold D K","family":"Hill","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Beaumont Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Connolly","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St James\u2019s Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhafir","family":"Alazawi","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St James\u2019s Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terence","family":"Boyle","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St James\u2019s Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Corrigan","sequence":"additional","affiliation":[{"name":"Cork Breast Research Centre, Cork University Hospital , Cork , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"O\u2019Leary","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Bon Secours Hospital Cork , Cork , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth S","family":"Prichard","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, St Vincent\u2019s University Hospital , Dublin , Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,12,6]]},"reference":[{"key":"2024013108071354100_znad401-B1","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1093\/bjs\/znac131","article-title":"Current practice and surgical outcomes of neoadjuvant chemotherapy for early breast cancer: UK NeST study","volume":"109","author":"Fatayer","year":"2022","journal-title":"Br J Surg"},{"key":"2024013108071354100_znad401-B2","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/bjs\/znad103","article-title":"Neoadjuvant systemic therapy for breast cancer","volume":"110","author":"Zaborowski","year":"2023","journal-title":"Br J Surg"},{"key":"2024013108071354100_znad401-B3","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1016\/S1470-2045(18)30570-9","article-title":"Neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2 blockade for HER2-positive breast cancer (TRAIN-2): a multicentre, open-label, randomised, phase 3 trial","volume":"19","author":"van Ramshorst","year":"2018","journal-title":"Lancet Oncol"},{"key":"2024013108071354100_znad401-B4","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1056\/NEJMoa1910549","article-title":"Pembrolizumab for early triple-negative breast cancer","volume":"382","author":"Schmid","year":"2020","journal-title":"N Engl J Med"},{"key":"2024013108071354100_znad401-B5","doi-asserted-by":"crossref","first-page":"26406","DOI":"10.18632\/oncotarget.25413","article-title":"Triple negative breast cancer subtypes and pathologic complete response rate to neoadjuvant chemotherapy","volume":"9","author":"Santonja","year":"2018","journal-title":"Oncotarget"},{"key":"2024013108071354100_znad401-B6","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S1470-2045(13)70166-9","article-title":"Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study","volume":"14","author":"Kuehn","year":"2013","journal-title":"Lancet Oncol"},{"key":"2024013108071354100_znad401-B7","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1001\/jama.2013.278932","article-title":"Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: the ACOSOG Z1071 (Alliance) clinical trial","volume":"310","author":"Boughey","year":"2013","journal-title":"JAMA"},{"key":"2024013108071354100_znad401-B8","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1200\/JCO.2014.55.7827","article-title":"Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study","volume":"33","author":"Boileau","year":"2015","journal-title":"J Clin Oncol"},{"key":"2024013108071354100_znad401-B9","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1093\/bjs\/znab137","article-title":"Management of the axilla after neoadjuvant chemotherapy in breast cancer patients","volume":"108","author":"Boland","year":"2021","journal-title":"Br J Surg"},{"key":"2024013108071354100_znad401-B10","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1093\/bjs\/znac426","article-title":"Evolution and refinement of magnetically guided sentinel lymph node detection in breast cancer: meta-analysis","volume":"110","author":"Pantiora","year":"2023","journal-title":"Br J Surg"},{"key":"2024013108071354100_znad401-B11","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1093\/bjs\/znac311","article-title":"Ultrasound-assisted carbon nanoparticle suspension mapping versus dual tracer-guided sentinel lymph node biopsy in patients with early breast cancer (ultraCars): phase III randomized clinical trial","volume":"109","author":"Zhang","year":"2022","journal-title":"Br J Surg"},{"key":"2024013108071354100_znad401-B12","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1002\/bjs.12026","article-title":"Toward omitting sentinel lymph node biopsy after neoadjuvant chemotherapy in patients with clinically node-negative breast cancer","volume":"108","author":"van der Noordaa","year":"2021","journal-title":"Br J Surg"},{"key":"2024013108071354100_znad401-B13","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1001\/jamasurg.2017.0562","article-title":"Identification of patients with documented pathologic complete response in the breast after neoadjuvant chemotherapy for omission of axillary surgery","volume":"152","author":"Tadros","year":"2017","journal-title":"JAMA Surg"},{"key":"2024013108071354100_znad401-B14","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1001\/jama.2011.90","article-title":"Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial","volume":"305","author":"Giuliano","year":"2011","journal-title":"JAMA"},{"key":"2024013108071354100_znad401-B15","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1016\/S0140-6736(11)61629-2","article-title":"Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials","volume":"378","author":"Early Breast Cancer Trialists\u2019 Collaborative Group (EBCTCG)","year":"2011","journal-title":"Lancet"},{"key":"2024013108071354100_znad401-B16","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.ejso.2016.12.011","article-title":"Eight-year follow up result of the OTOASOR trial: the Optimal Treatment Of the Axilla \u2013 Surgery or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: a randomized, single centre, phase III, non-inferiority trial","volume":"43","author":"S\u00e1volt","year":"2017","journal-title":"Eur J Surg Oncol"},{"key":"2024013108071354100_znad401-B17","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S1470-2045(14)70460-7","article-title":"Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial","volume":"15","author":"Donker","year":"2014","journal-title":"Lancet Oncol"},{"key":"2024013108071354100_znad401-B18","doi-asserted-by":"crossref","first-page":"4451","DOI":"10.3390\/cancers14184451","article-title":"Factors associated with axillary lymph node status in clinically node-negative breast cancer patients undergoing neoadjuvant chemotherapy","volume":"14","author":"Yu","year":"2022","journal-title":"Cancers (Basel)"},{"key":"2024013108071354100_znad401-B19","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1001\/jamasurg.2018.2696","article-title":"Association of low nodal positivity rate among patients with ERBB2-positive or triple-negative breast cancer and breast pathologic complete response to neoadjuvant chemotherapy","volume":"153","author":"Barron","year":"2018","journal-title":"JAMA Surg"},{"key":"2024013108071354100_znad401-B20","doi-asserted-by":"crossref","first-page":"GS5-05","DOI":"10.1158\/1538-7445.SABCS19-GS5-05","article-title":"Abstract GS5-05: Primary analysis of NRG-BR005, a phase II trial assessing accuracy of tumor bed biopsies in predicting pathologic complete response (pCR) in patients with clinical\/radiological complete response after neoadjuvant chemotherapy (NCT) to explore the feasibility of breast-conserving treatment without surgery","volume":"80","author":"Basik","year":"2020","journal-title":"Cancer Res"},{"key":"2024013108071354100_znad401-B21","doi-asserted-by":"crossref","first-page":"3243","DOI":"10.1245\/s10434-020-09273-0","article-title":"Minimally invasive complete response assessment of the breast after neoadjuvant systemic therapy for early breast cancer (MICRA trial): interim analysis of a multicenter observational cohort study","volume":"28","author":"van Loevezijn","year":"2021","journal-title":"Ann Surg Oncol"},{"key":"2024013108071354100_znad401-B22","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/S1470-2045(22)00613-1","article-title":"Eliminating breast surgery for invasive breast cancer in exceptional responders to neoadjuvant systemic therapy: a multicentre, single-arm, phase 2 trial","volume":"23","author":"Kuerer","year":"2022","journal-title":"Lancet Oncol"},{"key":"2024013108071354100_znad401-B23","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.ejca.2020.11.006","article-title":"Identification of breast cancer patients with pathologic complete response in the breast after neoadjuvant systemic treatment by an intelligent vacuum-assisted biopsy","volume":"143","author":"Pfob","year":"2021","journal-title":"Eur J Cancer"},{"key":"2024013108071354100_znad401-B24","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1200\/JCO.21.02439","article-title":"Intelligent vacuum-assisted biopsy to identify breast cancer patients with pathologic complete response (ypT0 and ypN0) after neoadjuvant systemic treatment for omission of breast and axillary surgery","volume":"40","author":"Pfob","year":"2022","journal-title":"J Clin Oncol"},{"key":"2024013108071354100_znad401-B25","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1093\/bjs\/znac391","article-title":"Diagnostic performance of image-guided vacuum-assisted breast biopsy after neoadjuvant therapy for breast cancer: prospective pilot study","volume":"110","author":"Rossi","year":"2023","journal-title":"Br J Surg"},{"key":"2024013108071354100_znad401-B26","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/cncr.10741","article-title":"Pathobiology of preoperative chemotherapy: findings from the National Surgical Adjuvant Breast and Bowel (NSABP) protocol B-18","volume":"95","author":"Fisher","year":"2002","journal-title":"Cancer"},{"key":"2024013108071354100_znad401-B27","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1245\/s10434-018-6429-2","article-title":"Is low-volume disease in the sentinel node after neoadjuvant chemotherapy an indication for axillary dissection?","volume":"25","author":"Moo","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"2024013108071354100_znad401-B28","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.clon.2019.05.021","article-title":"Axillary surgery following neoadjuvant chemotherapy \u2013 multidisciplinary guidance from the Association of Breast Surgery, Faculty of Clinical Oncology of the Royal College of Radiologists, UK Breast Cancer Group, National Coordinating Committee for Breast Pathology and British Society of Breast Radiology","volume":"31","author":"Gandhi","year":"2019","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"2024013108071354100_znad401-B29","doi-asserted-by":"crossref","first-page":"3340","DOI":"10.1200\/JCO.19.00761","article-title":"Clinicogenomic radiotherapy classifier predicting the need for intensified locoregional treatment after breast-conserving surgery for early-stage breast cancer","volume":"37","author":"Sj\u00f6str\u00f6m","year":"2019","journal-title":"J Clin Oncol"},{"key":"2024013108071354100_znad401-B30","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1200\/JCO.22.00655","article-title":"Development and validation of a genomic profile for the omission of local adjuvant radiation in breast cancer","volume":"41","author":"Sj\u00f6str\u00f6m","year":"2023","journal-title":"J Clin Oncol"},{"key":"2024013108071354100_znad401-B31","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1056\/NEJMoa1415340","article-title":"Regional nodal irradiation in early-stage breast cancer","volume":"373","author":"Whelan","year":"2015","journal-title":"N Engl J Med"},{"key":"2024013108071354100_znad401-B32","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12885-022-09273-1","article-title":"No axillary surgical treatment for lymph node-negative patients after ultra-sonography [NAUTILUS]: protocol of a prospective randomized clinical trial","volume":"22","author":"Jung","year":"2022","journal-title":"BMC Cancer"},{"key":"2024013108071354100_znad401-B33","doi-asserted-by":"crossref","first-page":"101756","DOI":"10.1016\/j.eclinm.2022.101756","article-title":"Patient-reported outcomes for the Intergroup Sentinel Mamma study (INSEMA): a randomised trial with persistent impact of axillary surgery on arm and breast symptoms in patients with early breast cancer","volume":"55","author":"Reimer","year":"2023","journal-title":"EClinicalMedicine"},{"key":"2024013108071354100_znad401-B34","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1186\/s12885-017-3443-x","article-title":"Clinically node negative breast cancer patients undergoing breast conserving therapy, sentinel lymph node procedure versus follow-up: a Dutch randomized controlled multicentre trial (BOOG 2013-08)","volume":"17","author":"van Roozendaal","year":"2017","journal-title":"BMC Cancer"},{"key":"2024013108071354100_znad401-B35","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.breast.2012.06.013","article-title":"Abandoning sentinel lymph node biopsy in early breast cancer? A new trial in progress at the European Institute of Oncology of Milan (SOUND: Sentinel node vs Observation after axillary UltraSouND)","volume":"21","author":"Gentilini","year":"2012","journal-title":"Breast"}],"container-title":["British Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/111\/1\/znad401\/55124478\/znad401.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/111\/1\/znad401\/55124478\/znad401.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T08:07:41Z","timestamp":1706688461000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/doi\/10.1093\/bjs\/znad401\/7459564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,6]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12,6]]},"published-print":{"date-parts":[[2024,1,3]]}},"URL":"https:\/\/doi.org\/10.1093\/bjs\/znad401","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1]]},"published":{"date-parts":[[2023,12,6]]},"article-number":"znad401"}}