{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:58:07Z","timestamp":1785355087895,"version":"3.55.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Medtronic Ib\u00e9rica, S.A"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,2]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Despite their low incidence, leaks result in high morbidity and represent the second cause of death after metabolic bariatric surgery (MBS). The economic impact of diagnosing and managing early leaks after MBS was assessed within the Spanish Health System.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A cost analysis model was developed to estimate the resource consumption of patients with early leaks after laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). Through a comprehensive literature review, an epidemiological framework was established to estimate the incidence of early leaks. Patients were classified into 14 scenarios based on the type of MBS performed, the initial management of the early leak (conservative, endoscopic, or surgical \u00b1 endoscopic), and the need for a secondary treatment. Resource consumption over a 1-year time horizon was determined based on clinical practice, and unit costs in 2025 were obtained from national databases. All parameters were validated by a panel of experts, and sensitivity analyses were conducted to assess the robustness of the results.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Total costs of early leaks reached \u20ac4 199 549, including \u20ac3 469 303 after LSG (82 events\/year) and \u20ac730 246 after LRYGB (18 events\/year). The cost per patient with an early leak after LSG ranged from \u20ac13 358 to \u20ac94 532, with a weighted mean cost of \u20ac42 285, and the cost per patient with an early leak after LRYGB ranged from \u20ac13 110 to \u20ac94 284, with a weighted mean cost of \u20ac40 971. Hospital stays, as well as procedures and interventions, accounted for the largest share of costs. The sensitivity analysis results ranged between \u20ac1 189 220 and \u20ac7 209 878.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Early leaks after MBS markedly increase health resource utilization, mainly due to an increase in hospital stays, with costs increasing in line with case complexity.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/bjs\/znag072","type":"journal-article","created":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T14:57:22Z","timestamp":1783781842000},"source":"Crossref","is-referenced-by-count":0,"title":["Short-term economic impact of early leaks after metabolic bariatric surgery"],"prefix":"10.1093","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0764-7179","authenticated-orcid":false,"given":"Jos\u00e9 M","family":"Balibrea","sequence":"first","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Fisiopatolog\u00eda de la Obesidad y Nutrici\u00f3n, Instituto de Salud Carlos III , Madrid ,","place":["Spain"]},{"name":"Department of General Surgery, Hospital Germans Trias i Pujol , Badalona ,","place":["Spain"]},{"name":"Department of Surgery, Universitat Aut\u00f2noma de Barcelona , Bellaterra ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0889-4585","authenticated-orcid":false,"given":"Javier","family":"Osorio","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Hospital Cl\u00ednic de Barcelona , Barcelona ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaqu\u00edn","family":"Resa","sequence":"additional","affiliation":[{"name":"Department of Laparoscopic Surgery, HLA Cl\u00ednica Montpellier , Zaragoza ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"\u00c1lvarez-Orozco","sequence":"additional","affiliation":[{"name":"Health Economics & Outcomes Research, Medtronic 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