{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T19:18:08Z","timestamp":1788376688247,"version":"build-2803163510"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Effective multimodal analgesia is essential after minimally invasive colorectal surgery. This randomized trial evaluated whether adding surgeon-performed surgical rectus sheath block (SRSB) or laparoscopic bilateral dual transversus abdominis plane (BD-TAP) block to intravenous patient-controlled analgesia (IV-PCA) improved postoperative quality of recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single-centre, three-arm superiority trial randomized adults undergoing minimally invasive colorectal resection (1 : 1 : 1) by stratified block allocation at a Japanese cancer centre. Patients and outcome assessors were blinded. The primary outcome was the Japanese version of the 15-item Quality of Recovery questionnaire (QoR-15) score 24\u2005h after arrival in the postanaesthesia care unit. Missing postoperative QoR-15 item responses were handled using multiple imputation, and treatment effects were estimated using ANCOVA adjusted for the four randomization stratification factors. Each primary comparison used a Bonferroni-adjusted one-sided significance level of 0.025. Secondary outcomes included the 48-h QoR-15 score, postoperative pain scores, time to first rescue analgesia, and cumulative consumption of analgesics and antiemetics over 48\u2005h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Between July 2024 and December 2025, 320 patients were randomized (control, 110; SRSB, 107; and BD-TAP block, 103); 309 were analysed (105, 103, and 101 respectively). Compared with control, BD-TAP block resulted in a higher 24-h QoR-15 score (adjusted mean difference 10.44 (95% c.i. 3.06 to 17.83) points; one-sided P = 0.003), whereas superiority of SRSB was not demonstrated (adjusted mean difference 5.50 (95% c.i. \u22121.88 to 12.89) points; one-sided P = 0.072). At 48\u2005h, the adjusted mean difference for BD-TAP block versus control was 8.01 (95% c.i. 0.18 to 15.83) points (two-sided P = 0.045), an exploratory finding unadjusted for multiplicity. The median time to first rescue analgesia was longer with SRSB (27.8\u2005h) and BD-TAP block (25.3\u2005h) than control (3.3\u2005h), but cumulative 48-h fentanyl consumption and length of hospital stay did not differ significantly. No block-related complications were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>BD-TAP block resulted in better 24-h recovery than IV-PCA alone. Superiority of SRSB was not demonstrated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration number<\/jats:title>\n                    <jats:p>jRCT1031240153 (Japan Registry of Clinical Trials).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjs\/znag109","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T11:36:56Z","timestamp":1786448216000},"source":"Crossref","is-referenced-by-count":0,"title":["Surgical rectus sheath block\n                    <i>versus<\/i>\n                    laparoscopic bilateral dual transversus abdominis plane block after minimally invasive colorectal cancer surgery: randomized clinical trial of impact on recovery"],"prefix":"10.1093","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0705-816X","authenticated-orcid":false,"given":"Takeharu","family":"Kato","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5143-6312","authenticated-orcid":false,"given":"Shunsuke","family":"Tsukamoto","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri","family":"Oishi","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gen","family":"Tomizawa","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yudai","family":"Kumamoto","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Takura","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Nagata","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9751-3309","authenticated-orcid":false,"given":"Yasuyuki","family":"Takamizawa","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsufumi","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3366-3826","authenticated-orcid":false,"given":"Yukihide","family":"Kanemitsu","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, National Cancer Centre Hospital , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"key":"2026090214564546400_znag109-B1","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2025.1524308","article-title":"Global, regional, and national disease burden and prediction analysis of colorectal cancer attributable to tobacco, alcohol, and obesity from 1990 to 2030","volume":"15","author":"Deng","year":"2025","journal-title":"Front Oncol"},{"key":"2026090214564546400_znag109-B2","author":"Foundation for Promotion of Cancer Research"},{"key":"2026090214564546400_znag109-B3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s00268-018-4844-y","article-title":"Guidelines for perioperative care in elective colorectal surgery: Enhanced Recovery After Surgery (ERAS\u00ae) Society recommendations: 2018","volume":"43","author":"Gustafsson","year":"2019","journal-title":"World J Surg"},{"key":"2026090214564546400_znag109-B4","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.bpa.2017.07.002","article-title":"Opioid-related side effects: postoperative ileus, urinary retention, nausea and vomiting, and shivering. 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