{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:55:44Z","timestamp":1761630944401,"version":"3.41.2"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,1,9]],"date-time":"2021-01-09T00:00:00Z","timestamp":1610150400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>This study aimed to identify a subgroup of recipients at low risk of haemorrhage, bile leakage and ascites following liver transplantation (LT).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Factors associated with significant postoperative ascites (more than 10\u00a0ml\/kg on postoperative day 5), bile leakage and haemorrhage after LT were identified using three separate multivariable analyses in patients who had LT in 2010\u20132019. A model predicting the absence of all three outcomes was created and validated internally using bootstrap procedure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Overall, 944 recipients underwent LT. Rates of ascites, bile leakage and haemorrhage were 34.9, 7.7 and 6.0 per cent respectively. The 90-day mortality rate was 7.0 per cent. Partial liver graft (relative risk (RR) 1.31; P\u2009=\u20090.021), intraoperative ascites (more than 10\u00a0ml\/kg suctioned after laparotomy) (RR 2.05; P\u2009=\u20090.001), malnutrition (RR 1.27; P\u2009=\u20090.006), portal vein thrombosis (RR 1.56; P\u2009=\u20090.024) and intraoperative blood loss greater than 1000\u00a0ml (RR 1.39; P\u2009=\u20090.003) were independently associated with postoperative ascites and\/or bile leak and\/or haemorrhage, and were introduced in the model. The model was well calibrated and predicted the absence of all three outcomes with an area under the curve of 0.76 (P\u2009=\u20090.001). Of the 944 patients, 218 (23.1 per cent) fulfilled the five criteria of the model, and 9.6 per cent experienced postoperative ascites (RR 0.22; P\u2009=\u20090.001), 1.8 per cent haemorrhage (RR 0.21; P\u2009=\u20090.033), 4.1 per cent bile leak (RR 0.54; P\u2009=\u20090.048), 40.4 per cent severe complications (RR 0.70; P\u2009=\u20090.001) and 1.4 per cent 90-day mortality (RR 0.13; P\u2009=\u20090.004).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>A practical model has been provided to identify patients at low risk of ascites, bile leakage and haemorrhage after LT; these patients could potentially qualify for inclusion in non-abdominal drainage protocols.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjsopen\/zraa031","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T14:10:17Z","timestamp":1615990217000},"source":"Crossref","is-referenced-by-count":2,"title":["Practical model to identify liver transplant recipients at low risk of postoperative haemorrhage, bile leakage and ascites"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9592-2520","authenticated-orcid":false,"given":"C","family":"Hobeika","sequence":"first","affiliation":[{"name":"Department of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, Beaujon Hospital, Assistance Publique\u2013H\u00f4pitaux de Paris and Universit\u00e9 de Paris , Clichy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4997-3730","authenticated-orcid":false,"given":"F","family":"Cauchy","sequence":"additional","affiliation":[{"name":"Department of Hepato-Pancreato-Biliary Surgery and 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