{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:03:29Z","timestamp":1792785809156,"version":"4.5.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"vor","delay-in-days":61,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"AM-ETHOS Duke-NUS Medical Student Fellowship","award":["AM-ETHOS01\/FY2019\/14-A14"],"award-info":[{"award-number":["AM-ETHOS01\/FY2019\/14-A14"]}]},{"name":"SingHealth Duke-NUS Global Health Institute Student Research Award","award":["SDGHI\/FY2019\/SRA\/02\/10-19"],"award-info":[{"award-number":["SDGHI\/FY2019\/SRA\/02\/10-19"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Haemorrhoids is a common chronic disease that can significantly impact patients\u2019 quality of life. Yet, few studies have evaluated health-related quality of life (HRQoL) of patients with haemorrhoids before and after treatment. This study investigated the HRQoL of patients with haemorrhoids before and after treatment and the change in HRQoL from baseline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective observational study of patients with haemorrhoids was conducted at two public hospitals in Kandy, Sri Lanka. Two questionnaires assessing symptom severity and haemorrhoid-specific QoL were administered at initial consultation and at 4- and 8-week follow-ups after treatment (sclerotherapy, rubber band ligation (RBL), haemorrhoidectomy or evacuation of haematoma). The primary outcome was the least squares (LS) change of HRQoL score from baseline, measured using the Short Health Scale adapted for Haemorrhoidal Disease (4 domains: symptom load, interference with daily activities, concern, general well-being).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In 48 patients selected for this study, LS mean change from baseline showed significant improvement in HRQoL across all domains and total Short Health Scale adapted for Haemorrhoidal Disease score at 4- and 8-week follow-ups (P\u2009&amp;lt;\u20090.001). Difference in LS mean change from baseline also showed continued improvement of HRQoL from week 4 to week 8 (P\u2009&amp;lt;\u20090.010). \u2018Concern\u2019 showed greatest improvement at 4 and 8\u2009weeks (P\u2009&amp;lt;\u20090.001). Averaged LS mean changes from baseline showed RBL had greater improvement of HRQoL compared with sclerotherapy (P\u2009=\u20090.004).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with haemorrhoids had improved HRQoL after invasive treatment. Haemorrhoid-specific QoL is an important component of the extent of disease and can serve as an aid to guide treatment, assess outcomes and monitor disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjsopen\/zrab014","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T15:27:02Z","timestamp":1612538822000},"source":"Crossref","is-referenced-by-count":8,"title":["Improvement in quality of life among Sri Lankan patients with haemorrhoids after invasive treatment: a longitudinal observational study"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9738-0614","authenticated-orcid":false,"given":"S Y J","family":"Keong","sequence":"first","affiliation":[{"name":"Duke-NUS Medical School , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H K","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M D","family":"Lamawansa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Teaching Hospital Peradeniya , Kandy, Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"Allen","sequence":"additional","affiliation":[{"name":"Duke-NUS Medical School , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z L","family":"Low","sequence":"additional","affiliation":[{"name":"Duke-NUS Medical School , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"\u00d8stbye","sequence":"additional","affiliation":[{"name":"Duke-NUS Medical School , 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