{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:16:15Z","timestamp":1788480975001,"version":"build-2803163510"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T00:00:00Z","timestamp":1657238400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Extracervical approaches for thyroidectomy are seldom explored in the western population. The objective of this study was to evaluate the outcomes of hemithyroidectomy via endoscopic unilateral axillo-breast approach (UABA) with gas insufflation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Method<\/jats:title>\n                  <jats:p>Consecutive patients undergoing UABA hemithyroidectomy for symptomatic benign or cytologically indeterminate nodules (Bethesda III lesions) of less than 5\u2005cm from July 2015 to December 2020 at three European institutions were included. Patients were excluded if presenting with a BMI more than 25\u2005kg\/m2, had previous neck surgery and\/or radiation, had bilateral thyroid lesions, retrosternal goitre, Hashimoto thyroiditis or Graves\u2019 disease. Follow-up was carried out at 2 weeks, 3 months and 1 year. Outcomes of interest were surgical (including operating time, mean duration of hospital stay and complications) and self-assessed cosmetic outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Out of 984 patients treated with hemithyroidectomy during the study interval, 253 were selected, including 214 women and 39 men. Patients\u2019 mean age was of 46.6 years with a mean BMI of 22.57. Mean operating time was 72.9 minutes. A transient recurrent laryngeal nerve injury was reported in 3.6 per cent of the patients, but none was persistent. Transient pectoral\/cervical hypoesthesia was noted in 24.1 per cent of patients, with no permanent hypoesthesia. Skin burns and subcutaneous hematoma developed in 2.4 per cent and 2 per cent of patients but resolved within the third month after surgery. There was no tracheal\/oesophageal perforation, conversion to open surgery or reoperation. The final pathology revealed 241 benign nodules, nine underlying papillary thyroid carcinomas, and three cases of follicular carcinoma. Hospital discharge was achieved on the first in 68.8 per cent of the patients and on the second postoperative day in 31.2 per cent of the cases. All patients were satisfied with the cosmetic aspect.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In selected patients, UABA with gas insufflation for hemithyroidectomy could be performed for the treatment of unilateral thyroid pathologies.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjsopen\/zrac087","type":"journal-article","created":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T03:46:37Z","timestamp":1657251997000},"source":"Crossref","is-referenced-by-count":10,"title":["Thyroidectomy via unilateral axillo-breast approach (UABA) with gas insufflation: prospective multicentre European study"],"prefix":"10.1093","volume":"6","author":[{"given":"David","family":"Saavedra-Perez","sequence":"first","affiliation":[{"name":"Unit of Medical and Surgical Endocrinology, Endocrine Surgery, Department of General and Digestive Surgery, Hospital Clinic of Barcelona, University of Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marti","family":"Manyalich","sequence":"additional","affiliation":[{"name":"Unit of Medical and Surgical Endocrinology, Endocrine Surgery, Department of General and Digestive Surgery, Hospital Clinic of Barcelona, University of Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Dominguez","sequence":"additional","affiliation":[{"name":"Unit of Medical and Surgical Endocrinology, Endocrine Surgery, Department of General and Digestive Surgery, Hospital Clinic of Barcelona, University of Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Vila\u00e7a","sequence":"additional","affiliation":[{"name":"Endocrine Surgery, Department of General and Digestive Surgery, Hospital da Luz Arr\u00e1bida, Universidade do Minho , Porto , Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Jordan","sequence":"additional","affiliation":[{"name":"Endocrine Surgery, Department of General and Digestive Surgery, University Hospital Nuestra Se\u00f1ora de la Candelaria, La Laguna University , Tenerife , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A","family":"Lopez-Boado","sequence":"additional","affiliation":[{"name":"Unit of Medical and Surgical Endocrinology, Endocrine Surgery, Department of General and Digestive Surgery, Hospital Clinic of Barcelona, University of Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon","family":"Rull","sequence":"additional","affiliation":[{"name":"Unit of Medical and Surgical Endocrinology, Endocrine Surgery, Department of General and Digestive Surgery, Hospital Clinic of Barcelona, University of Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar","family":"Vidal","sequence":"additional","affiliation":[{"name":"Unit of Medical and Surgical Endocrinology, Endocrine Surgery, Department of General and Digestive Surgery, Hospital Clinic of Barcelona, University of Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,7,8]]},"reference":[{"key":"2023020302102242200_zrac087-B1","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1001\/jama.2018.0898","article-title":"The diagnosis and management of thyroid nodules: a review","volume":"319","author":"Durante","year":"2018","journal-title":"JAMA"},{"key":"2023020302102242200_zrac087-B2","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1089\/thy.2015.0407","article-title":"American thyroid association statement on remote-access thyroid 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